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Senior Systems Integration Engineer

Company:
Pleno Inc.
Location:
San Diego, CA
Posted:
May 14, 2025
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Description:

As a Senior Systems Integration Engineer at Pleno you will have a key role in optimizing and ensuring the robustness and reliability of our groundbreaking RAPTOR™️ platform. You will participate in component and system-level design activities, define, and execute test plans, interpret results and make recommendations to technical teams. You will collaborate with our Consumables, Applications, Software, and Hardware teams to deliver a best-in-class product to our commercial partners.

In this role you will:

Generate deep component and system-level knowledge of our instrument platform through extensive evaluation and testing

Drive execution, integration and testing activities of our pre-commercialization instruments, participating actively in experimental activities in a hands-on capacity

Validate and verify new instrument software and feature releases, ensuring stable releases to the application teams

Develop and automate instrument recipes and processes for instrument bring up and maintenance including calibration routines for instrument-specific parameters

Design and execute tests to evaluate instrument and system performance, explore critical parameters and assess their sensitivity, identify failure modes, and interpret results to iteratively improve performance and robustness

Create and maintain records for all testing activities such as generating parameter databases and performance and failure trackers through Jira work management tools and proper documentation

With input from other technical teams, coordinate and prioritize testing activities, inform on processes and practices to improve performance and reduce issues

Perform data analysis of complex image-based assays

Make results-based recommendations for project directions and tool selection

Synthesize and present results to team members and leadership

To be successful in this role you have:

A demonstrated track record of troubleshooting complex systems through in-depth technical investigations

Scientific and/or engineering background with years of experience in the development and integration of complex diagnostic tools

Strong software skills with experience in scripting and programming in Python

Experience in creating visual and other quantitative tools to track system performance and failure modes

Strong experimental design skills including DOEs

Knowledge of issue tracking tools such as Jira and experience in the creation and maintenance of instrument run databases

Great attention to detail, spirit of collaboration and positive attitude when dealing with intricate problems in pressing timelines

Experience in the biotechnology, life sciences lab equipment, or medical device space

Experience in design verification and validation activities (It is highly desirable to have experience in a full cycle of product development in the biomedical device industry)

Education & Experience

B.Sc., Master’s, PhD or equivalent degrees in Engineering, Biochemistry, Chemistry, Physics, Bioinformatics, or other related technical fields.

A minimum industry experience of 5 years (B.Sc.) or equivalent experience through advanced education (M.Sc./M.Eng. Ph.D.)

Note: This position is based onsite in San Diego and will require regular participation at our office/lab in San Diego, CA - to apply you should be resident in the greater San Diego County area.

The compensation range for this position spans is $130,000 to $150,000. (Compensation decisions are dependent on several factors including, but not limited to, level of the position, skills, knowledge and experience, internal equity, and alignment with comparable market data.)

About Pleno

Pleno is a multidisciplinary team of scientists and technologists focused on collaboration and asking questions. We strive to find the best, and most meaningful answers for biochemistry and engineering problems in our mission to build a revolutionary multi-omic instrument platform that will revolutionize biological target detection for a wide array of meaningful applications. Come join us to be a part of the biomedical revolution!

We value our Pleno people and each person's wellbeing is important to us, so in addition to offering industry competitive compensation, we also offer the following:

Equity - everyone at Pleno has a stake in our success

Generous company-sponsored contribution to health, dental and vision coverage

Company contributions to life insurance, short term and long term disability

Flexible Paid Time Off - plus 11 paid holidays including a winter break company-wide close

Parental Leave - we value our families and include generous parental leave and wage replacement

Free catered onsite meals twice weekly

Fitness and wellness facilities

Regular opportunities to spend social time together like happy hours & team building events

We are hiring for positions onsite at our office/lab in San Diego, CA – all positions are full time employment. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, or on the basis of disability, gender identity, and sexual orientation. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form.

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