Scientist, Downstream Process Development

Advancing medicine to save lives. Together.

Thanks to many decades of experience and our passion for what we do, we make an essential contribution to the global availability of biopharmaceuticals, especially for patients with rare and serious diseases.

Rentschler Biopharma SE is a leading contract development and manufacturing organization (CDMO) focused exclusively on client projects. We offer customized full-service solutions for bioprocess development and the production of complex biopharmaceuticals. As a German family-owned company with an international footprint and global reach, we combine experts, expertise and years of experience to develop best-in-class solutions – together with our clients.

Rentschler Biopharma has approximately 1,400 employees and is headquartered in Laupheim, Germany, with a site in Milford, MA, USA. In 2024, we joined the United Nations Global Compact, underlining our commitment to sustainability.

As an independent family-owned company, we live by the motto: Many hands, many minds - ONE TEAM! Open, respectful cooperation characterizes our working environment, where quality awareness, diligence and responsibility are our top priorities. With all the diversity of our talents in the Rentschler team, we pursue one vision together: advancing medicine to save lives.

Duties and Responsibilities

Assist in the development of scale-able and robust downstream processes including process characterization, and/or technology transfer leading to clinical and commercial GMP manufacturing for multiple client projects meeting the project deliverables

Help design experiments related to development, optimization, scale-up of all steps in a monoclonal antibody and bispecific antibody purification process and viral clearance study, execute studies together with junior members

Identify, evaluate, and implement new and existing technologies to improve process efficiency, control, and understanding

Ability to work in a team environment

Apply DOE and other advanced statistical techniques to design experiments related to process characterization

Author high-quality documents, including technical reports, SOPs, and experimental protocols

Qualifications

Bachelor’s degree in STEM with:

3+ years of hands-on experience

Masters degree with 1+ year of hands-on experience

Solid theoretical knowledge and hands-on experience in protein purification and analytical characterization

Hands-on experience in protein purification and analytical characterization

Hands-on experience with purification unit operations including filtration, different mode chromatography, UF/DF, AKTA, UNICORN, centrifugation

Advanced ability with Microsoft Office (Word, Excel, and PowerPoint)

Ability to support MFG floor activities when needed

Ability to adapt to change priorities of the business

Working Conditions

Laboratory environment working with chemical reagents and analytical equipment

Personal Protective Equipment must be worn as required

Normal office working conditions: computer, phone, files, fax, copier

Will interact with other people

Pace may be fast and job completion demands may be high

Physical Requirements

Frequent lifting up to 10 lbs

Frequent standing/walking to work in lab environment for extended periods

Frequent sitting for extended periods to use computer

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