Training Medical

DAVID E. WHITE, Ph.D.

**-** ***** ******

Fresh Meadows, NY 11366

Personal Phone: 215-***-****

Email: **************@*****.***

LinkedIn: http://www.linkedin.com/pub/david-white/33/a08/676

SKILLS: • Excellent writing skills, AMA style (numerous grants and manuscripts)

• Strong communication skills

• Leadership skills (President of Postdoctoral and Doctoral trainees)

• Relational knowledge

• Assay development

• Established collaborations with other researchers and acted as liaison between groups

• Knowledge of scientific databases

• Analysis of large data sets (microarray, ChIPseq)

• Computer skills (MS Office, Adobe Photoshop)

RELEVANT EXPERIENCE: I have had over six years grant writing experience in academia and in industry. I have designed, drafted, and submitted proposals on a wide range of topics including chondrogenesis, magnesium homeostasis, the DNA damage response, drug development (SBIR/STTR), and aging.

2012-present Consultant for Longevica Pharmaceuticals.

2011-2012 Medical writer/scientist at Longevica Pharmaceuticals working with the President/Founder of the company to design, draft, and submit grant proposals for the company and for his academic research laboratory.

2005-2011 Postdoctoral fellow at the Wistar Institute working with Dr. Frank J. Rauscher III, studying the regulation of KAP1 during the DNA damage response and the role of KAP1 in establishing the epigenetic landscape that facilitates multipotency.

1997-2005 Graduate Student at CUNY-Hunter College working with Dr. Jill Bargonetti, studying DNA damage pathways and the regulation of p53.

1995-1997 Laboratory Technician for Dr. Jill Bargonetti at CUNY-Hunter College

EDUCATION:

1997-2005 The City University of New York Graduate Center

Doctor of Philosophy (Molecular Biology)

1997-2000 The City University of New York Graduate Center

Master of Philosophy (Molecular Biology)

1991-1995 Rochester Institute of Technology

Bachelor of Science (Biotechnology)

PUBLICATIONS:

Abrams, C.S., Wu, H., Zhao, W., Belmonte, E., White, D., and Brass, L.F. (1995) Pleckstrin inhibits phosphoinositide hydrolysis initiated by G-protein-coupled and growth factor receptors. Journal of Biological Chemistry 270 (24):144**-*****.

Bargonetti, J., Chicas, A., White, D., and Prives, C. (1997) p53 represses Sp1 DNA binding and HIV-LTR directed transcription. Cell, and Mol, Biol. 43: 935-949.

Xiao, G., White, D., and Bargonetti, J. (1998) p53 binds to a constitutively nucleosome free region of the mdm2 gene. Oncogene. 16: 1171-1181.

Abbas, T., White, D.E., Lui, L., Yoshida, K., Foster, D., and Bargonetti, J. (2004) Inhibition of human p53 basal transcription by downregulation of Protein Kinase C Delta. Journal of Biological Chemistry 279 (11) 9970-9977.

Arva, N.C., Gopen, T.R., Talbott, K.E., Campbell, L.E., Chicas, A., White, D.E., Bond, G., Levine, A.J., and Bargonetti, J. (2004) A chromatin associated and transcriptionally inactive p53-MDM2 complex occurs in mdm2 SNP309 homozygous cells. Journal of Biological Chemistry 280 (29-267**-*****.

White, D.E., Talbott, K.E, and Bargonetti, J. (2006) Mdm2 associates with chromatin only in the presence of p53 and is released to facilitate activation of transcription. Cancer Research 66 (7) 3463-3470.

White, D.E., Negorev, D., Peng, H., Ivanov, A.V., Maul, G.G., and Rauscher, III, F.J. (2006) KAP1, a novel substrate for PIKK family members, co-localizes with numerous damage response factors at DNA lesions. Cancer Research 66 (24): 115**-*****.

Boamah, E.K., White, D.E.*, Talbott, K.E., Arva, N.C., Berman, D., Tomasz, M., and Bargonetti, J. (2007) Mitomycin-DNA Adducts Induce p53-Dependent and p53-Independent Cell Death Pathways. ACS Chem Biol. 2 (6): 399-407. (*co-first authorship)

Ivanov, A.V., Peng, H., Yurchenko, V., Yap, K., Negorev, D.G., Fredericks, White, D.E., W.J., Maul, G.G., Sadofsky, M.J., Zhou, M.M., and Rauscher III, F.J. (2007) PHD Domain-Mediated E3 Ligase Activity Directs Intramolecular Sumoylation of an Adjacent Bromodomain which is Required for Gene Silencing. Mol Cell 28 (5): 823-37.

Hou, Z., Peng, H., White, D.E., Negorev, D.G., Maul, G.G., Feng, Y., Longmore, G.D., Waxman, S., Zelent, A., Rauscher III, F.J. (2010) LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proc Natl Acad Sci 2010 107 (7):2938-43.

Hou, Z., Peng, H., White, D.E., Wang, P., Lieberman, P.M., Halazonetis, T., Rauscher III, F.J. (2010) 14-3-3 binding motifs in Snail are essential for Snail-induced epithelial mesenchymal transition. Cancer Research 70 (11):4385-93.

White, D.E., Rafalska-Metcalf, I.U., Ivanov, A.V., Corsinotti, A., Peng, H., Lee, S.C., Trono, D., Janicki, S.M., Rauscher III, F.J. (2012) The ATM substrate KAP1 controls DNA repair in Heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation. Mol. Cancer Res. 10(3):401-14.

White, D.E., Corsinotti, A., Mutyaba, P.L., Schultz, D.C., Peng, H., Hankenson, K.D., Trono, D., and Rauscher III, F.J. KRAB-ZFP/KAP1 Mediated Gene Silencing Contributes to the Maintenance of Multipotency. (submitted to Mol. Cell. Biol.)

Hawkins, A.J., Golding, S.E., Akopiants, K., White, D.E., Rauscher III, F.J., Povirk, L.F., and Valerie, K. ATM is Required for High-Fidelity DNA Repair by Nonhomologous End-Joining. (In preparation)

White, D.E. and Ryazanov, A.G. The role of channel kinases in the regulation of magnesium homeostasis. (In preparation for Nature Reviews)

ACADEMIC AND PROFESSIONAL HONORS:

2010-present Member of the American Medical Writers Association

2010-2011 Member of the Advocacy Committee of the National Postdoctoral Association

2007-2010 President of the Wistar Institute’s Postdoctoral Association

2007-2010 Postdoctoral Representative on the Wistar Training Committee

2007-2010 Individual Ruth L. Kirschstein National Research Service Award Fellowship (F32)

2008 Postdoctoral Representative for the Regional Postdoctoral Symposium

2006-2007 The Wistar Institute’s NCI Cancer Biology Postdoctoral Training Grant (T32)

2008-present Member of the American Association for Cancer Research

2007-present Member of the National Postdoctoral Association

2001-2002 Molecular, Cellular & Developmental Biology Committee

2000-2001 Graduate Center Executive Committee Member

1999-2002 Graduate Student Association President

PAST SUPPORT:

2007–2010 The National Institutes of Health

National Cancer Institute

Ruth L. Kirschstein National Research Service Award Fellowship

F32 CA 126283-01

2006-2007 NCI Cancer Biology Postdoctoral Training Grant (T32)

The Wistar Institute

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