Main Duties and Responsibilities
This job is a lab-based research role.
The work will be focused heavily upon molecular viral surveillance and resistance monitoring for the AZ infection franchise.
A background in molecular/clinical virology and/or vaccinology is required
• Rescue and characterize pseudoviruses and/or RNA viruses
• Apply molecular biology skills to generate recombinant proteins and viruses
• Execute biochemical and cell-based assays to characterize candidate or authorized vaccines and mAbs for SARS-CoV-2, RSV, and other viral pathogens
• Assist in the preparation and review of bioanalytical data and reports suitable for regulatory submission
• Communicate across the matrixed team environment
Education & Experience Requirements:
Bachelor's Degree in virology, molecular biology, immunology, or another related field with 2+ years of relevant industrial (preferred) or academic experience or a Master's Degree with some relevant experience.
Essential Requirements
• Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
• Experience in cell culture, viral propagation, and viral titration.
• Ability to evaluate data quality, troubleshoot, and interpret experimental results
• Meticulous tracking and documenting of results in laboratory notebooks, databases, and scientific reports
• Strong verbal and written communication skills
Desirable Requirements
• Hands-on experience with paramyxoviruses and coronaviruses
• Understanding of molecular cloning techniques and vector engineering
• Understanding of DNA sequencing techniques (NGS and Sanger) and sequence analysis
• Experience in the handling/processing of clinical specimens