Technician Assistant

James Suchy Ph.D.

** ****** ***** **.

Wrentham, MA 02093

Tel 508-***-****

***********@*****.***

Academic Appointments:

Post-doctoral Research Associate – Division of Infectious Diseases: Biomedical Sciences

Tufts University – North Grafton, MA 7/09-2/11

Responsibilities: Performing and testing experimental drugs for infectious diseases (Shiga toxin, Cryptosporidium, and ricin) on in vivo and in vitro models

Research Associate - Center for Cellular Neurobiology and Neurodegenerative Research University of Massachusetts - Lowell, MA 9/05 – 6/09

Responsibilities: Performing and designing experiments for neurodegenerative disease (Alzheimer’s disease and ALS models both in vivo and in vitro), helping to maintain lab safety, cleaning, and ordering products and supplies

Teaching Assistant - Biochemistry Techniques

University of Massachusetts - Lowell, MA 9/07 - 5/08

Responsibilities: Setting up labs, assisting and teaching students biochemical techniques such as purifying and quantifying proteins and enzyme activity, spectrophotometry, pH and buffer preparation, grading

Professional Positions:

Research Associate II Contract - Aveo Pharm. -Drug Discovery Cambridge, MA 10/11-present

Responsibilities: Establishing and implementing in vivo tumor xenograft models, efficacy studies, PK/PD

Scientist Contract- Incytu Corp. Lincoln, RI 6/11- 8/11

Responsibilities: Establish IACUC, IACUC Chair, PI, designing performing in-vivo studies for various types of cancer and infectious diseases, writing grants, managing animal facility

Research Associate Contract- Toxikon- Pharmacology Department Bedford,MA 3/11- 5/11

Responsibilities: Dosing, bleeding, necropsies, collecting data on GLP/GMP, PK/PD

Animal Care Technician - ORS- Charles River Labs Contract Facility

University of Massachusetts - Lowell, MA 9/04 - 5/08 Responsibilities: Animal care and health checks, handling, husbandry, breeding

Education:

2009 Ph.D. Biomedical Engineering and Biotechnology

University of Massachusetts – Worcester, Boston, Dartmouth, Lowell

Dissertation: Effects of Nutritional Supplementation on the Progression of Motor Neuron Degeneration in a Murine Model of Amyotrophic Lateral Sclerosis

Research Interests: Neurodegenerative diseases such as Alzheimer’s disease (APOE knock out mice) and Amyotrophic Lateral Sclerosis (NSC-34 cell line/ SOD-1 G93A mice)

2006 M.S. Biology: Biotechnology

University of Massachusetts - Lowell

Thesis: Effect of Nutritional Supplementation on Progression of Motor Neuron Disease

2004 B.S. Biology

University of Massachusetts - Boston, MA

Technical Skills:

Animal experience: various surgical methods, anesthesia/euthanasia techniques, behavioral monitoring, blood collections (facial veins, saphenous vein, retinal periorbital, cardiac), dosing (subcutaneous (SQ), intraperitoneal (IP), intramuscular (IM), intravenous (IV), intradermal (ID), ocular, oral gavage )

Cell culture experience: cell maintaining, fixing, cell viability/counting/cytotoxicity, in vitro assays, micro staining, infection of cells, electrical cell-substrate impedance sensing (ECIS).

Biochemical and Molecular experience: Protein isolation and purification, DNA isolation and purification, gel electrophoresis: Northern, Western, and Southern Blot, ELISA, immunohistochemistry, various biochemical assays, biostatistical analysis aseptic /sterile lab techniques, GLP.

Current Certifications:

Healthcare Provider by American Heart Association

Animal Laboratory Assistant Technician (ALAT)

Laboratory Animal Technician (LAT)

Published Manuscripts:

Suchy J, Chan A, Shea TB. Dietary supplementation with a combination of alpha-lipoic acid, acetyl-l-carnitine, glycerophosphocoline, docosahexionic acid and phosphatidyl serine reduces oxidative damage to murine brain and improves cognitive performance. Nutrition Res 29: 70-74.

Suchy J, Lee S, Ahmed A, Shea TB. Dietary supplementation S-adenosyl methionine delays the onset of motor neuron pathology in a murine model of amyotrophic lateral sclerosis. Neuromolecular Med. Online: Sept 16, 2009.

Suchy J and Shea TB. Dietary supplementation with pecans delays the onset of neuromuscular decline in mice overexpressing G93/A-mutant human SuperOxide Dismutase-1. Nutri Neurosci

Published Abstracts:

Suchy J, Lee S, Ahmed A, Shea TB. Effect of nutritional supplementation on motor neuron disease. Neuroscience Convention, 2008 Washington D.C.

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