Research Associate 2 MS

Research Associate Position

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The RA will assist the PI in conducting two projects. One project is studying the effects of certain drugs on bone loss in ovariectomized mice. This will require the ability to perform survival ovariectomy surgery in mice. In addition, it will require the ability to inject unanesthetized mice and to harvest tissues from mice post-mortem.

A second set of experiments involves examining the transcription factors induced by cytokines in osteoclasts that participate in the transcriptional regulation of the gene, sphingosine-1-kinase. This requires familiarity with cell culture, including isolating primary murine bone marrow cells. It also requires expertise in performing Western blots and electrophoretic mobility shift assays. Finally, knowing how to perform PCR and RT-PCR is required.

Facility with MS Word, Excel, Prism, and PowerPoint would be important.

Required Skills and Abilities

1. Ability to perform mouse survival surgery.

2. Ability to inject unanesthetized mice.

3. Ability to perform cell culture.

4. Ability to perform PCR and RT-PCR.

Principal Responsibilities

1. Designs, plans, implements and evaluates complex multifaceted research projects/systems, including method development, adaptation and validation.

2. Collaborates with PI to define research endeavors and the development of research hypothesis and approach.

3. Solves complex methodology, protocol, procedural and research problems through design of techniques, procedures and policies that will achieve research goals.

4. Develops long range plans for supplies and equipment to ensure smooth operation of laboratory.

5. Investigates, analyzes and evaluates complex data, data collection systems and methods to reach scientific conclusions and ensures the integrity of research data.

6. Collaborates with PI to coordinate major lab renovations working with Facilities, Health and Safety, and Purchasing to ensure deadlines, safety standards and purchases are according to plans and within budgets.

7. Prepares scientific reports and papers for research proposals and published reports.

8. May perform other duties as assigned.

Master's Degree in a scientific discipline and three years of experience or an equivalent combination of education and experience.