Senior Scientist

Are you a motivated and dynamic medicinal chemist ready to make an impact in drug discovery? We're actively searching for a talented individual to join our team and take charge of discovering, characterizing, and optimizing small molecules.

As part of our team, you'll collaborate closely with senior staff and Contract Research Organization (CRO) partners to drive our research forward. Your role will involve overseeing a dedicated chemistry team, providing guidance, and meticulously reviewing data to ensure the quality and progress of our projects.

Responsibilities:

Develop and utilize a deep knowledge of medicinal chemistry and drug discovery principles to advance portfolio projects from inception to the selection of development candidates

Create optimization strategies for improving lead series physiochemical properties, in vitro ADME, and PK via hypothesis-driven medicinal chemistry design principles.

Work closely with biology and chemistry colleagues to develop hypotheses that address key drug optimization goals and design novel compounds testing those hypotheses.

Create intellectual property that advances portfolio projects. Prepare and update patent applications to protect the lead series.

Prepare and present summaries of work for department and project meetings.

Coordinate activities with outside partners and CROs; help maintain corporate database; prepare and deliver internal presentations, patent applications, and external publications as driven by the project and corporate strategies.

Experience:

Ph.D. in Chemistry or related fields with significant background in organic synthesis, with a minimum of 0-5 years of industrial experience

A track record of synthetic productivity and problem-solving, as demonstrated by patent applications, publications, and presentations

Ability to apply the principle of physical organic chemistry to rationalize reaction mechanisms and molecular interactions

Demonstration of outstanding communication skills through internal/external presentations and publications

Flexibility in adapting methods/skills according to evolving priorities

The ability to work within a fast-paced matrixed team of experts and scientific associates

Knowledge and Skills:

Expertise in multi-step organic synthesis and purification of small molecules

Expertise in small molecule characterization, including LCMS, NMR, and MS

Education:

Ph.D. in chemistry or medicinal chemistry