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Scientist - Center for Patient Derived Models

Company:
Dana-Farber Cancer Institute
Location:
Boston, MA, 02215
Posted:
May 15, 2025
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Description:

Job Ref:44696

Location:450 Brookline Ave, Boston, MA 02215

Category:Research Laboratory

Employment Type:Full time

Work Location:Onsite: 100% onsite

Overview

The Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute (DFCI) is at the forefront of advancing modeling science and research. Our focus is on utilizing patient-derived cell lines (PDCL), organoids (PDO), xenografts (PDX), and patient cells in functional precision medicine (FPM) studies. Located in Boston, DFCI is a leader in cancer research and patient care, committed to conquering cancer, HIV/AIDS, and related diseases. We are dedicated to fostering an inclusive, diverse, and equitable environment, providing compassionate care, and promoting public health, especially among high-risk and underserved populations.

Position Overview:

We are seeking a Research Scientist to join our dynamic team. The successful candidate will contribute to our understanding of precision medicine, cancer biology, treatment, and diagnostics across all cancer types in adults and children. This role involves applying cutting-edge techniques to develop patient-derived cancer models and collaborating with academic and biopharma industry partners.

Please visit our site with this link.

Center for Patient Derived Models (CPDM) - Dana-Farber Cancer Institute Boston, MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Responsibilities

Key Responsibilities:

- Design and execute experiments aligned with the center’s mission to advance functional precision medicine.

- Develop and conduct in-vitro drug screens using advanced methods and complex patient-derived models.

- Perform preclinical in-vivo assays in mouse models as needed.

- Handle and process patient tissue samples.

- Analyze experimental data, interpret results, and prepare reports, grant applications, and presentations.

- Stay updated with relevant literature and research publications.

- Supervise and mentor junior staff.

- Develop, modify, and improve standard operating procedures.

- Utilize computer-interfaced equipment and automation for research tasks.

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