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MANJUSHA VERMA

Senior Research Scientist

Email: adclh2@r.postjobfree.com

Phone: 832-***-****

Globally Educated (Ph. D; Postdoc) & Highly Skilled Chemical Research Scientist with proven Leadership in Research and Development of High Market Value Projects including Conceptualization, Analysis, Formulation, Development.

ACCOMPLISHMENT

• Technology Development Leadership – Technology Development and Management from Lab Scale to Testing- Developed a process for Diluent Reduction using Catalytic Approach and methods.

• Patent published -Viscosity reduction of crude oil through structure determination of asphaltene molecule. US Patent No. 10, 287, 510 B2, 2019

• Baker Hughes, GE Leadership Program (Cultivate), Baker Hughes, 2018-2019

• Recognition Award- Baker Hughes, 2016

• Engineering Development Program EDP2- Baker Hughes 2018

• Subject Matter Expert Organic Chemistry: Derivation and Application of the structure and properties of different Crude Oil and materials involved in technical synthesis of products and analysis.

• Reservoir Engineering – Stanford University, 2017

• Quality Management of the Laboratory – American Chemical Society – 2016

• Chemical Engineering for Chemist- American Chemical Society – 2016 EMPLOYMENT HISTORY

Baker Hughes Houston, TX

Mar ’19-Present: Senior Research Scientist

• Directed research project team and analyzed data on development of the Catalytic process for bitumen.

• Communicated status to executive management including the CEO and customers.

• Developed a groundbreaking Catalytic Process to yield High Quality Crude Oil, that accomplishes low viscosity, and complete elimination of Diluent, Asphaltene Precipitation, Coke, and Olefins, using Batch Reactors, and Fixed Bed Reactors for the extraction and transport of bitumen. Oversaw laboratory testing and planned testing and experiments based on laboratory data to build a field prototype unit

• Developed the fundamental molecular understanding of different crude oils- Canadian crude oil Devon, MEG, Cenovus Heavy oil. Structure of asphaltene and porphyrin of different crude oils has been achieved by experimental methods Developed and Patented. (Patent published -Viscosity reduction of crude oil through structure determination of asphaltene molecule. US Patent No. 10, 287, 510 B2, 2019)

• Design and Development:

o Novel Catalyst for upgrading of the heavy crude oil. o New method for the testing crude oil- Olefins detection in crude oil Page 2 of 7

o Procedure for development of dewatering of crude oil- distillation and clarifying and demulsifying agent (Surfactant). Water and BSW analysis o Analysis Metal and porphyrin content in the crude oil o Different methodologies and instrumentation for analysis of different crude oil. o Synthesis of new products of application from crude oil

• Direct, coordinate, or advise personnel in test procedures for analyzing components or physical properties of matter.

• Coordinate, analyze and monitor quality control and product assurance tests results to ensure products meet or exceed quality and reliability, specifications and standards.

• Interpret test results, compare them to established results and data report and presentation

• Train other team researchers to perform laboratory procedures for instruments and assay Baker Hughes, a GE company Houston, TX

Feb ‘16-Mar ‘19 Lead Engineer/ Research Chemical Engineer (RDD IV)

(Project: Heavy Crude Oil and Asphaltene- Canadian Heavy oil -Peace River oil, Ecuadorian oil) Lab research conducted with following procedures and method for development of the catalytic process for upgrading of different crude oil. The research gave an insight to molecular changes in crude oil due to the catalytic treatment.

• Synthesis of different derivatives of Asphaltene

• Exfoliation Study of Asphaltene

• Separations Methodologies of Asphaltene

• Structure Elucidation of Asphaltene

• Crude Oil- Analysis of components pre-reaction and post reactions of crude oil with catalysts

• Heterogeneous and homogeneous catalyst synthesis for heavy crude oil

• Methodologies/Techniques development for analysis of crude oil, catalysts etc.

• Dewatering crude oil process by distillation and inverted separation method using Surfactant Baker Hughes –Rice University – Joint Collaboration Houston, Texas Jan ‘14-Feb ‘16 Research Scientist/Postdoc

Heavy Crude Oil and Asphaltene.

• Synthesis of different derivatives of Asphaltene

• Exfoliation of Asphaltene

• Separations of Asphaltene

• Structure Elucidation of Asphaltene

• Crude Oil- Analysis of components pre-reaction and post reactions of crude oil with catalysts

• Methodologies/Techniques development for analysis of crude oil, catalysts etc.

• Onset asphaltene precipitation, P value

• Gaseous component analysis

• Carbon Residue, High temperature Simulated Distillation, GCMS, SARA, TAN, KF methodologies etc Graphene

• Synthesis and analysis of single layer of graphene. Page 3 of 7

Georgia Institute of Technology Atlanta, Georgia

Feb ‘06- Oct ‘11 Postdoctoral Research Associate

Postdoctoral Projects: Design, Synthesis, Characterizations, and Fundamental Understanding

• Worked on Projects for DOW, DOE, Conoco Phillips and American Pacific Corporation AMPAC- 1. Synthesis of novel materials for energy conservation and innovative separations 2. Polymer model grafting and mechanism

3. Pharmaceutical/Drug intermediates and novel materials. Synthesis of Ionic Liquids and their structure properties relationship studies ( DOE and Conoco Phillips): Developed a novel class of solvents for post-combustion recovery of CO2 from fossil fuel- fired power plants, which will achieve multiplication of capacity with a concomitant plummet in cost as well it, application role as Surfactant.

Polymer Chemistry (DOW): Developed processes for the facile functionalization of ethylenic polymers model systems using silane and silicone derivatives. Fundamental mechanistic studies are conducted on model compounds representative of ethylenic polymers; graft selectivities (tertiary vs. secondary vs. primary vs. allylic vs. vinylic positions

Drug Discovery (AMPAC): Designed, Synthesized, developed methodology and fundamental study of intermediates for HIV drugs.

• Synthesis of fluorescent Probes for detection of metal ions (copper and zinc) and their study in cells:

Developed a fluorophore-receptor system with porphyrin skeleton, which undergoes emission enhancement upon binding of monovalent copper/zinc under physiological conditions. Our studies in this area have led to some very valuable conclusions, which help in understanding the intracellular storage, trafficking and homeostasis of metal ion in body

• Drug Discovery: Drug design and synthesis of novel topoisomerase inhibitors called dual-acting topoisomerase-HDAC inhibitors for cancer treatment . EDUCATION (Overall first class honor)

• Research Scientist- Rice University (working for joint project Baker Hughes-Rice University) July, 2014-2016.

• Postdoctoral Researcher- Rice University (working for joint project Baker Hughes-Rice University) Jan 2014-July2014.

• Postdoctoral Research Associate- Georgia Institute of Technology 2006-2011

• Ph. D. Chemistry, Indian Institute of Technology, Banaras Hindu University, (IIT-BHU), India

• Master of Science (Organic, Analytical, Physical, Inorganic and Medicinal Chemistry), Banaras Hindu University (India’s No. 1 University), India

• Bachelor of Science (Distinction –Chemistry major), Banaras Hindu University (India’s No. 1 University), India

• Diploma in Computer Applications

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Indian Institute of Technology (IIT BHU) Varanasi, India Ph. D Projects:

• Development of new methodologies for synthesis of bioactive molecules, modification of bioactive molecules and their semi-synthesis (semicarbazone, isatin, benzoxazine, imines etc.). Study of the synthesized compounds as anti-convulsants, anti-viral and anti-tuberculosis agents.

• Methodology Studies: New and facile synthesis of some potentially useful organic products has been achieved by superoxide ion. - selectivity, purity, yield and simplicity of operations involved. RESEARCH EXPERIENCE

Analytical equipments used material studies:

FT-IR, Raman, NMR, GC-MS/GC, X-ray Photoelectron Spectroscopy, XRD, EDS-SEM, TEM, HPLC, DSC, TGA, UV, DLS, Viscometer, Densitometer DMA, Fluorometry, LCMS, HPLC, MALDI MS, ICP, Micro-distillation, Thermometeric Titration, Simulated Distillation, High temperature Sim Dis, Karl Fisher etc

Software:

Matlab, Chemdraw, Mestronova, Peakfit, Topspin, PLC, Chemstation or MassHunter, Microsoft Office etc

LABORATORY, COMPUTATIONAL COMPETENCE & SKILLS

• Handled large quantity of air-unstable, explosive and highly flammable organic reactants and intermediates and carried reactions in inert atmosphere.

• Expertise in various column chromatographic methods like Silica and Alumina Column Chromatography, Chromatotron, HPLC, Gas Chromatography, LC MS and vacuum distillation

(Isolation, purification and structural determination of various kinds of organic compounds).

• Expertise in analyzing and operating spectroscopic techniques like FT-IR, UV, MALDI MS, GC-MS, 2D-NMR (COSY, NOESY, TOCSY, HSQC and HMBC), X-ray Photoelectron Spectrocopy, Raman.

• Expertise in Fluorometry Instrumentation- Quantum Yields, Emission and Excitation Spectra, Dynamic Light Scattering, DSC, TGA, Simulated distillation, Karl Fisher Titration, Thermometeric Titration, Microdistillation

• Design and multistep & total synthesis of various classes of molecules, Experience in high pressure & high temperature reaction (Parr, Thimble, Flow Reactor), Solid Phase peptide synthesis and metal

(Cu, Pd etc) catalyzed reactions.

Synthesis of diversified range of molecules characterized it and analyzed using analytical techniques.

• Ability to purify the molecules in minor amounts (upto 1 mg) and large scale. Able to analyze elemental analysis data

• Developing new methodologies in synthesis-better yield and pure materials as well fundamental studies

• Expertise in various computer programs like windows and chem draw.

• Dealt with hazardous waste.

• Conducted independent research, and worked in a multidisciplinary team-Chemical Engineers, Biochemist, Mentored –Graduate and Undergraduate, Technicians and Postdocs.

• Excellent oral and communication skills. A comprehensive professional reports of investigations; reviews existing patents for the research

• Leadership skills.

AWARDS & FELLOWSHIPS

• Awarded Senior Research Fellowship, University Grants Commission (India’s counterpart of the NSF), India (2004)

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• Awarded B. H. U. Research Fellowship- Junior Research Fellowship (2000) and Senior Research Fellowship, India (2003)

• Qualified ICAR (Indian Council of Agricultural Research) NET (2003)

• Qualified National Eligibility Test (2001and 2002) for research and eligibility for lectureship

(Assistant Professor) in Indian Universities/Institutes.

• Qualified GATE (Graduate Aptitude Test for Engineering), India (2001) TEACHING EXPERIENCE: Lectured chemistry and assistant for practical classes during 2003-04 at undergraduate level at the Indian Institute of Technology, Banaras Hindu University, India Invited Journals Reviewer: Journal of Heterocyclic Chemistry, African Journal of Biochemistry. Journal Reviewer: Current Trends in Biotechnology and Pharmacy, STM (Scientific, Technical and Medical) Journals.

Invited Associate Editor: Bioinfo Publications- Advances in Computational Research. Editor: Research & Reviews: A Journal of Pharmaceutical Sciences. Editorial Board Member: International Journal of Applied Chemistry (IJAC); International Journal of Basic and Applied Medical Chemistry.

Panel Judge: Georgia Tech Research and Innovative Conferences 2011 Member: American Chemical Society

Volunteer- Katy Aquatics Volunteer Swim meets 2018- Present and Baker Hughes- McDonald Children Houston Festival 2018

RESEARCH PUBLICATIONS:

1. Manjusha Verma, Pradeep Venkataraman, Sivaram Pradhan, W. Ed Billups, Scott Wellington, Michael Shammai, Viscosity reduction of crude oil through structure determination of asphaltene molecule. US Patent No. 10, 287, 510 B2, 2019.

2. W. Ed Billups, Manjusha Verma, Bruce Brinson, Elena Vishnyakova, Lawrence Alemany, Michael Shammai, Birch Reduction of Asphaltenes. Synthesis of Hydroasphaltenes, Energy Fuels 2019, 33, 8040-8044.

3. Elena Vishnyakova, Bruce Brinson, Lawrence Alemany, Manjusha Verma, W. Ed Billups, Structural Characteristics and Properties of a New Graphitic Based Material, Chemistry: An European Journal 2016, 1452-1460.

4. Lawrence Alemany, Manjusha Verma, W. Ed Billups, Scott Wellington, Michael Shammai, Solid- and Solution-State Nuclear Magnetic Resonance Analyses of Ecuadorian Asphaltenes: Quantitative Solid-State Aromaticity Determination Supporting the “Island” Structural Model. Aliphatic Structural Information from Solution-State 1H−13C Heteronuclear Single-Quantum Coherence Experiments. Energy Fuels 2015, 29, 6317-6329.

5. Amy Rohan, Jackson Switzer, Kyle Flack, Ryan Hart, Swtha Sivaswamy, Elizabeth Biddinger, Manish Talreja, Manjusha Verma, Sean Faltermeier, Paul Nielson, Pamela Pollet, Paul Schuette, Charles Liotta and Charles Eckert, The Synthesis and the Chemical and Physical Properties of Non-Aqueous Silylamine Solvents for Carbon Dioxide Capture, ChemSusChem, 2012 (Sep 06, 2012, DOI: 10.1002/cssc.201200393).

6. Rani Jha, Emily Nixon, Swetha Sivaswamy, Farhana Momin, Manjusha Verma, Les Gelbaum, Pamela Pollet, Charles L. Liotta, Charles A Eckert, Bharat Chaudhary, Jeffrey Cogen, Radical mediated grafting of polyolefin: A fundamental study, Polymer Materials: Science and Engineering Preprint (243rd American Chemical Society) 2012.

7. Pamela Pollet, Charles L. Liotta, Charles A Eckert, Manjusha Verma, Emily Nixon, Swetha Sivaswamy, Farhana Momin, Les Gelbaum, Bharat Chaudhary, Jeffrey Cogen, Radical mediated graft modification of polyolefins: a fundamental study, Industrial Engineering and Chemical Research, 2011, 50 (21), 122**-*****.

8. Manjusha Verma, Ryan Hart, Kyle Flack, Jackson Switzer, Amy Rohan, Swetha Sivaswamy, Manish Talreja, Elizabeth Biddinger, Pamela Pollet, Charles Liotta and Charles Eckert, Novel class of Page 6 of 7

reversible ionic liquids for CO2 capture, Fuel Chemistry Preprint (242nd ACS National Meeting & Exposition) 2011.

9. Swetha Sivaswamy, Ryan Hart, Kyle Flack, Amy Rohan, JacksonSwitzer, Manjusha Verma, Elizabeth Biddinger, Manish Talreja, Pamela Pollet, Charles Eckert, Charles Liotta, Reversible ionic liquids for carbon dioxide capture: Potential and challenges, Fuel Chemistry Preprint (241st ACS National Meeting & Exposition) 2011.

10. Manjusha Verma, Aneese Chaudhary, Thomas Morgan, Christoph Fahrni, Electronically Tuned 1,3,5-triarylpyrazolines as Cu(I)-selective Fluorescent Probes, Organic and Biomolecular Chemistry, 2010, 8, 363-370, printed as cover art.

11. Aneese Chaudhry, Manjusha Verma, Thomas Morgan, Maged Henary, Nisan Siegel, Joel Hales, Joseph Perry, Christoph J. Fahrni, Kinetically Controlled Photoinduced Electron Transfer Switching in Cu(I)-Responsive Fluorescent Probes, Journal of American Chemical Society, 2010, 132 (2), 737–747 12. Manjusha Verma, Aneese Chaudhary, Christoph Fahrni, Predicting the photoinduced electron transfer thermodynamics in polyfluorinated triarylpyrazolines based on multi linear free energy relationships, Organic and Biomolecular Chemistry, 2009, 7, 1536-1546, printed as cover art. 13. Satish Kumar Singh, Manjusha Verma, Krishna Nand Singh, An efficient use of microwave- superoxide combination for synthesis of organic carbamates and dithiocarbamates, Indian Journal of Chemistry, 47B, 2008, 1545-1548.

14. Manjusha Verma, Krishna Nand Singh, Erik Declercq, Synthesis and antiviral activity of some heterocyclic ureas derivatives, Heterocycles, 68 (1), 2006, 11-22 15. Sundaram Singh, Manjusha Verma, Krishna Nand Singh, Superoxide ion induced oxidation of γ- Lactones to γ-Ketocarboxylic acids in aprotic medium, Synthetic Communication, 34(24), 2004, 4471- 4475

16. Ajay Kumar Shukla, Manjusha Verma, Krishna Nand Singh, Superoxide induced deprotection of 1,3-Dithiolanes: A convenient method of dedithioacetalization, Indian Journal Chemistry, 43B, 2004, 1748-1752

17. Manjusha Verma, Surendra Nath Pandeya, Krishna Nand Singh, James P Stables, Promising anticonvulsant activity of Schiff bases of isatin derivatives, Acta Pharmaceutica, 54, 2004, 49-56 18. Manjusha Verma, Sundaram Singh, Krishna Nand Singh, Synthesis of some new benzoxazine derivatives of biological interest, Heterocyclic Communications, 9(5), 2003, 499-502 Conferences and Abstracts:

1. Manjusha Verma, Bruce Brinson, Lawrence Alemany, Scott Wellington, Michael Shammai, W. Ed Billups, “Birch Reduction of Asphaltene”, 251th ACS National Meeting & Exposition, Energy Fuels,

(2016) San Diego, California, USA.

2. Manjusha Verma, Pradeep Venkataraman, Sivaram Pradhan, Yu-lun Fang, Michael Shammai, Scott Wellington, Ed Billups, Lawrence Alemany, “Distinguishing the Rosary and Island form of asphaltene with solid state nuclear magnetic resonance” 249th ACS National Meeting & Exposition, I&EC (Industrial and Engineering Chemistry), March 22-26 (2015), Denver, CO, USA 3. Manjusha Verma, Krishna Nand Singh, “Novel class of semicarbazones having potent anti-convulsant activity and its comparison with existing drugs” 246th American Chemical Society, September 8-12

(2013), Indianapolis, USA.

4. Manjusha Verma, Krishna Nand Singh, “Novel class of isoindol heterocyclic urea with potent antiviral properties and its comparison to existing drugs” 245th American Chemical Society, March 7-11 (2013), New Orleans, USA.

5. Manjusha Verma, Krishna Nand Singh, “Biological anticonvulsant activities of fluorinated semicarbazones having the moeity isatin or aromatic derivatives” 244th American Chemical Society, August 19-23 (2012), Philadelphia, USA.

6. Rani Jha, Emily Nixon, Swetha Sivaswamy, Farhana Momin, Manjusha Verma, Les Gelbaum, Pamela Pollet, Charles L. Liotta, Charles A Eckert, Bharat Chaudhary, Jeffrey Cogen, “Radical mediated grafting of polyolefin: A fundamental study” 243rd American Chemical Society, March 25-29 (2012), San Diego, CA, USA

7. Manish Talreja, Amy Rohan, Jackson Switzer, Kyle Flack, Swetha Sivaswamy, Maria Gonzalez Miquel, Elizabeth Biddinger, Manjusha Verma, Pamela Pollet, Jose Palomar, Francisco Rodriguez, Charles Liotta, Charles Eckert, “Thermodynamics of Carbon Capture through Reversible Ionic Liquids” AIChE Annual Meeting, October 16-21 (2011), Minneapolis, MN, USA. Page 7 of 7

8. Elizabeth J. Biddinger, Amy Rohan, Jackson Switzer, Swetha Sivaswamy, Kyle Flack, Manish Talreja, Manjusha Verma, Pamela Pollet, Charles Liotta, Charles A. Eckert, “Tunable Reversible Ionic Liquids for CO2 Capture” AIChE Annual Meeting, October 16-21 (2011), Minneapolis, MN, USA. 9. Jackson Switzer, Kyle Flack, Amy Rohan, Swetha Sivaswamy, Elizabeth Biddinger, Manish Talreja, Manjusha Verma, Pamela Pollet, Charles Liotta, Charles Eckert, “Towards Industrially Viable Non- Aqueous Amine Solvent Systems” AIChE Annual Meeting, October 16-21 (2011), Minneapolis, MN, USA.

10. Swetha Sivaswamy, Emily Nixon, Farhana Momin, Rani Jha, Manjusha Verma, Leslie Gelbaum, Pamela Pollet, Charles Liotta, Charles Eckert, Bharat Chaudhary, Jeffrey Cogen, “Fundamental studies on the radical initiated grafting of vinyltrimethoxysilane onto polymeric models” AIChE Annual Meeting, October 16-21 (2011), Minneapolis, MN, USA. 11. Manjusha Verma, Ryan Hart, Kyle Flack, Jackson Switzer, Amy Rohan, Swetha Sivaswamy, Manish Talreja, Elizabeth Biddinger, Pamela Pollet, Charles Liotta, Charles Eckert, “Novel class of reversible ionic liquids for CO2 capture” 242nd ACS National Meeting & Exposition, FUEL, August 28- September 1 (2011), Denver, CO, USA.

12. Swetha Sivaswamy, Ryan Hart, Kyle Flack, Amy Rohan, JacksonSwitzer, Manjusha Verma, Elizabeth Biddinger, Manish Talreja, Pamela Pollet, Charles Eckert, Charles Liotta, “Reversible ionic liquids for carbon dioxide capture: Potential and challenges” 241st ACS National Meeting & Exposition, FUEL-39, March 27-31, (2011), Anaheim, CA, USA. 13. Aneese Chaudhary, Manjusha Verma, Thomas Morgan, Christoph Fahrni, “Rational design of high- contrast Cu(I)-responsive fluorescent probes” 239th ACS National Meeting, March 21-25 (2010), San Francisco, CA, USA.

14. Vishal B Patil, William R Guerrant, Manjusha Verma, Joshua C Canzoneri, Adegboyega K Oyelere,

“Dual acting histone deacetylase-topoisomerase II inhibitors” 236th ACS National Meeting, August 17- 21 (2008), Philadelphia, PA, USA.

15. Krishna Nand Singh, Rajesh Kumar, Manjusha Verma, “An efficient C-C bond cleavage of 1,2-diols using tetraethylammonium superoxide” 233rd ACS National Meeting, March 25-29 (2007), Chicago, IL, USA

14. Manjusha Verma, Krishna Nand Singh, “Exploring the Superoxide Ion : Role in Synthesis of Organic Substrate and Deprotection” 61st Southeastern Regional Meeting of the ACS, October 21-24 (2009), Puerto Rico, USA.

15. Manjusha Verma, Krishna Nand Singh, “Isoindolylureas a new group of antiviral compounds” 232 American Chemical Society, September 10-14 (2006), San Fransico, USA. 16. Manjusha Verma, Krishna Nand Singh, “Fluoro and trifluorosemicarbazones as novel anticonvulsant drugs” 231 American Chemical Society, March 26-30, 2006, Atlanta, Georgia, USA. 17. Manjusha Verma, Surendra Nath Pandey, Krishna Nand Singh, James P Stables, “Synthesis of Schiff bases of Isatins as anticonvulsant”, 6th National Symposium in Chemistry, IIT Kanpur, February 6-8 Feb, 2004, India.

18. Manjusha Verma, National Conference on Global Air Pollution and Water as Sustainer of Life, Sponsored by University Grants Commission of India, New Delhi, India, 9-10 Feb, 2003. Keywords: chemicals research and development asphaltene crude oil production chemicals good laboratory practice pour point 10 years’ experience research excellent presentations skills leadership analytical skills customer relationship commercialization publication and patents olefins pharmaceutical drugs instrumentation catalyst surfactants chemistry ASTM safety regulations HAZMAT data analysis management QC Laboratory Process Control GMP/ISO Fixed Bed Reactor Technical problem solver Organic /Organometallic / Polymer / Petroleum Chemistry / Materials Chemistry/Analytical Chemistry Innovation Design of Experiment DOE

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