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Microbiology, Nano-biotechnology

Location:
Kolkata, West Bengal, India
Posted:
December 01, 2020

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Resume:

EXPERIENCE:

Research:

Teaching:

CURRENT RESEARCH ACTIVITIES:

After joining IISER Kolkata, I got immense exposure to the whole new dimension of the cutting edge technologies and multidimensional research activities. I started working on several different possible corridors of nanobiotechnological research. The most promising are; use of 2D materials that have the capability to slash down the vigorous progress of cancer. Arghya Bandyopadhyay, Ph.D

Microbiology & Nanobiotechnology

OBJECTIVES:

Knowledge is ubiquitous, it does

not have shape. It is our efficiency

how we give it a shape. I am

wandering to collect some of the

scintillating tiny fractions from it by

my zeal to learn and utilize the best

part of experience gained from my

intimacy with microbiology and

nano-biotechnology. It is my aim in

life to make out the best possible,

sustainable development in the field

of biology with the help of modern

cutting edge weapon like

nanotechnology.

TECHNICAL SKILLS:

Nanotechnology:

Preparation, characterization and

application of nanomaterials;

TEM, SEM, AFM, XRD, SQUID

etc.

Molecular Biology:

RAPD, RFLP, ARDRA, PCR,

ELISA

Blotting (Northern, Southern and

Western), cloning etc.

Computational biology:

In-silico analysis of protein

structure, Molecular dynamics

simulation, Docking.

Metagenomic and General:

Isolation of DNA from various

sources for metagenomic studies,

Bacterial and animal cell culture

etc.

Specific technological skill:

DNA sequencer operation (Ion

torrent, Life technologies)

1. Institute: Indian Institute of Science Education and Research (IISER), Kolkata Department: Centre for Advanced Functional Material and Department of Biological Sciences

Designation: National Post Doctoral Fellow

Duration: June 2019 – till date

2. Institute: ICMR-RMRC, Dibrugarh

Section: Enteric Diseases

Designation: Field Investigator

Duration: December 2017- February 2018

3. Institute: Indian Institute of Science Education and Research (IISER), Kolkata Department: Department of Chemical Sciences

Designation: Research Associate

Duration: December 2013 – June 2017

4. Institute: University of Kalyani, India

Department: Microbiology

Designation: University Research Scholar

Duration: August 2008 - November 2013

5. Institute: University of Kalyani

Department: Biochemistry and Biophysics

Designation: Master student

Duration: June 2005 - August 2005

(M.Sc. Thesis: Isolation, Identification and Characterization of Multiple Drug Resistance Bacteria from Hospital Waste.)

1. Institute: Sarada Ma Girls’ College (West Bengal State University) Department: Microbiology

Designation: Assistant Professor (on contract)

Duration: August 2018 – March 2019.

2. Institute: Jagannath Kisore College (Burdwan University) Department: Microbiology

Designation: Lecturer

Duration: August 2006 - August 2008.

RESEARCH INTEREST:

1. Nanobiotechnology for the

development of biochip/biosensors,

and theranostic device

4. Effect of engineered

nanomaterials on human system

3. Metagenomic study of bacterial

community

4. Protein structure and function

Induction of plant stress response genes can be possible by the use of nanomaterial and also plant pathogens can be killed by using nanoparticle of metal and fungicides. Without losing the connection with my Ph.D laboratory, I am also engaged in some different aspect of nanobiotechnological applications, like, combinatorial therapy of cancer with nanoparticle and ionizing radiation. Another notable field is investigation of the effect of heavy metal nanoparticles on human pulmonary system. EDUCATION:

SUMMARY OF RESEARCH:

Predoc:

The study of my Doctoral thesis is based upon the unique properties of nano materials. As the title of my thesis is “Application of superparamagnetic nanoparticles and its nanocomposite for biomolecular recognition” the whole work mainly focused on the SPIONs (superparamagnetic iron oxide nanoparticles) and the noble metal, e.g. gold, modified SPIONs. The work was aimed to synthesis of SPIONs and surface modification of the same with gold with minimum size increment along with negligible loss of magnetic property, hence vigorous characterization of the particle was done by different techniques TEM. SEM. AFM, DLS, SQUID, XRD, FTIR etc. Further exploitation in biological field was done by biomolecular recognition study. The biomolecular recognition property of the synthesized nanomaterial was checked by interaction of nanomaterial with biomolecules. Crucial outcome of the work are; a 12 nm gold coated SPION was synthesized, which have the predetermined chemically activated surface patches (like acupuncture ball) for biomolecule attachment. Hence, the whole nanomaterial is able to detect complementary oligos at the level of pM concentration using the SPR property of the nanomaterial. Another interesting finding is the capability of unmodified SPIONs to extract DNA from a ruptured bacterial cell suspension. Postdoc:

1. Synthesis of silicon based nanosheet, structural study of the self assembly of the synthesized material and application as a potent anticancer agent/drug delivery vehicle. 2. Synthesis of polymeric nanomaterial and application as a drug delivery system. 3. Molecular dynamics simulation of nanobio interface. 4. Synthesis of different anti-fungal nanomaterial for different cropping plant systems. 5. Synthesis and delivery of drug conjugated (for obstructive airway diseases), different nanomaterials and their effect on human pulmonary system.

6. Synergistic effect of metal nanoparticle and ionizing radiation on cancer cell as a possible anticancer treatment.

7. Use of biocompatible metal nanoparticle to curb 4th generation XDR bacterial pathogen. 8. Synthesis and use of different nanomaterial to induce stress response genes in cropping plant system.

9. Treatment of cancer and bacterial pathogens using natural compound of endophytic origin. 2008-2013 2004-2006 2001-2004

Ph.D in Microbiology,

Specialization in

Nanobiotechnology.

University of Kalyani, India

M. Sc in Microbiology.

Vidyasagar University, India.

First class with 62.7%

B. Sc (Honors) in Microbiology

Vidyasagar University, India

First class with 62.625%

National level examination qualification:

1. 2007 GATE qualified in Life Science, organized by IIT-Kanpur. Score: 330, All India Rank: 1599. 2. 2016 ICAR-ASRB NET qualified in Agricultural Microbiology. Score: 66%. PUBLICATIONS:

Intellectual property:

Granted:

1. Synthesis of surface active gold nano layer fabricated iron oxide nano composite. A. Bandyopadhyay, S. Chatterjee, K. Sarkar. Indian Patent no: 290222. 2. A method for gold nanoparticle mediated delivery process of plasmid DNA into non competent E. coli for higher transformation efficiency. S. Chatterjee, A. Bandyopadhyay, K. Sarkar. Indian Patent no: 318003.

Original research articles:

1. Rapid Isolation of genomic DNA from E. coli XL1Blue strain approaching bare magnetic nanoparticles. Current Science, 2011. A. Bandyopadhyay, S. Chatterjee, K. Sarkar. I.F: 0.756 2. Effect of iron oxide and gold nanoparticles on bacterial growth leading towards biological application. Journal of Nanobiotechnology, 2011. S. Chatterjee, A. Bandyopadhyay, K. Sarkar. I.F: 5.816

3. Potential application of superparamagnetic nanoparticles for extraction of bacterial genomic DNA from contaminated food and environmental samples. Journal of the Science of Food and Agriculture, 2013. S. Basu, S. Chatterjee, A. Bandyopadhyay, K. Sarkar. I.F: 2.422 4. A simple one pot purification of bacterial amylase from fermented broth based on affinity towards starch funtionalized magnetic nanoparticle. Preparative Biochemistry and Biotechnology, 2014. T. Paul, S. Chatterjee, A. Bandyopadhyay, D. Chattopadhyay, S. Basu, K. Sarkar. I.F: 1.117 5. Fungal contamination of the respiratory tract and associated respiratory impairment among saw- mill workers in India. ERJ Open Research, 2015. A. Adhikari, S. Sahu, A. Bandyopadhyay, Paul D. Blanc, S. Moitra. I.F: 3.35

6. Enhancement of anticancer activity and drug delivery of chitosan-curcumin nanoparticle via molecular docking and simulation analysis. Carbohydrate Polymers, 2018. P. Yadav, A. Bandyopadhyay, A. Chakraborty, K. Sarkar. I.F: 6.044 7. Exposure to heavy metals alters the surface topology of alveolar macrophages and induces respiratory dysfunction among Indian metal arc-welders. Toxicology and Industrial Health, 2018. S. Moitra, J. Ghosh, J. Firdous, A. Bandyopadhyay, M. Mondal, J. K. Biswas, S. Sahu, S. Bhattacharyya, S. Moitra. I.F: 1.635

8. The destructive spontaneous ingression of tunable silica nanosheets through cancer cell membranes. Chemical Science, 2019. A. Bandyopadhyay, P. Yadav, K. Sarkar, S. Bhattacharyya. I.F: 9.556

9. Enhancing the radiotherapeutic index of gamma radiation on cervical cancer cells by gold nanoparticles. Gold Bulletin, 2019. P. Yadav, A. Bandyopadhyay, A. Chakraborty, Sk. M. Islam, K. Sarkar. I.F: 2.279

10. Individual circadian preference (chronotype) is associated with asthma and allergic symptoms among adolescents. ERJ Open Research, 2020. P. Haldar, A-E. Carsin, S. Debnath, S. G. Maity, I. Annesi-Maesano, J. Garcia-Aymerich, A. Bandyopadhayay, S. Moitra, M. Kogevinas, S. Moitra. I.F: 3.35

Publications in conference proceedings:

1. A rapid isolation of ultrapure bacterial genomic DNA for genomic studies using bare magnetic nanoparticles. Proceedings of National Conference on Biodiversity & Natural Resource Utilization. 2010. A. Bandyopadhyay, K. Sarkar.

2. Bacterial growth response on interaction with iron oxide and gold nanoparticles: Measuring risk to the Environment. IEEE Xplore. DOI: 10.1109/NSTSI.2011.611986. S. Chatterjee, A. Bandyopadhyay, K. Sarkar.

Editorial article/Correspondence/Letter to the editor and other types of article: 1. Therapeutic potential of nanoparticulate system for treatment of protozoan infection. Aperito Journal of Bacteriology, Virology and Parasitology, 2014. P. Yadav, A. Bandyopadhyay. 2. Bio-organic Nanoparticles: Breaking the Barrier in Nanoparticle-mediated Pulmonary Drug delivery. International Journal of Pulmonary & Respiratory Sciences, 2017. A. Bandyopadhyay, S. Moitra.

3. Mica pneumoconiosis: a neglected occupational lung disease. The Lancet Respiratory Medicine. 2018. S. Moitra, A. Bandyopadhyay, S. Moitra.

Articles under communication/preparation status in peer reviewed journals: 1. Bident use of bacteria in arsenic bioremediation and biosynthesis of gold nanoparticle– a plausible cost-effective biomining method.

2. Carbon nanotube upregulated SLT1 gene via miR-820b/miR-2-3p targeting DICER-DUF-Dead Box helicase TF which induced salinity stress tolerance in jute (Corchorusolitorius L). 3. Biocompatible copper nanoparticles (CuNPs): A potential candidate to serve against multidrug resistant bacteria and their biofilms.

Abstract published:

1. A comparative study on cultivable and uncultivable bacteria from gut community of Labeo bata. IMS (Indian Mycological Society) 2009, University of Calcutta, Kolkata, India. 2. Synthesis of stable bare magnetic nanoparticles for rapid isolation of ultrapure bacterial DNA for molecular studies. ICNEA (International Conference on Nanobiomaterials on Environmental Applications) 2009, NEERI, Nagpur, India.

3. A rapid isolation of ultrapure bacterial genomic DNA for genomic studies using bare magnetic nanoparticles. National Conference on Biodiversity & Natural Resource Utilization, Department of Botany, Visva-Bharati, Santiniketan. 2010, West Bengal, India. 4. Bacterial growth response on interaction with iron oxide and gold nanoparticles: Measuring risk to the environment. NSTSI (International Conference on Nano Science, Technology and Societal Implications) 2011, C. V. Raman College of Engineering, Bhubaneswar, India. 5. Synthesis of gold nano layer protected magnetic nanocomposite: A novel approach for developing a biosensor. ICNANO (International Conference on Nanomaterials and Nanotechnology) 2011, University of Delhi, New Delhi, India.

6. Surface functionalized gold nanoparticle mediated transformation of non competent E. coli: A nanobiotechnological breakthrough. ICNANO (International Conference on Nanomaterials and Nanotechnology) 2011, University of Delhi, New Delhi, India. 7. One pot synthesis of zero valent iron nanoparticles for it’s potential application in waste water treatment. 4th international conference on Advance Nano materials, ANM-2012, IIT Chennai. 8. A superparamagnetic nanoparticle based approach towards the purification of biomolecules: Nucleic acid and Protein. 4th international conference on Advance Nano materials, ANM 2012, IIT Chennai.

9. Rapid detection of Coliform bacteria from water samples using magnetic nanoparticles. 53rd annual conference of Association of Microbiologist of India, November, 2012, KIIT, Orissa, India. 10. In vitro evaluation of iron oxide, gold, and their composite nanomaterials against cancer cell line. International Conference on Polymeric Biomaterials, Bioengineering & Biodiagnostics, October, 2014, New Delhi, India.

11. Pulmonary Candidiasis and respiratory impairments among saw-mill workers. 16th Joint National Conference of National College of Chest Physicians (NCCP) & The Indian Chest Society (ICS). November, 2014. Agra. India.

Gene Bank submission:

1. KF483576.1 (http://www.ncbi.nlm.nih.gov/nuccore/KF483576.1). OTHER ACHIEVEMENT(S):

1. Featured in “Who-is-Who” section of DRDO funded compendium on Indian Capability On Nano Science And Technology, released on the eve of the Inauguration of “National Workshop on Nanotechnology for Defense Applications” (NWNDA-2011) at Solid State Physics Laboratory, DRDO, New Delhi, India. (Published by: MacMillan publishers India Ltd., bearing ISBN 978-935- 059-030-0.)

2. Editorial Board Member of Aperito Journal of Bacteriology, Virology and Parasitology (AJBVP). 3. Reviewer of Toxicology and Industrial Health.

CONTACT AND PERSONAL INFORMATION:

I hereby declare that the above information is correct to the best of my knowledge and belief.

Permanent Address:

Arghya Bandyopadhyay

32/B, Shiber Gali, Bhattacherjee

Para

P. O: Halisahar

Dist: 24 Pargana (N)

West Bengal, India

743134

Official Address:

Arghya Bandyopadhyay

National Post Doctoral Fellow

Centre for Advanced Functional

Material and Department of

Biologoical Sciences.

Indian Institute of Science Education

and Research (IISER), Kolkata.

Mohanpur.

Dist: Nadia. West Bengal, India

741246

Date of birth: August 27, 1983

E-mail:

adh9wh@r.postjobfree.com;

Phone: +91-900*******.



Contact this candidate