Medical Training
Resume:
Karen S. Spencer
Costa Mesa, CA. 92627
EDUCATION
B.S., cum laude, California State University at Long Beach
Major areas of study: Microbiology and Chemistry
Saint Joseph Hospital and Medical Center, Orange, CA
Medical Technology Internship
University of Southern California, Los Angeles
Major area of study: Finance
ADDITIONAL TRAINING
Mayo Clinic, Rochester, MN
Advanced training in abnormal hematology
Coulter Corporation, Flow Cytometry Division, Miami, FL
Training on Profile Flow Cytometer
Cedars-Sinai Medical Center, Los Angeles, CA
Advanced training in flow cytometry and image analysis
Becton-Dickinson Corporation, Flow Cytometry Division, San Jose, CA
Training on FACsCalibur Flow Cytometer
Becton-Dickinson Corporation, Flow Cytometry Division, San Jose, CA
Training on FACsCanto II Flow Cytometer
Siemens Healthcare Diagnostics Inc., Chemistry Division, Tarrytown, NY
Training on Advia Chemistry 1800
Meso Scale Diagnostics Inc., Chemistry Division, Tarrytown, NY.
Training on Meso Scale Discovery’s Multi-Array Technology multiplex immunoassay system
Luminex Corporation, Austin, TX.
Training on Luminex Flexmap 3D multiplex immunoassay system
CAREER SUMMARY
Experienced in many areas of the clinical and research laboratories including proficiency in 6-color flow cytometry, and analytical testing on blood, urine and other body fluid. Demonstrated organizational and implementation skills in establishing a flow cytometry department. Independently conducted experiments in a research environment. Have worked in all departments of clinical laboratories, including blood bank, hematology, coagulation, urinalysis, chemistry and immunology. Have demonstrated proficiency in a GLP environment.
PROFESSIONAL EXPERIENCE
Professional
Allergan, Inc., Irvine, 2006 to Present
Employed as part of a of customer-oriented team to provide clinical laboratory testing for human
research programs and drug development efforts. This position required expertise in performing
analytical testing for hematology, coagulation, urinalysis, chemistry and immunology. Also, an
ability to maintain laboratory equipment, organize and manage data within the clinical laboratory,
GLP compliance and efficiency.
Flow Cytometry Specialist
Hoag Memorial Cancer Center, Newport Beach, 2000 to 2006
Promoted from Research Associate to Flow Cytometry Specialist in January 2000. Performed hematology,
urinalysis, chemistry, immunology and microbiology testing. Other duties included those of the research
associate plus assisting the lab coordinator in the daily management of the cell biology laboratory. Also,
worked closely with the Sr. Scientists in developing research procedures and in preparing data for
presentations. In addition was involved in teaching and supporting other flow cytometry technical
personnel.
Research Associate
Hoag Memorial Cancer Center, Newport Beach, 1998 to 2000
Employed in the Cell Biology Laboratory. Performed all hematology, urinalysis, chemistry,
immunology and microbiology testing. Other duties included supervising the flow cytometry
department, maintaining cell and tissue culture in a sterile environment and assisting in the
development and implementation of new methods of immunotherapies for the treatment of cancer.
Medical Technologist
Western Medical Center, Santa Ana, 1986 to 1990 and 1994 to 1998
Employed as a generalist in blood banking, hematology, chemistry, coagulation, and urinalysis
with demonstrated mastery of all areas of the clinical laboratory.
Supervisor Flow Cytometry
Western Medical Center, Santa Ana, 1990 to 1994
Independently developed and wrote all policies and procedures to establish a flow cytometry department. Created reporting formats and protocols. Liaisoned with pathologists to correlate results with expected clinical outcomes. Presented seminars to health care personnel and the community.
Supervisor Hematology Department
Western Medical Center, Santa Ana, 1980
Supervised all personnel on all shifts. Duties included: review of reports for accuracy and
completeness, teaching of medical technology students, training of new employees, scheduling,
writing and maintaining procedure manuals and preparing employee evaluations.
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PUBLICATIONS
IIB-MEL-J ALLOGENEIC TUMOR CELL VACCINE CONTAINS GRP94, AN IMMUNOSTIMULATORY HEAT SHOCK PROTEIN. C Malone, AD MacIntosh,
PM Schiltz, L Beutel, K Spencer, JMC McGee, RO Dillman. Hoag Cancer Center, Newport Beach, CA
TUMOR INFILTRATING LYMPHOCYTES (TIL) GENERATED FROM MELANOMA IN
THE PRESENCE OF AUTOLOGOUS DENDRITIC CELLS (DC) AND AUTOLOGOUS
TUMOR. PM Schiltz, C Malone, AD MacIntosh, KS Spencer, RO Dillman. Hoag Cancer
Center, Newport Beach, CA
CRYOPRESERVED DENDRITIC CELLS (DC) MAINTAIN PHENOTYPE
AND ABILITY TO ELICIT AN ALLOGENEIC RESPONSE POST
RECOVERY. PM Schiltz, C Malone, KS Spencer, RO Dillman. Hoag Cancer Center, Newport Beach,
CA.
SERUM-FREE CRYOPRESERVATION SOLUTION FOR STORAGE OF TUMOR CELL VACCINGE. RS Selvan,
AN Cornforth, KS Spencer, CC Malone, and RO Dillman. Hoag Cancer Center, Newport Beach, CA.
CYTOKINE ANALYSIS OF MELANOMA PATIENTS TREATED WITH AUTOLOGOUS TUMOR
VACCINE. Patric M. Schiltz, KS Spencer, Adam T. Wright, Michael E. Aldridge, Colin C. Malone,
Salvatore M. Cilia, Robert O. Dillman, Hoag Cancer Center, Newport Beach, CA.
ANALYSIS OF LYMPHOKINE ACTIVATED KILLER (LAK) CELLS USED FORADOPTIVE
IMMUNOTHERAPY OF HIGH GRADE GLIOMAS. PM Schiltz, KS Spencer, C Malone, RO Dillman.
Hoag Cancer Center, Newport Beach, CA.
IL-10 AND IL-2 LEVELS IN MELANOMA PATIENTS UNDERGOING IMMUNOTHERAPY WITH
VACCINES DERIVED FROM AUTOLOGOUS TUMOR CELL LINES. RO Dillman, PM Schiltz, KS
Spencer, Lee S. Schwartzberg, NM Barth, C DeLeon, AA O’Connor, SK Nayak. Hoag Cancer Center,
Newport Beach, CA; West Clinic, Memphis, TN.
CHARACTERIZATION OF SURFACE MARKERS ON DENDRITIC CELLS USED TO SUPPORT A
PHASE I/II TRIAL OF ACTIVE SPECIFIC IMMUOTHERAPY FOR METASTATIC RENAL CELL
CARCINOMA PATIENTS. Schiltz, PM, Spencer KS, Novak JD, Beutel LD, Dillman RO.
ACTIVITIES/INTERESTS
Running, Mountain Biking, Guitar, Tennis, Reading and Traveling
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