Senior Research Associate, Pharmacology/Toxicology, Gene Therapy

Senior Research Associate, Pharmacology/Toxicology, Gene Therapy

Who We Are

Rampart Bioscience is an early-stage biotechnology company pioneering a new class of medicines for individuals, especially children, living with genetically driven diseases.

Powered by its non-viral DNA delivery platform, Rampart’s mission is to develop transformative medicines that achieve higher standards for potency and safety than current gene therapies. Rampart is funded by several global, top-tier healthcare investment firms, and is led by seasoned experts in gene delivery, protein sciences, and clinical translation.

When you join Rampart, you are not simply advancing your career. You are joining a team that is dedicated to realizing the potential of gene therapy to provide effective, safe, and long-lasting treatments for a wide range of diseases. We are mission-driven and guided by our values:

· People first. Nothing shall be done to harm human dignity or get in the way of one’s freedom.

· Unbound by convention. We embrace the unfamiliar and are willing to stand alone together.

· Actions speak. We have a bias for action and serve with humility as we work to achieve new ground.

· Relationships matter. We build authentic relationships founded on trust, integrity, diligence, and honor.

· We care. We are disciplined and passionate. We love what we do, who we do it with, and who we do it for.

As we advance our work in exciting ways, we are selectively hiring talented team members to join us in our Southern California locations. For more information, please visit

About the Job

In this role, the successful candidate will partner with the Pharmacology/Toxicology team to provide support for in vivo rodent studies.

This role requires a high level of organization and capacity to coordinate and execute multiple experiments. Under minimal supervision, he/she will provide skilled handling of laboratory animals in a safe and sanitary manner as required for the conduct of studies, including activities related to dosing, sample collection, necropsy, imaging, and/or behavioral assays and /or data compiling. The candidate will ensure that activities performed are in compliance with study plans and with all standards set forth by NIH and USDA as well as the IACUC and Company standards.

The ideal candidate will have broad in vivo mouse experience, a collaborative spirit, a sense of urgency, and a desire to work in a fast-paced startup environment.

Key Responsibilities

Perform procedures such as injections (IV, IM, IP, SC, HD, Neonatal) in mice, monitor animal health, collect blood through multiple routes, and collect tissues.

Assist in developing or writing study and IACUC protocols.

Assist in developing and performing phenotype scoring and biomarker/behavioral assays.

Assist in developing and performing specialized procedures, such as radiographic or micro-CT imaging.

Lead colony management activities, including breeding, weaning, animal identification (ear-tagging or alternative ID methods), and maintaining accurate colony populations.

Perform and interpret genotyping assays.

Coordinate resources (staff, animals, equipment, supplies) when leading a study to ensure technical and logistical success of study conduct.

Maintain a detailed, accurate, and up-to-date electronic laboratory notebook, controlled substances log, and sample inventory database, as needed.

Assist in lab organization and maintenance, sample inventory management, and supply ordering.

Train junior staff as needed.

Qualifications/Requirements

BS degree and 3-5 years of relevant animal handling and care experience.

Ability to work directly with mice and willingness to participate in Occupational Health Program, as required for facility entry.

Skill in handling, restraint, identification, and sexing of laboratory mice.

Experience with multiple administration (IV, IP, SC, and PO) and collection routes.

Ability to work evenings, weekends or holidays, as needed.

Desirable Skills and Experience

Expertise working with a variety of in vivo animal models; genetic disease models a plus.

A high degree of attention to detail and concern for animal well-being.

Ability to troubleshoot and think analytically.

Strong work ethic and a collaborative team player.

Good interpersonal skills and effective communication, both verbal and written.

Ability to multitask and support multiple projects simultaneously.

A strong sense of urgency and accountability.

Compensation, Benefits & Additional Information

Compensation range: $78,000 - $90,000 commensurate with experience and qualifications.

We are proud to provide a robust benefits package for our employees, including:

· Medical, dental and vision insurance for employees and their dependents, with a 90% - 100% company contribution.

· Life, AD&D and disability insurance for employees, with a 100% company contribution.

· 401(k).

· Generous amounts of paid time off through our vacation, holiday, sick and floating time off programs including floating “beach” days and your birthday off.

· Ability to participate in the company’s Stock Benefit Plan and annual Bonus Plan.

Rampart Bioscience is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, disability, age, veteran status or any other applicable legally protected characteristics.Industry

Biotechnology ResearchEmployment Type

Full-time