Research Scientist, Biology

This scientist will play a critical role in the design, execution, and analysis of in vitro and ex vivo assays aimed at characterizing ion channel modulators. The role requires deep hands-on experience with cell-based assay technologies, supporting ion channel-focused drug discovery programs.

Key Responsibilities:

Perform routine mammalian tissue culture (cell lines and neuronal cultures), including neuronal differentiation and maintenance of iPSC-derived neuronal models.

Harvest rodent tissues, dissect specific brain regions, and prepare samples for downstream applications.

Design and execute manual patch-clamp, automated patch-clamp (APC), and/or multi-electrode array (MEA) experiments to evaluate ion channel modulators in recombinant cell lines, primary neurons, and iPSC-derived neurons.

Analyze, interpret, and present experimental data in internal team meetings and contribute to technical reports and data packages.

Maintain meticulous lab records, adhere to SOPs and lab safety regulation guidelines, and ensure high data integrity and reproducibility.

Required Qualifications:

BS/MS in Neuroscience, Pharmacology, Physiology, Cell Biology, or a related field.

Minimum 3 years of hands-on experience in vitro pharmacology in academic, biotech, or pharmaceutical settings.

Strong background in mammalian cell culture including primary and iPSC-derived neurons.

Experience with tissue harvesting, brain region dissection, and processing of neural tissue.

Experience in manual patch-clamp electrophysiology, automated patch-clamp electrophysiology (APC), multielectrode array (MEA), or ELISA techniques is strongly preferred.

Key Attributes:

Detail-oriented in experimental execution, with strong problem-solving skills and scientific curiosity.

Effective communicator, both written and verbal.

Team-oriented with the ability to work in a fast-paced, interdisciplinary environment.

High personal integrity and self-motivation with a strong sense of accountability.

This is an excellent opportunity to contribute to impactful ion channel drug discovery efforts in a dynamic and collaborative research environment.