Postdoctoral Fellow, Diabetes

The New York Stem Cell Foundation (NYSCF) Research Institute is a rapidly growing and highly successful nonprofit whose mission is to accelerate cures through stem cell research.

NYSCF is seeking to immediately fill a Postdoctoral Fellow to join the Diabetes team.

The project will focus on differentiation of induced pluripotent stem cells (iPSC) into pancreatic beta cell organoids for disease modeling and drug discovery with a major focus on Type 2 diabetes.

In addition to the Diabetes team, you will work closely with a broader interdisciplinary team, including members of the Global Stem Cell ArrayTM, project management, biologists, automation engineers, software specialists, and operations.

In this role, you will have the unique opportunity to collaborate directly with the Center for Precision Health Research, NHGRI.

You will contribute to the experimental work and write publications resulting from this collaboration.

You are a highly self-motivated applicant with a strong interest in stem cell research.

You will have a solid background in human pluripotent stem cell culture, including directed differentiation, and specific experience with differentiation towards the pancreatic lineage.

In addition to these interests, the potential to leverage high-throughput liquid handling is at the heart of this role, alongside the opportunity to enable high-throughput large-scale genotype-phenotype association studies that utilize the iPSC disease model.

What you’ll do:

Perform population-based diabetes disease modeling

Optimize processes for beta cell differentiation

Develop high-throughput phenotypic assays for iPSC-derived tissues

Perform preparation and analysis of samples for immunohistochemistry, flow cytometry and ELISA assays

Perform compound screens to correct diabetes phenotypes in iPSC-derived tissues

Maintain accurate and complete records and protocols

Communicate in written and oral form with a multidisciplinary team

Work with the NYSCF Global Stem Cell ArrayTM team to automate methods for iPSC differentiation

Oversee and participate in the planning, design, and execution of experiments

Lead novel assay/process development in emerging areas of interest for future work

Provide technical support and mentorship to junior scientists

What we’re looking for:

Recent PhD in Biology, or another relevant field

Experience with human pluripotent stem cells, including directed differentiation

Experience with directed differentiation towards the pancreatic lineage is a plus

Experience with pluripotent stem cell-based disease modeling is a plus

Experience with automation systems is a plus

Ability to analyze and interpret data and report findings succinctly

Demonstrated ability to work both independently and within a multidisciplinary team

Excellent written, verbal and interpersonal communication skills

Adaptability to work in a fast-paced and changing environment

Experience using a LIMS system is a plus

Full Time

At NYSCF, we believe diversity in all forms makes us a better team, and we celebrate it. Yet studies have shown that women, people of color, and other minoritized individuals in STEM may be less likely to apply to jobs where they do not meet all of the criteria. Therefore, if you are excited about this role but your past experience does not align perfectly with every qualification in the job description, we encourage you to apply anyways. You may be just the right candidate for this or other roles. We offer all full-time employees a comprehensive benefits package that goes into effect on the first of the month following your start date. It includes a choice of medical, dental, and vision insurance (with 100% of the premiums paid for employees and subsidies for any dependents), 403b retirement plan with 5% employer match (immediate vesting schedule which starts after your first 90 days), short and long term insurance, life insurance, inclusive paid parental leave program, pretax transit and parking, legal aid benefits and wellness benefits. Our paid time off includes vacation, sick, personal days, flexible holidays, summer flex program, and all company holidays. If a visa is required, NYSCF will cover all of those costs. Relocation will sometimes be necessary; therefore, we will provide you with an allowance. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and complete the required employment eligibility verification upon hire. NYSCF is an equal opportunity employer, and we value diversity in our organization. We provide equal opportunities to all applicants for employment without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, veteran status, or any other characteristic protected by law. The position is based at our location in Manhattan. Recruitment Phishing Scams: Fake job advertisements and offers are increasingly appearing on the internet. If you have encountered a job posting or have been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond and report it to the Federal Trade Commission and the FBI at can also contact our team to report details of your experience. Please be mindful of the following: · NYSCF will only reach out to you through an “@nyscf.org” email address. · Other than your email address or telephone number, which you may provide via a job application portal, NYSCF will never ask you to provide personally identifiable information about yourself (such as a Social Security Number or Driver’s License Number) via a messaging application (like that used on the LinkedIn platform or Microsoft Teams or Zoom). · NYSCF will conduct interviews face-to-face over Zoom or in person. · All job postings will be listed on NYSCF's official career page (nyscf.org/careers). If someone contacts you about a job or position that is not listed on the official career page, please contact the NYSCF recruitment team at the contact information below. · If you have any questions regarding the validity of a recruitment inquiry or an interview, please contact the NYSCF’s recruitment team at to confirm before proceeding.