Director of MS&T - Cell Therapy

At AstraZeneca, we turn molecules into medicine. We are unified in our commitment to deliver more medicines to more patients more quickly. Our role in Operations is to bring promising therapies from the lab to life through a rigorous process of development, manufacturing, testing, and supply. We are looking for a Director of MS&T to join our fast-paced, growing environment at our cell therapy facility in Rockville, Maryland. This is a unique opportunity to make a direct contribution and immediate impact on patients by delivering life-saving cell therapies.

As the Director, you will provide technical directions and leadership to cell therapy manufacturing scientists.

What you will do:

Your responsibilities will include new product introduction into the site, process and productivity improvement, new technology evaluation and implementation, predictive data analytics, advanced CPV, and manufacturing process support.

Responsible for multiproduct cell therapy manufacturing processes and enhancing value to patients, planet, process, and people.

Building and handling a high-performing team of scientists and engineers including early talent development through interns, co-ops, and global graduates.

Ensure successful technology transfer, scale-up to commercial facilities, and process validation of new products into the site.

Drives process and productivity improvements in manufacturing processes in line with regulatory requirements and business objectives.

Authors, reviews, and approves CMC documentation for health authority responses and for regulatory filings.

Monitors and improves process performance of products manufactured at the site. Works with the functional manager to develop and implement enhanced tools and capabilities for ongoing process monitoring and trending.

Minimum Qualifications:

Bachelor's degree in a relevant field.

Minimum 10 years in biologics drug substance manufacturing.

Proven leadership skills with experience managing a team of scientists.

Experience with process analytical technologies, predictive analytics, and advanced Chemometrics.

Preferred Qualifications

Experience with cell therapy processes and automated technology.

Experience with Lean methodologies.

Proven track record of enhancing process productivity.

At AstraZeneca, we invest in internal capabilities to help us realize our ambition to discover and deliver next-generation cellular therapies. We are uniquely positioned to develop cutting-edge technologies to advance cell therapies in the treatment of disease areas with high unmet medical needs. Our fast-paced, growing environment provides a wealth of opportunity and global opportunities to learn from other teams, embrace lifelong learning, and build capabilities, setting your direction and pace for your long-term career.

Are you ready to pioneer a Lean mindset to drive greater quality and safety? Join us at AstraZeneca and be part of leading our Operations function at an exciting time of growth and evolution. We are looking for inspiring and credible leaders who are true team players. If you want to develop, this is the place for you. Apply now

Date Posted10-May-2024

Closing Date26-May-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

R-199451