Software Engineer

Zhiqiang Lao

Phone: 609-***-****(cell)

Email: ****@*******.***

Citizenship: US citizen

Career Objective

A challenging R&D position in areas of Image Processing, Computer Vision, and Computer Graphics.

EXPERIENCES

10/2007 – now, CAD and image processing & analysis, Carestream Health Inc., senior algorithm scientist

• Lead algorithm development of breast tissue segmentation and quantification in mammography image.

• Lead algorithm development of architectural distortion detection in mammography image (delivered to product, the designed algorithm has significant improvement in detecting architectural distortion and spiculated mass in mammography image).

• Studied modality orientated image quality normalization and parameter optimization for digital mammography.

• Lead algorithm development of enhancement of pneumothorax in CR and DR chest images (delivered to product).

• Lead algorithm improvement of collimator detection in DR chest images (delivered to product).

• Inventor on three pending patent applications.

07/2002 – 08/2007, Section of Biomedical Image Analysis, University of Pennsylvania, Senior Research Investigator, and Research Associate

• Morphological feature based statistical shape analysis and classification based early detection of cognitive disorder using 3D brain MRI, including schizophrenia, MCI, dementia, etc. – novel CAD algorithm based on morphological features in discriminating very subtle difference between pathological and normal control population.

• Lesion detection and segmentation using multispectral 3D brain MRI, including diabetes lesion, ischemic lesion.

• Preprocessing techniques of 3D brain MRI, such as: bias correction, intensity normalization, enhancement, etc.

• Image processing based quantitative measurement in clinical related research using 3D brain MRI, clinical trials including longitudinal study of aging effect, statistical evaluation and visualization of population cognitive difference, children brain development, lesion properties and brain tissue change of diabetics patients before and after hormone therapy.

09/2000 – 06/2002, Center for Biomedical Image Analysis, Johns Hopkins University, Postdoc

• Statistical analysis of prostate cancer distribution and application to prostate cancer detection.

• Statistical shape information constrained skull stripping using 3D brain MRI.

• Image processing based quantitative measurement in clinical related research – longitudinal study of aging effect using 3D brain MRI.

10/1998 – 08/2000, Center for Graphics and Image Technology, Nanyang Technological University, Singapore, Research fellow

• Video based human animation – developed a method based on computer vision to determine 3D spatial locations of joints or feature points of human body from human motion video.

• A snake-based greedy algorithm for object tracking in video.

• Model-based approach to human recognition in video.

07/1997 – 10/1998, R&D Division, Siemens Shanghai Mobile Communications Ltd, senior software engineer

• Network management, network optimization, CCS7 VAT.

SKILLS

Programming Skills

MATLAB, C/C++, C#, Perl under UNIX, Windows, Linux.

Standards, Systems and Applications

XML, DICOM, etc.

EDUCATION

Johns Hopkins University, Postdoc, Department of Radiology.

Zhejiang University, PR China, Ph.D. of Computer Science & Engineering.

Zhejiang University, PR China, MS of Computer Science & Engineering.

Zhejiang University, PR China, BS of Engineering in Computer Science.

SELECTED RELATED PUBLICATIONS

Journal Papers:

• Z Lao, L Li, “Video-based approach to human animation”, Computer graphics forum, 3rd issue, vol. 19, 2000.

• Z Lao, Y Pan, “A knowledge representation model for video-based animation”, Chinese journal of CAD and computer graphics, vol. 10, no.4, 1998, pp.367-376.

• Z Lao, Y Pan, “A global optimization based video deformation method”, Chinese journal of computer engineering, vol. 23, no.5, sep 1997, pp.60-63.

• Z Lao, D Xu, Y Pan, “The application of multisource analogical generation in video-stream generation”, Chinese journal of computer science, vol. 24, no.3, 1997.

Conference Papers:

• Z Lao, L Li, “Video-based approach to human animation”, Eurographics 2000, Interlaken, Switzerland, 20-25 Aug 2000.

• Z Lao, L Li, “A three-step to object tracking”, CVPRIP’2000, Feb. 27-Mar 3, 2000, Atlantic City, USA.

• Z Lao, L Li, “Model-based approach to human recognition”, CVPRIP’2000, Feb. 27-Mar 3, 2000, Atlantic City, USA.

• Z Lao, L. Li, "Multi-modal Edge Extraction from Motion Video", Proc. of 2nd International Conference on Information, Communications & Signal Processing (ICICS'99), December 7-10, 1999, Singapore.

Patent applications:

• Assessment of breast density and related cancer risk, pending

• Automatic method and system for computer aided detection of architectural distortion in mammography, pending

• Enhanced visualization for medical images, pending

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