Sasmit S. Deshmukh, Ph.D.

***-****, ***** ****** adf7t1@r.postjobfree.com

Toronto, ON – M2M3W1 Tel. 514-***-****

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PROFILE

• Over 12 years of multidisciplinary research experience and strong knowledge in biophysics, chemistry, protein chemistry and biochemistry

• Currently pursuing Lean Six Sigma Certification from CSSC

• Proven written and oral communication skills as evidenced by scientific accomplishments, publications and presentations

• Strong experience and knowledge of working in GMP area with pathogens in CL-2

• Demonstrated experience in quality operations – OOS, OOT, Deviations, CAPA, CCR, audit readiness, DI

• Strong knowledge of GMP, GLP and ICH guidelines

• Proven leadership skills in undertaking and carrying out different projects

• Solid analytical skills for data interpretation with attention to details

• Demonstrated logical reasoning, problem solving and troubleshooting skills COMPETENCIES

• Teamwork • Leadership • Management • Communication

• Innovation • Flexibility • Technical proficiency • Quick learner COMPUTER AND TECHNICAL SKILLS

• Computer skills: MS Office suite, LIMS, Publisher, Sigma Plot, Origin, PyMol, QDoc, TrackWise Digital, and Adobe Photoshop

• Instrumental techniques: Biacore SPR, Bio-layer interferometry (BLI), Raman microscopy, FTIR microscopy, Moisture analyzer, Pipetting robot, Ion exchange and column chromatography, Thin-layer chromatography, HPLC, SEC-MALS, ELISA, Western Blot, RT-PCR, SDS-PAGE, GC, Autoclave, Cyclic Voltammetry, AUC, DLS, Zeta Potential-PALS, DSC, ITC, nanoDSF, Dual polarized interferometry (DPI), Laser flash photolysis (LFP), UV/VIS/NIR Optical spectroscopy, Spectroelectrochemistry, CD spectroscopy, Raman spectroscopy, FTIR spectroscopy, Laser diffraction, Langmuir-Blodgettry, and Fluorescence spectroscopy PROFESSIONAL EXPERIENCE

Scientist 2018-Present

SGS Canada Inc., Toronto, Canada

• Directly involved in QC lab work, method development, transfer, qualification and validation activities

• Leading projects pertaining to biosimilars, binding assays of proteins, antibodies and gamma receptors

• Successfully designed, planned and executed different projects pertaining to drug products and drug substances

• Demonstrated experience in technical writing, reviews and approvals of SOP, protocols, reports and worksheets Associate Scientist 2015-18

Sanofi Pasteur Ltd., Toronto, Canada

• Projects: Raw materials, Tuberculosis vaccine candidate, Herpes simplex virus, Inactivated polio virus, New vaccine projects, Adjuvant optimization

• Implemented LEAN methodologies and contributed towards PAT (Process Analytical Technology)

• Developed PALS, SEC-MALS, FTIR, CD, fluorescence and Raman spectroscopy methods for characterization and identification of raw materials, vaccine components, drug products and drug substances

• Designed and qualified FTIR method (GMP) for raw material release

• Method validation and qualification: FTIR, DLS, nanoDSF

• Successfully led 10+ investigational studies including raw materials and thereby contributed to decision making of over $ 100 M batch release saving substantial amount of money

• Developed analytical and biophysical methods for successful characterization of raw materials to final products

• Successfully led team members in project related problems in multiple instances to meet deadlines

• Trained lab members and colleagues on new methods

• Published 5 first author papers in scientific journals Sasmit S. Deshmukh, Ph.D.

adf7t1@r.postjobfree.com Tel. 514-***-****

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PROFESSIONAL EXPERIENCE (CONT’D)

• Presented webinar sponsored by Beckman Coulter Inc.

• Awards: Early career scientist award from Bill and Melinda Gates Foundation (travel award) Postdoctoral Fellow 2013-15

Concordia University, Montreal, Canada

• Developed and optimized standard working parameters for dual polarized interferometer to study membrane protein and their structural changes at the sub-molecular level

• Identified structure-function relationship, protein-protein and protein-lipid interactions of plasminogen and str. Enolase

• Discovered evolutionary related link in the development of oxygenic photosynthesis by studying effects of different transition metal ions on membrane proteins

• Trained other lab members on various scientific backgrounds

• Published 3 papers in scientific journals

Research Assistant 2007-13

Concordia University, Montreal, Canada

• Worked and optimized upstream and downstream bioprocessing steps for bacteria

• Extracted membrane protein from bacterial sources

• Identified membrane protein-lipid interactions at the molecular level

• Thoroughly studied structural changes of membrane proteins for molecular information

• Discovered Nature’s billion-year-old battery key to storing energy: http://phys.org/news/2012-04-nature-billion- year-old-battery-key-energy.html. Also highlighted in the Canadian Chemical News July/August 2012 edition.

• Studied structure-function relationship of proteoliposomes to optimize protein stability in artificial membranes

• Identified and optimized protein structural changes to model it as a biocapacitor for energy storage

• Published 5 first author papers in scientific journals

• Presented seminars and posters in various conferences Teaching Assistant 2007-13

Concordia University, Montreal, Canada

• Taught courses to undergraduate students (up to 25) in the organic chemistry laboratories and supervised laboratory experiments

Chemical Engineering (intern) 2005

Neelikon Food Dyes and Chemicals Ltd., Roha, India

• Analyzed various plant level processes and developed purification techniques of R-Salt and G- Salt EDUCATION

Doctor of Philosophy, Chemistry 2013

Concordia University, Montreal

THESIS: Molecular assignment of light-induced structural changes using site-directed mutant reaction centers.

• GPA: 4.23/4.30 and outstanding thesis and excellent defense award

• Awards: Concordia graduation bonus ($1000), Hydro-Quebec graduate ($5000), Concordia Accelerator ($5000) Master of Science, Chemistry 2009

Concordia University, Montreal

THESIS: Light-induced conformational changes in the photosynthesis reaction center from Rhodobacter sphaeroides. Bachelor of Technology, Chemical Technology 2006

Institute of Chemical Technology, India

PROFESSIONAL TRAINING AND DEVELOPMENT

• Diploma in Leadership and Management 2018

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