Associate Scientist - Protein Therapeutics

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Job Description

Associate Scientist - Protein Therapeutics

Gilead Sciences currently has an exciting opportunity for a highly motivated associate scientist to join our protein purification, QC, and logistics group within the Protein Therapeutics Department. The successful candidate is expected to work independently and display professional judgment in all aspects of daily research and presentations. This person will work in collaboration with research project teams to generate and validate potential therapeutic proteins, surrogate tool molecules, and bioconjugates.

Responsibilities:

Perform protein purification, conjugation, QC, and sample bank registration to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas

Prepare technical reports, quantitative analyses, and summaries for entry into Excel, PPT, and ELN formats

Use good oral and written communication skills to relay scientific data

Actively participate in group meetings, present the results of one’s work, interpret data, and draw conclusions regarding presented material and maintain awareness of cutting-edge technical developments and scientific knowledge and apply these where possible to improve process efficiency

Education:

BS in Biology, Biochemistry, Chemistry or related field with at least 4 years of relevant experience OR MS with at least 2 years of relevant experience with below listed characteristics and techniques for the position.

Required skills:

Strong background in protein sciences and protein biochemistry

Direct industry experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and next generation biologics (e.g., bispecific antibodies, immunocytokines)

Hands-on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using Akta Avant/Pure or BioRad NGC

Hands-on experience in protein conjugation technologies (e.g. NHS chemistry, malemide chemistry, enzymatic conjugation) and the related QC

Proficiency with various analytical protein characterization techniques such as SEC-HPLC or UHPLC, SDS-PAGE, Endosafe

Ability to perform method development and write protocols

Proficiency in editing and writing AKTA methods using Unicorn software

Detailed record-keeping is a must

Ability to multi-task and work in a fast-paced team environment

Must be team-oriented, professional, hard-working, and interested in learning new skills

Ability to analyze and present experimental data with proper software and other necessary tools

Preferred Education and Experience:

Experience in conjugation and characterization of ADC (antibody drug conjugate) would be a plus

BS in Biology, Biochemistry, Chemistry with at least 6 years of relevant experience preferred

MS in Biology, Biochemistry, Chemistry with at least 3 years of relevant experience preferred

The salary range for this position is: $109,650.00 - $141,900.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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