Diana Cedeno, Ph.D

**** ** ****** *** #*

El Cerrito, CA 94530

510-***-****

acymqy@r.postjobfree.com

EXPERTISE

• Analytical Chemistry (HPLC Method development and LCMS), Protein-based Assays in a GxP environment and Organic Chemistry (Synthesis).

EXPERIENCE

Principal Scientist. Integrated Analytical Solutions Berkeley, CA. July-Dec, 2016.

• Work in the development, validation and implementation of bioanalytical and biopharmaceutical test methods in a GxP environment (i.e., GLP, GCP and cGMP) at a contract research organization (CRO).

• Execution of biopharmaceutical analyses such as: analysis of dose formulations and mass verification using LC-MS as well as purity using HCP ELISA and SDS-PAGE. Senior Research Chemist. PTRL West (a division of Evans Analytical Group) Hercules, CA. 2014-2016.

• Study Director in charge of long-term studies for pesticide analysis in plants and animals.

• Responsible for writing reports and interacting with the clients as well as training and managing research assistants.

• Used and qualified a diverse range of analytical methods and derivatization reactions for determination of structure of molecules including radiolabeled compounds in a GLP environment.

• Responsible for the proper operation of mass spectrometers in the Metabolism Group. Postdoctoral Research Associate. Lawrence Berkeley National Laboratory Berkeley, CA. 2013-2014.

• Synthesized new photocathodes composed of polymeric materials, light absorbers and catalysts for energy production.

• Tested the stability of interfacial materials under extreme pH conditions and electrochemical potentials. Research Associate. DSM Biomedical Berkeley, CA. 2012-2013.

• Synthesized novel polymers composed of polyurethane and polysiloxane fragments for contact lens applications.

• Formulation development in support of the ophthalmic materials business projects. Postdoctoral Research Associate. The University of Tennessee Knoxville, TN, 2010-2012.

• Synthesized new organometallic cobalt catalyst for the oxidation of lignin (plant polymer) into value-added chemicals.

• Synthesized a novel catalyst composed of a glycal-based bolaform (noncovalently bound nanoscale polymer) attached to a cobalt catalysts that can potentially deconstruct lignin in vivo. Ph.D. research. The University of Arizona Tucson, AZ, 2007-2010.

• Purified after expression in homologous system the cytochrome bc1 enzyme from Rhodobacter sphaeroides as well as a mutant of cytochrome b.

• Synthesized new quinones to be used as substrate analogs for the cytochrome bc1 complex. Determined the midpoint potentials of synthesized quinones, as well as commercially available quinones.

• Using stopped-flow techniques, developed a new method for determining the kinetic rate of reduction of cytochrome c by the cytochrome bc1 complex from Rhodobacter sphaeroides. Page-2

M.S. research. The University of Arizona Tucson, AZ, 2004-2007.

• Synthesized Fe(II) porphyrins (oxygen-sensitive compounds) using glove box and Schlenck line techniques and characterized them using low temperature 2D NMR (NOESY/EXSY). Undergraduate research, Willamette University, Salem, OR, 2004.

• Grew Eichhornia crassipes in a hydroponic solution to determine lead accumulation in the leaves and roots of the plant using voltammetry measurements.

• Synthesized Pb-S chelated compounds (complexes formed by Pb+2 ions bound to cysteine), to study the mechanisms involved in heavy metal accumulation in Eichhornia crassipes. TA, Chemistry I and Organic. The University of Arizona Tucson, AZ, 2004- 2007.

• Taught 2 lab sections of ~25 students in General Chemistry. Graded examinations for General Chemistry I.

• Taught 2 lab sections of ~15 students in Honors Organic Chemistry. Graded examinations for Organic Chemistry I and II.

• Held tutoring sessions once a week in Organic Chemistry. Lab Technician. White Environmental Consultants, Inc. Anchorage, AK, 2002-2004.

• Determined the concentration of lead in paint, soil and air samples using Flame Atomic Absorption Spectroscopy.

• Determined asbestos fiber concentrations in air samples using Polarized Light Microscopy. EDUCATION

• Ph. D., Chemistry, The University of Arizona, Tucson, AZ, 2010.

• M. S., Chemistry, The University of Arizona, Tucson, AZ, 2007.

• B. A., Chemistry, Willamette University, Salem, OR, 2004. SKILLS

Chemistry and Analytical Chemistry

• Analytical methods: LC-MS (Thermo Scientific Orbitrap Q-exactive; Applied Biosystems/Sciex API 4000 tandem quadrupole), HPLC (Agilent, Dionex and Shimadzu), 1D and 2D NMR (Bruker and Varian; HMQC, NOESY/EXSY), EPR, X-ray, IR, GC-MS, UV/Vis, AA, ICP, XPS and GATR-FTIR.

• Bioanalytical methods: ELISA, enzymatic assays and SDS-PAGE.

• Separation/purification methods: Affinity Chromatography for proteins; preparative TLC and HPLC, flash chromatography, recrystallization, extraction and distillation for small molecules.

• Multi-step synthesis of small organic molecules (small and large scale), organometallic complexes and polyurethane polymers.

• Chemical and enzymatic derivatization of compounds.

• Expertise with homogeneous and heterogeneous catalysis.

• Expertise with oxygen-free synthesis and manipulations (glove-box and schlenk line techniques).

• Electrochemical methods: Cyclic Voltammetry, Spectroelectrochemistry in aqueous media and organic solvents, Linear Sweep Voltammetry, Photoelectrochemistry. Page-3

Software

• Laura, Chemstation and Analyst for HPLC; ClassVP and Xcalibur for LCMS; ChemDraw, MestRenova for NMR, SoftMax Pro for Plate reader; Microsoft Word, Excel and Power Point. HONORS AND AWARDS

• The Carl Storm Underrepresented Minority (URM) Fellowship, 2009, GRS.

• Gates Millenium Scholar, funded by the Bill and Melinda Gates Foundation, 2000. PROFESSIONAL AFFILIATIONS

• Member, American Chemical Society, Division of Organic Chemistry, 2008 PUBLICATIONS

• “Hybrid Photocathodes for Solar Fuel Production: Coupling Molecular Fuel-Production Catalysts with Solid- State Light Harvesting and Conversion Technologies.” Cedeno, D.; Krawicz, A.; Moore, G. F., Interface focus, 2015, 5, 20140085.

• “Using Molecular Design to Control the Performance of Hydrogen-Producing Polymer-Brush-Modified Photocathodes.” Cedeno, D.; Krawicz, A.; Doak, P.; Yu, M.; Neaton, J.; Moore, G.; J. Phys Chem. Lett. 2014, 5, 3222-3226.

• “Energetics and Efficiency Analysis of a Cobaloxime-Modified Semiconductor Under Simulated Air Mass 1.5 Illumination.” Krawicz, A.; Cedeno D.; Moore, G. F.; Phys. Chem. Chem. Phys. 2014, 16, 158**-*****.

• “The Effect of Axial Ligand on the Oxidation of Syringyl Alcohol by Cobalt-Salen Adducts.” Elder, T. J., Bozell J. J., Cedeno, D. Phys. Chem. Chem. Phys. 2013, 15, 7328.

• “Catalytic Oxidation of para-Substituted Phenols by a Cobalt-Schiff Base Complex/O2-Selective Conversion of Syringyl and Guaiacyl Lignin Models to Benzoquinones.” Cedeno, D.; Bozell, J. J. Tetrahedron Lett. 2012, 53, 2380.

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REFERENCES

Dr. Thomas Fleischmann, Ph.D.

Director of Metabolism

PTRL West – Evans Analytical Group

625-B Alfred Nobel Drive,

Hercules, CA 94547

Phone: 510-***-****

Email: acymqy@r.postjobfree.com

Dr. Gary F. Moore

Assistant Professor

Department of Chemistry and Biochemistry

Arizona State University

Tempe, AZ 85287-1604

Phone: 480-***-****

Email: acymqy@r.postjobfree.com

Dr. Joseph J. Bozell

Center for Renewable Carbon

The University of Tennessee

2506 Jacob Drive

Knoxville, TN

Phone: 865-***-****

Email: acymqy@r.postjobfree.com

Professor F. Ann Walker

Department of Chemistry & Biology

P. O. Bo 210041

The University of Arizona

Tucson, AZ 85721

Email: acymqy@r.postjobfree.com

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