R&D Scientist Assay Development-Protein Chemistry

Sarmal, an innovative biotech company based in San Diego, California, is seeking a highly skilled R&D Scientist specializing in Enzyme Engineering to join our cutting-edge research team. We are developing revolutionary genomics platforms that aim to transform the fields of genetic testing and sequencing.

Key Responsibilities:

Design and optimize enzymes for our proprietary TEEM and FLASH platforms

Develop and conduct enzyme-substrate interaction studies

Lead research projects focused on improving enzyme performance and stability

Perform protein modifications to enhance enzymatic activity and specificity

Develop and execute rate improvement assays under various conditions

Collaborate with cross-functional teams to advance project goals

Contribute to the development of intellectual property and patent applications

Required Qualifications:

Ph.D. in Biochemistry, Molecular Biology, or a closely related field with a focus on enzyme engineering, purification and assay development/optimization

5+ years of post-doctoral experience in enzyme research and development

Extensive hands-on experience with protein isolation and purification techniques

Strong understanding of enzymatic assays and reaction buffer optimizations

Proven expertise in protein modifications and enzyme kinetics

Demonstrated ability to design and execute complex enzyme engineering experiments

Excellent problem-solving skills and attention to detail

Strong written and verbal communication skills

Preferred Qualifications:

Industry experience in biotechnology or pharmaceutical sectors

Extensive experience working with nucleic acid polymerases and modifying enzymes

Strong background in modified nucleotides and their impact on enzyme activity

Familiarity with next-generation sequencing technologies and their enzymatic foundations

Experience with enzyme reaction optimization

Track record of publications in peer-reviewed journals and/or patents in enzyme engineering

Experience in project management and team leadership

We Offer:

Competitive salary commensurate with experience

Opportunity to work on groundbreaking enzyme engineering projects

State-of-the-art laboratory facilities in La Jolla, CA

Collaborative and innovative work environment

Professional development and growth opportunities

Join our team of 10 members, along with advisors and consultants, and contribute to the development of disruptive technologies that aim to revolutionize genetic testing and sequencing.

Sarmal is an equal opportunity employer and values diversity in our workforce.