Dr. Sheetal R. B
*********@*****.*** Bangalore,
India,
Mobile:
Objective
Looking for Professional opportunity to work in an organization that gives me ample scope to apply my Technical knowledge, skill and capacity in the field of Intellectual property rights/ R & D, to provide right, economic and fast path for R & D activities and step forward in the growth of organization.
Academic profile:
Post Graduation Diploma in Intellectual Property Rights - 2011, from National Law School of India University, Nagarbhavi, Bangalore-560 242.
Ph. D. in Chemistry (Awarded, 2007)
Title: “Physico-chemical study of unusual fatty acids from minor-oilseeds and synthesis of oleochemicals: An approach to the biological evaluation”.
Karnatak University, Dharwad, Karnataka State, India
M. Sc. in Organic Chemistry, 2002-2004, Grade: First Class.
Karnatak University, Dharwad, Karnataka State, India
B. Sc. (CBZ), 1999-2002, Grade: First Class with Distinction.
K. C. P. Science and Arts College, Bijapur. Affiliated to Karnatak University, Dharwad, Karnataka State, India
Skills in Patent Analysis:
Patent searching, drafting, Indian procedure for filing up patents.
Computer Knowledge:
Chemistry software’s like SciFinder, STN, ISIS Draw, Chem. Draw, and Chem. Sketch. Working knowledge of MS Office, PowerPoint, and extensive internet usage for reference work.
Experimental and Instrumental Techniques:
Purification techniques like column chromatography, preparative thin layer chromatography. Good working knowledge of IR spectrophotometer. Characterization of the newly synthesized compounds by physical methods such as IR, 1H-NMR, 13C-NMR, Mass spectrometry and Gas chromatography.
Thesis Summary:
My research work involves natural product extraction as well as synthesis of oleochemical and their biological activity. The different plant seed oils were collected and extracted using Soxlet apparatus and further purified by different Chromatographic Methods such as Picric - acid thin layer chromatography, argentitation chromatography, Column chromatography. Further the peaks were identified by comparing their retention times with those of standard reference sample under the similar conditions in Gas chromatography. The various chemical tests like direct thin layer chromatography test, Halphen test, 2,4-dinitrophenyl hydrazine (2-4-DNPH) thin layer chromatography test, picric acid thin layer chromatography test were carried out for hydroxy, cyclopropenoid, keto and epoxy functional groups respectively. Analytical values of oils were determined according to AOCS methods (Iodine value and Saponification value). The chemical screening that revealed the natural sources of unusual fatty acids in several minor-oilseeds. The new and interesting unusual fatty acids present in high concentration in certain seed oils are being exploited for the industrial utilization.
The seed oils of Cleome icosandra, Celosia cristata, Prosopis specigera, Cassia tora, Vitex negundo, Ceiba pentendra and Swietenia humilis contain Cyclpropenoid fatty acid. The cyclopropenoid fatty acids have been characterized as 7-(2-octacyclopropen-l-yl)heptanoic acid (malvalic acid) and 8-(2-octacyclopropen-1-yl)octanoic acid (sterculic acid).
The unsaturated hydroxy fatty acids isolated from Cleome icosandra, Celosia cristata, Prosopis specigera, Cassia tora, Vitex negundo, Ceiba pentendra and Swietenia humilis seed oils have been characterized as 12- hydroxyoctadec-cis-9-enoic (ricinoleic) acid.
Synthetic part: involves synthesis of oleo-benzimidazole.
The present synthetic investigation describes the reaction of different substituted o- phenylenediamine, with different unusual fatty acids under microwave irradiation to yield novel oleo-benzimidazoles.
Further biological activity was carried out for both seed oils as well as newly synthesized oleochemicals. It was observed that most of the natural products showed a moderate activity against the different strains of bacteria and fungi. Oleo-benzimidazole derivatives showed good activity against the different strains of bacteria and fungi.
Apart from thesis work, Oleo-triazolo-thiadiazole, Oleo-pyrazzole were synthesized by thermal as well as by microwave irradiation. A comparative study of thermal process and microwave irradiation is under progress so that green chemistry concept becomes more focused in our research investigation and their biological activity is also carried out simultaneously.
Professional Experience: 6+ years of Experience:
Lecturer for P. G. Department of Organic Chemistry at Bangalore City College, Bangalore. Affiliated to Bangalore University. Since May 2009-till date.
Worked as Lecturer from June 2008 - April 2009, in Post Graduate Department of Organic Chemistry, Shri Tuljaram Chaturchand College, Baramati, Pune District, Maharashtra, Affiliated to University of Poona, Pune.
Worked as Guest Lecturer from August 2004-April 2006 in Post Graduate Department of Studies in Chemistry, Karnatak University, Dharwad.
Conferences Attended and Papers presented:
“Amido-imidol tautomerization by acid-catalyzed addition of dinitriles to oleic acid: A novel route for synthesis of N,N’Bis(1-carboxy-N-Heptadec-9yl)alkyl or aryl Diamides and biological importance and possible industrial utilization”, held at Mangalore University on may 13th and 14th 2006.
Cyclopropenoid fatty acids in Zanthoxylum limonella seed oil., held at Shankarghata, Kuvempu University, Shimoga on March 23 and 24th 2007.
DECLARATION:
I hereby declare that the above information is factually correct to the best of my
Knowledg.
Dr. Sheetal R. B