Dr.

XIAOCHUN LU, Ph.D.

*** ******** **., ****** ****, NC 27516

Phone: 269-***-**** (cell); 919-***-**** (home)

Email: **********@*****.***

Professional Overview

• PhD in molecular biology & biochemistry with strong cell culture and cell based assay background.

• Intensive cell culture experience including MSCs, dendritic cells, T cells, primary cells and tumor cell lines with expertise in cell identification using surface marker immunostaining and flow cytometry.

• Experienced in drug discovery industry with extensive knowledge in GLP regulation and SOPs writing.

• 6 years of experience in mechanical engineering department working with different instruments and mechanical systems with strong ability for mechanical system design, setup and operation.

• Experienced in molecular diagnosis development with broad molecular biology and immunology skills.

• High self-motivated, good oral and written communication skills, strong creativity and problem-solving ability, great team player, excellent interpersonal skills, good computer skills.

Professional Experience

SENIOR RESEARCH SPECIALIST

Division of Laboratory Animal Medicine (DLAM), UNC-Chapel Hill April 2010-Jun 2012

Responsibilities: bioassays development & validation under GLP; molecular diagnostic lab setup & management; lead NIH RO1 “Inflammation and Platelet Activation in Cardiovascular Health Disparities”.

SCIENTIST/TRAINED STUDY DIRECTOR

Experimental Therapeutics (ET), MPI Research, Inc. USA July 2008-April 2010

Responsibilities: immunoassay & biochemical assays development under GLP; human disease animal model development & validation; drug efficacy, PD, PK & toxicity study under GLP regulation; project management.

RESEARCH SCIENTIST/POST-DOC

Duke University School of Medicine Jun 2002 – July 2008

Responsibilities: conducted research on novel proteins function in Akt-MSC stem cell therapy for cardio protection; in vitro pulsed immunocytes and dendritic cells mediated immunotherapy for b16 melanoma, transgene expression analysis using real time PCR.

RESEARCH SCIENTIST/PHD FELLOWSHIP

Cardiovascular Research Institute, Peking University Aug 1998 – Jun 2002

Responsibilities: conducted research on gene therapy for EPO-dependent renal anemia and ischemia.

R&D SCIENTIST/ASSOCIATE DIRECTOR

Guilin South Biotechnology, Inc. Nov 1994 – Aug 1998

Responsibilities: conducted drug discovery research on therapetic novel proteins for cardiovascular diseases; biochemical assays and immunoassays development and validation; diagnostic lab management.

SCIENTIST (FERMENTATION & QC)

Guilin Jiqi Pharmaceutical Group, Inc. July 1991-Nov 1994

Responsibilities: fermentation support and QC for antibiotics manufacturing; potency test & strain selection.

Publications (selected)

1. Pallav Bhatnagar, Xiaochun Lu, et al: Genetic variants in Platelet Factor 4 modulate inflammatory and platelet activation biomarkers. Circulation: Cardiovascular Genetics. Accepted on Jun 2012.

2. Xiaochun Lu, Georgy Sankin, et al: Activation of transgene expression in skeletal muscle by focused ultrasound. Biochemical and Biophysical Research Communications, 2009 Feb 6;379(2):428-33.

3. Yifei Xing, Xiaochun Lu, et al: The Effect of High Intensity Focused Ultrasound Treatment on Metastases in a Murine Melanoma Model. Biochemical and Biophysical Research Communications, 2008 Oct 31; 375(4):645-50.

4. Xiaochun. Lu and Pei. Zhong: “Ultrasound-induced cell detachment and gene transfection to adherent cells in vitro”. Acoustic Research Letter Online (ARLO), Vol: 6 (3), 195-200, July 2005.

6. Xiaochun Lu, Airu Zhou and Caike Jin. “The effects of electroporation-mediated erythropoietin (EPO) gene transfer into skeleton muscle on renal anemia”. Chinese Medical Journal (Zhong Hua Yi Xue Za Zhi), Vol.80 (3):222-5, Mar 2000.

7. Xiaochun Lu, et al: “IL-2 and tumor lysate pulsed T cells for tumor adoptive immunotherapy”. ACTA MEDICINAE SINICA (supplemental edition), 1996, Sept (03), 24-28

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