Jose Candelario, M.D., Ph.D.
Home Address
P.O. Box 593
French Camp, Ca 95231
Cell: 562-***-****
************@*****.***
Education
Frank H. Netter MD School of Medicine, Quinnipiac University, North Haven, CT
M.D. May 2018
Keck School of Medicine, University of Southern California, Los Angeles, CA
Ph.D. 2010 Molecular Microbiology and Immunology
California State University, Dominguez Hills, Carson, CA
B.S. 2003 General Biology
USMLE Step 1 Score: 225; Step 2: 220; Step 2CS: pass; Step 3: 198
Work Experience
Surgical Resident, 6/2018-7/2020
San Joaquin General Hospital
Assistant Professor, 1/1/13-6/1/13
La Jolla Bioengineering Institute
Postdoctoral Scientist, 2010-2012
La Jolla Bioengineering Institute
Graduate Research Assistant, 2004-2009
Dept. of Molecular Microbiology and Immunology
Undergraduate Research Assistant, 2002-2003
Harbor-UCLA Medical Center Research and Education Institute
Undergraduate Research Assistant, 2001-2002
CSU Dominguez Hills Dept. of Biology
Publications:
1.J. Candelario and M. Chachisvilis, Activity of bradykinin B2 receptor is regulated by long-chain polyunsaturated fatty acids. PLoS One, 8 (2013) e68151. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068151
2.J. Candelario and M. Chachisvilis, Real time detection of G protein activation using monomolecular G FRET sensors, (2013) J Recept Signal Transduct Res 33(1): 63-72. http://informahealthcare.com/doi/pdf/10.3109/10799893.2012.759589
3.J. Candelario, H. Tavakoli and M. Chachisvilis, PTH1 Receptor is Involved in Mediating Cellular Response to Long-Chain Polyunsaturated Fatty Acids, PLoS One, 7 (2012) e52583 http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052583
4.J. Candelario, Y. L. Chen, P. Marjoram, S. Reddy, L. Comai, A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction, Aging, 4(8)(2012) 567-577 http://www.impactaging.com/papers/v gel ele4/n8/full/10083.html
5.J. Candelario and Mirianas Chachisvilis, Mechanical stress stimulates conformational changes in 5-hydroxytryptamine receptor 1B in bone cells, Cell and Molecular Bioengineering, 3 (2012) 277-286 http://rd.springer.com/article/10.1007/s12195-012-0232-0
6.J. Candelario, S. Borrego, S. Reddy, L. Comai, Accumulation of distinct prelamin A variants in human diploid fibroblasts differentially affects cell homeostasis, Exp Cell Res,317(3)(2011)319-29. http://www.sciencedirect.com/science/article/pii/S0014482710004805
7.B. Li, S. Jog, J. Candelario, S. Reddy, L. Comai, Altered nuclear functions in progeroid syndromes: a paradigm for aging research, ScientificWorldJournal, 9 (2009) 1449-62. http://downloads.tswj.com/2009/261056.pdf
8.J. Candelario, S. Sudhakar, S. Navarro, S. Reddy, L. Comai, Perturbation of wild-type lamin A metabolism results in a progeroid phenotype, Aging Cell, 3 (2008) 355-67. http://onlinelibrary.wiley.com/doi/10.1111/j.1474-9726.2008.00393.x/pdf
Invited Lectures and Presentations
1.“Proteasome Inhibitor, Carfilzomib, Inhibits Proliferation and Induces Apoptosis in Triple Negative Breast Cancer Cells, the role of cyclin-D1, p21 and c-Jun.” 2019 Northern California Chapter, American College of Surgeons, Annual Educational Meeting, Berkeley, CA (March 2019)
2.“The SAS combined with ASA-PS classification to predict postoperative morbidity in short-term surgical brigades.” Capstones Scholar day. Quinnipiac University (April 2018).
3.“Normal Pressure Hydrocephalus: A Case Report.”
Inter-professional healthcare Education. Quinnipiac University (May 2017).
4.“Patient satisfaction, spine-care navigation and medical comprehension to improve outcomes of patients with degenerative spine diseases.” Medical Student Annual Research Symposium (MedStARS). Quinnipiac University, North Haven, CT (August 2015).
5.“Development and application of G-protein and GPCR biosensors to study cellular signaling” The Scripps Research Institute, San Diego, CA (February 2013).
6.“ Mechanical stress stimulates conformational changes in serotonin receptor 1B” Center for Behavioral Cardiovascular Heath, Columbia University Medical Center, New York, NY (February 2012).
7.“ Mechanical stress stimulates conformational changes in 5-hydroxytryptamine receptor 1B in bone cells” NHLBI Cardiovascular Diversity Research Supplement Awardee Session, Orlando, FL (November 2011).
8.“PTH1R & 5HT1b receptors are involved in mediating the actions of LCPUFAs” The American Society for Bone and Mineral Research, San Diego, CA (October 2011).
9.“A filtering strategy identifies a forkhead box transcription factor as a downstream effector of lamin A dysfunction” The Progeria Research Foundation Workshop on Progeria, Boston, MA (April 2010).
10.“Hutchinson Gilford Progeria Syndrome and the role of Lamin A in the onset of the progeroid cellular phenotype.” Keck School of Medicine, USC, Los Angeles, CA January 2010.
11.“Mechanism of Staphylococcus Aureus resistance to platelet microbicidal proteins and the role of membrane fluidity” presentation was Runner-up in the California State University Student Research Competition 2003 Biological and Agricultural Sciences category
Honors, Awards
Frank H. Netter MD School of Medicine Grant 2014-2015
Dr. Bruce Koeppen (Founding Dean) Scholarship Award 2014-2015
Federation of American Societies for Experimental Biology (FASEB) travel award 2013
FASEB travel award 2012
Postdoctoral Research Supplement Award, NIH/NHLBI, 8/2010 - 2/2013
National Institute of Aging F31 Award, 2005-2009
Public Health Services Predoctoral Training Grant, 2004
CSU Student Research Competition, 2003
Graduated with Honors, General Biology, 2003
Maximizing Access to Research Careers (Marc) Undergraduate Student Training in Academic Research (U*STAR) Award, 2002
Minority Biomedical Research Support (MBRS)-Research Initiative for Scientific Enhancement (RISE) Award, 2001
Dean’s Honor Roll, 2001-2003
Professional Memberships:
American College of Surgeons
American Association for the Advancement of Science
Sigma Xi, The Scientific Research Society
Professional Service:
Peer reviews scientific articles for PLOS ONE.
Research committee member since 2019
Volunteer:
Science Fridays volunteer to underserved high school students.
Foot Clinic: foot care and service for the underserved/ homeless 2017
Surgery mission trip at Dominican Republic 2017
Skills
-Wound debridements ranging from pressure ulcers to necrotizing fasciitis.
-Wound vac placement and changes including the VERFLO system
-Placement of large wound managers.
-Ostomy care
-Wet to dry dressings
-Graft placement, split thickness skin graft and ACELL grafts.
-Basic life support
-CPR Certification American Red Cross
-Microbiology techniques
-Biochemistry techniques
-Molecular Biology techniques
-Cell Biology techniques
-Bioinformatics techniques
-Computer software literacy
-Biophysics techniques
-Animal models techniques
Hobbies:
Hiking
Guitar
Reading
Teaching