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Senior Software Developer

Company:
Guidehouse
Location:
North Bethesda, MD, 20852
Pay:
54.33 - 90.38 per hour
Posted:
February 23, 2026
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Description:

Job Family:Software Development & Support

Travel Required:Up to 10%

Clearance Required:Ability to Obtain Public Trust

We are seeking a highly skilled, dynamic developer with full stack expertise using Python and JavaScript technologies. The developer will support web and mobile applications used by researchers and clinicians at the National Institute of Allergy and Infectious Diseases (NIAID) in the National Institutes of Health (NIH). This opportunity is a full-time position with Guidehouse and can be remote or on-site at NIH in Rockville, MD.

The Senior Software Developer will collaborate closely with PhD-level scientists and subject matter experts to translate complex scientific workflows into reliable, scalable services and to design user interfaces that make complex scientific data and workflows accessible and actionable. Responsibilities include designing and implementing APIs, data processing pipelines, and computational services, developing reusable React components, integrating with APIs, ensuring performance and usability at scale, contributing to system architecture, writing well-tested, maintainable code, and mentoring other developers. Experience with scientific computing libraries, data-intensive workloads, or distributed systems is highly desirable. Applications developed by the team are used in clinical and research settings and development is driven by continued use and iterative feedback from researchers and clinical staff as well as subject matter experts and software development team members. Strong communication skills for this position are essential as the Developer may need to frequently converse with non-computational subject matter experts.

What You Will Do:

The role will be responsible for creating and maintaining applications and will entail:

Participate in a highly integrated software development team working in an agile environment, documenting code, testing code, and tracking tasks

Develop new applications as well as extend existing applications; develop new features and customizations that harmonize with existing codebases

Find creative solutions to scale the performance of existing analysis pipelines to meet the demands of rapidly growing datasets

Collaborate between the project team and internal teams to support enterprise infrastructure to deploy and maintain software

Experiment with new technologies and systems as well as prototype solutions for potential integration into existing infrastructure

Review and address security vulnerabilities in collaboration with our security and infrastructure teams

What You Will Need:

M.S. in computer science or related field

Key technologies: React, TypeScript/JavaScript, Python, Docker, AWS (e.g., ECS/EKS, S3, RDS), CI/CD pipelines with GitHub Actions

Experience/Skills

6+ years of Full stack web application development and maintenance experience, including development in Python and React

3+ years of experience working with databases

Experience building containerized applications using Docker

Experience using GitHub actions

2+ years of experience with Git and code deployments to multiple environments and involving reviewing the contributions of multiple team members

Experience deploying and operating software on AWS

Experience mentoring other developers and reviewing and providing feedback on other developer’s work

Experience developing and using RESTful web services and JSON or XML objects for communication

Experience communicating with end users on software development projects; being comfortable explaining complex computational terms using simple language for a non-computational audience

Demonstrated experience extending the functionality of existing software; ability to learn an existing body of code and extend it

Must be able to OBTAIN and MAINTAIN a Federal or DoD "PUBLIC TRUST"; candidates must obtain approved adjudication of their PUBLIC TRUST prior to onboarding with Guidehouse. Candidates with an ACTIVE PUBLIC TRUST or SUITABILITY are preferred.

What Would Be Nice To Have:

Knowledge of terraform

Familiarity with SCRUM/Agile development

Familiarity with Swagger/OpenAPI

Experience visualizing complex or large-scale data sets

Experience reviewing and responding to security vulnerability reports

Background in bioinformatics, genomics, or computational biology

The annual salary range for this position is $113,000.00-$188,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

Medical, Rx, Dental & Vision Insurance

Personal and Family Sick Time & Company Paid Holidays

Parental Leave

401(k) Retirement Plan

Group Term Life and Travel Assistance

Voluntary Life and AD&D Insurance

Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

Transit and Parking Commuter Benefits

Short-Term & Long-Term Disability

Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

Employee Referral Program

Corporate Sponsored Events & Community Outreach

Care.com annual membership

Employee Assistance Program

Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at or via email at . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or . Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact . Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

Full-Time

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