Mechanical Engineer, Early Research and Development

Senior Mechanical Engineer Senior Mechanical Engineer / Biomedical Engineer Resource Type: W2 Only Pay Rate: $71/hr Location: On-site - Santa Clara, CA About Roche A healthier future drives us to innovate, continuously advance science, and ensure access to healthcare for all.

At Roche, we are building a world where people have more time with those they love.

We are advancing next-generation sequencing (NGS) by simplifying workflows, accelerating clinical research, and expanding access to genomic data.

Our integrated solutions span from sample preparation to sequencing and bioinformatics-delivering a seamless "sample in, result out" experience.

Role Overview The Systems Technology Group within Roche Sequencing Solutions is seeking a Senior Mechanical Engineer to design and develop advanced sequencing systems.

This is a hands-on, multidisciplinary role focused on solving complex mechanical challenges involving electro-mechanical, pneumatic, thermal, and fluidic systems.

Core Responsibilities * Design and develop mechanical sub-systems including electro-mechanical, pneumatic, fluidic, and thermal components * Collaborate cross-functionally with electrical, materials, and consumables teams * Develop mechanisms for automated reagent and flow cell handling * Design and implement thermal control systems * Lead subsystem integration, verification, and troubleshooting * Drive design reviews and resolve technical trade-offs * Manage timelines and technical deliverables * Create and maintain CAD models, drawings, and specifications * Contribute to system architecture and technical strategy * Present technical updates and engineering decisions to stakeholders Required Qualifications * PhD + 1 year, OR Master's + 2 years, OR Bachelor's + 4 years of relevant experience * Strong expertise in mechanical and electro-mechanical system design * Experience with thermal management and precision temperature control * Hands-on experience with fluidics systems (pumps, valves, sensors, tubing) * Proficiency in 3D CAD tools (e.g., SolidWorks) * Experience with manufacturing processes (machining, injection molding, 3D printing) * Strong troubleshooting skills across hardware, software, and chemistry interfaces * Hands-on experience with machine shop tools and prototyping technologies * Familiarity with Python, LabVIEW, or similar tools Preferred Qualifications * Experience with simulation tools (CFD, FEA) * Background in NGS or genomics instrumentation * Experience in regulated product development environments * Strong communication and interpersonal skills * Ability to manage multiple priorities effectively Additional Information * This is a fully on-site role in Santa Clara, CA * No relocation assistance is provided * No requirement for fluidics/microfluidics specialization, but life sciences instrumentation experience is preferred #LI-MB1