Biochemist Biophysicist

Biochemist Biophysicist needs 2+ years hands-on experience in biophysics, bioconjugation, protein labeling, or a combination thereof.

Biochemist Biophysicist requires:

• BS, MS, or PhD in Biochemistry, Chemical Biology, or related field. •

• 2+ years hands-on experience in biophysics, bioconjugation, protein labeling, or a combination thereof.

• Direct knowledge in assay development and utilizing SPR/BLI (e.g. Biacore or Octet) or LCMS technologies (e.g. QTOF or Orbitrap)

• Experience in method or assay development utilizing a variety of LCMS technology (e.g. QTOF or Orbitrap).

• Working knowledge of fluorescent based method or assay development (e.g. FP, FRET, etc).

• Working knowledge in assay development and utilizing SPR/BLI (e.g. Biacore or Octet).

• Excellent interpersonal skills with the ability to communicate and interact well with colleagues at all levels.

• Committed to staying current with the latest scientific breakthroughs in structure-based drug design and biophysical analysis.

Biochemist Biophysicist duties:

• Work closely with senior scientists to accomplish team objectives and research milestones.

• • Contribute to the development and optimization of conjugation schemes to achieve the required product specifications.

• Commit to producing and maintaining the highest standard of quality in antibody-conjugate productions.

• Perform the following bioconjugation procedures; 1) Antibody and recombinant protein isolation and purification, 2) Purification of antibodies and conjugates using various liquid chromatography methods (IEX, SEC, HIC); 3) Antibody and conjugate validation via various functional tests, 4) Biophysical characterization of proteins and conjugates (e.g., UV/VIS spectrophotometry, DLS, SEC-MALS, native mass-spectrometry Tm or Tagg determination).

• Characterize protein-ligand and protein-protein interactions by a variety of methods including but not limited to; Intact protein and peptide-based mass spectrometry, native mass spectrometry, fluorescence spectroscopy, SPR, BLI, and DSF. •