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Senior Program Manager

Company:
Landmark Bio
Location:
Watertown, MA, 02472
Posted:
May 23, 2026
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Description:

We are seeking a self-driven, team-oriented, and entrepreneurial-minded Senior Program Manager to join Landmark Bio. The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a functional understanding of the technical aspects of cell and gene therapy programs and awareness of Landmark Bio's business objectives.

The Senior Program Manager will support cross-functional program execution by driving operational coordination, maintaining program management tools and documentation, and serving as a key liaison between internal teams and external clients. This role is responsible for managing timelines, dashboards, communications, and process improvements while ensuring programs are executed efficiently and effectively.

Responsibilities

Support the planning, coordination, and execution of internal and client-facing programs

Develop and maintain program timelines, schedules, dashboards, and risk registers with support from senior program managers

Coordinate program materials and shared resources, escalating constraints and risks as appropriate

Generate and maintain documentation for program scope changes and client communications

Assist with capturing and sharing lessons learned across programs to improve operational efficiency

Create and update presentations for team meetings, leadership reviews, and client discussions

Serve as a Smartsheet super user for the organization, creating, managing, and optimizing complex workflows, automations, dashboards, and reporting tools

Develop and maintain program management resources including trackers, templates, dashboards, presentation materials, and other operational tools

Evaluate and recommend process improvements to enhance team collaboration, visibility, and efficiency

Collaborate cross-functionally on new system evaluations, tool implementations, and training initiatives

Maintain internal Microsoft Teams sites and external SharePoint client sites to ensure documentation is organized, current, and accessible

Archive program documentation at the close of programs in accordance with internal procedures

Own and maintain program management documentation including:

Program charters

Program plans and schedules

RACI matrices

Risk registers

Business requirements

Policies and procedures

Training materials

Ensure all documentation is accurate, complete, version-controlled, and properly stored

Serve as the primary point of contact for assigned clients

Coordinate and manage client meetings, teleconferences, and onsite visits

Prepare agendas, meeting minutes, action items, and follow-up communications

Build collaborative relationships with internal stakeholders and external partners to support successful program delivery

Assist in training personnel on evolving program management tools and systems

Develop training materials including slide decks, guides, and reference documentation

Qualifications

BS degree with 7+ years relevant experience (GMP pharmaceutical, biologics, and/or cell and gene therapy field) is required

PMP certification desired

High degree of proficiency in Smartsheet is required, including advanced skills in workflow design and implementation, template creation and management, user training and support, and reporting and analytics

Strong communication, problem solving, planning, and project management skills

Ability to support more than one project of a reasonable size simultaneously

$140,000 - $165,000 a year

Landmark Bio is dedicated to translating cutting-edge research into life-changing therapies. The company provides CMC development and GMP manufacturing capabilities for cell and gene therapies and other novel modalities, and partners with academic, biotech, and industry collaborators to advance next-generation manufacturing technologies.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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