Mass Spectrometry Lab Technician

About AOA Dx Inc.

AOA Dx is developing the next frontier in early-stage cancer detection through its pioneering work in glycolipids and proprietary biomarker technology. Our revolutionary tumor marker ganglioside platform, GlycoLocate™, is paving the way for life-saving early cancer detection. In a first of its kind, AOA Dx is developing AKRIVIS GD™, an early-stage liquid biopsy test for ovarian cancer.

Mass Spectrometry Lab Technician (Contract)

This is an exciting opportunity to work with a dynamic start-up company. The Lab Technician is responsible for carrying out reagent and assay development activities in the laboratory, working to achieve development project goals including data analysis and assay qualification. This is a laboratory position performing immunoassays on a routine basis with relatively high throughput (3-10 plates per day). A high degree of professional attitude, creativity and self-management is expected.

Responsibilities

Prepare and extract samples for analysis.

Operate and maintain HPLC-MS instruments.

Troubleshoot instrument issues and perform routine maintenance.

Design and execute experiments involving sample analysis using mass spectrometry techniques.

Contribute to development and optimization of analytical methods.

Present data in a clear, concise, and understandable manner.

Participate in general lab maintenance including maintaining laboratory supplies and equipment.

Prepare, maintain, and report reagent inventories for assigned methods.

Utilize self-reliance in understanding and adhering to laboratory safety precautions and proper use of personal protective equipment.

Some projects require running assays with Biosafety Level 2 (BSL-2) samples such as human serum and plasma.

Specific duties may vary.

Experience and Qualifications

Bachelor’s or Master’s Degree in chemistry, biochemistry, cellular/molecular biology, biotechnology, or other related science is highly preferred. Additional experience may be substituted.

Minimum of 2+ years of hands-on experience operating and maintaining an HPLC-MS system and running -omics experiments (lipidomics, metabolomics or proteomics)

Knowledge of biological sample preparation and extraction techniques for downstream LC-MS analysis

Desirable skills/tools may include but are not limited to:

5+ years of general laboratory experience.

Experience working with glycolipids is preferred.

Working knowledge of lipid chemistry.

Training and experience with Biosafety Level 2 (BSL-2) techniques is preferred.

Knowledge, Skills and Abilities

Strong scientific fundamentals and analytical background.

Logical problem solving and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion.

Independently execute assay and reagent troubleshooting, optimization and validation experiments.

Excellent oral, written communication and interpersonal skills.

Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data.

Experience with standard data analysis tools (Excel) and the quantitative background to advance this knowledge on the job is expected.

Physical Demands:

Up to 75 % of the day may be spent at a lab bench.

Ability to lift up to 25 lbs.

AOA Dx offers competitive benefits, including unlimited PTO, group health, dental, and vision insurance, 100% employee sponsored life and disability benefits, monthly cell phone reimbursement, and a 401k plan with employer match.

Salary Range: $25 - $35/hour commensurate with education and experience

Location: On-Site Denver, CO

AOA Dx is an equal opportunity employer and welcomes candidates from all backgrounds to apply.