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Research, Teaching, Physiology, Assistant Professor

Location:
Kolkata, West Bengal, 700001, India
Posted:
October 15, 2016

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Resume:

SUBHABRATA MOITRA

Address for Communication

-Permanent: Segun Bagan, Ghosh Pukur Lane

Krishnagar- 741101, Nadia

West Bengal, India

Tel: +91-347*-******

Mob: +91-743*******

-Email: acw2ft@r.postjobfree.com

Personal Details

-Date of Birth: 9th November 1986

-Nationality: Indian

-Marital Status: Married

Academic Profile

-Doctor of Philosophy (Ph.D.) in Physiology, University of Kalyani, 2015

-Master of Science (M.Sc.) in Physiology, Presidency College, Kolkata, 2009 (First class)

-Bachelor of Science (B.Sc.) in Physiology, Krishnagar Government College (Affiliated to University of Kalyani), Krishnagar, 2007 (First class)

Present Position

-Honorary Scientist, Department of Pneumology, Allergy and Asthma Research Centre, Kolkata, India (2016-)

Past Affiliation

-Postdoctoral Research Scientist at the Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden (2015-2016).

-Employed as Research Fellow in Chest Research Foundation, an affiliate of Cipla Ltd., Pune, Maharashtra, India (2013–2015).

Main Past Research Experience

-Investigation of the variation in the expression pattern of the Sulfatase modifying factor 1 (Sumf1) gene in the monocytes and neutrophils (in blood) in COPD patients and healthy smokers.

-Investigation of the variation in the expression pattern of inducible nitric oxide synthase (iNOS) and Clara cell protein-16 (CC-16) genes in the bronchial brushings of asthmatics.

-Investigation of the prevalence of respiratory morbidity among the tea garden workers of North Bengal due to exposure to tea dust. This study includes clinical, immunological and biomarker characterization with a complete assessment of all possible exposures.

-Evaluation of the effect of occupational cadmium exposure on respiratory morbidity among Indian jewellery manufacturing workers. This included thorough check up of pulmonary function, respiratory symptoms, identification of DNA damage of the lung cells, oxidative stress and structural changes of the red blood cells among Indian jewellery workers.

-Effect of various occupational and environmental exposures on respiratory health of marginal labourers in India.

-Investigation of lung health as obtained from spirometer and body plethysmography and induced sputum in patients with obstructive airway diseases.

-Candida sp. in the respiratory tract among saw-mill workers exposed to wood dust and its relationship with respiratory morbidity.

Current Assignments

-Association between telomere length of bronchial cells and airway remodelling in asthma (Principal Investigator).

-The association between telomere length of peripheral blood mononuclear cells and severity of disease among patients with obstructive airway diseases and idiopathic pulmonary fibrosis (Principal Investigator).

Future Research Interest

Clinical and epidemiological research in occupational and environmental health

-Obstructive airway diseases due to occupational and environmental exposures

-Exposure science (Real time, simulation and complex models)

-Pulmonary effects of urban and indoor air pollution

-Pulmonary health effects of heavy metal-induced toxicity.

Clinical and Molecular Research in Respiratory diseases

-Expression of Sumf1 in occupational exposure-associated emphysema and fibrosis.

-Novel molecules in the treatment of obstructive airway diseases and inflammation in vivo and in vitro.

-Effect of anti-IgE therapeutics on eosinophil inflammasomes.

-Mechanism of neutrophil infiltration in COPD: Role of cytoskeletal proteins

-Mechanism of bronchial cell remodelling in asthma: Role of microtubular proteins.

-Apoptotic cascade mechanism in obstructive airway diseases: Role of mitochondria.

-Expression pattern of circadian genes in respiratory inflammation: Can DOSE follow TIME?

-Membrane biology of the lung epithelial cells in obstructive airway diseases due to different exposures.

-Effect of nanoparticles-mediated antioxidant therapy in the management of OADs: Molecular and clinical aspects.

-In vitro studies (using primary lung cells or secondary cell lines) to investigate the mechanisms of pulmonary toxicity (including oxidant stress, cell injury and production of mediators of inflammation) caused by various agents, such as metallic compounds, therapeutic drugs, pesticides, industrial chemicals and polymers, air pollutants, nanomaterials.

Scholastic Achievements

-Qualified FCE (Cambridge English- Level B2) in Common European Framework of Reference for Languages (CEFR) in 2016.

-1st Position in Master of Science examination in 2009 in Physiology from Presidency College, Kolkata, India

-1st Position in Bachelor of Science examination in 2007 in the Department of Physiology, Krishnagar Government College, Krishnagar, Nadia.

Certificates and Awards

-NAPCON 2014 Award - National Conference of National College of Chest Physicians India (NCCP-I) & the Indian Chest Society (ICS) (NAPCON 2014).

-Silver Sponsorship - European Respiratory Society (ERS), Vienna, Austria (ERS Congress 2012).

-Innovation in Science Pursuit for Inspired Research (INSPIRE) Fellowship for pursuing doctoral research by the Department of Science & Technology, Government of India in 2010.

-Professor Narendra Mohan Basu Memorial Prize and Dr. Chitralekha Mukherjee Memorial Prize by the Presidency College, Kolkata for securing highest marks in the M.Sc. examination in Physiology in 2009.

-Certificate of Merit for securing the highest marks in M.Sc. examination in 2009 by the Presidency College, Kolkata.

-Medal and Certificate of Merit for securing the highest marks in B.Sc. examination in 2007 by the Department of Physiology, Krishnagar Govt. College, Krishnagar, Nadia.

Membership of Societies/Statutory Bodies/Organizations

-Junior Member of the European Academy of Allergy and Clinical Immunology (EAACI), Switzerland

-Life Member of the Society for Environmental Physiology in India (SEPI), India

-Member of the European Respiratory Society (ERS), Switzerland

-Member of the American Thoracic Society (ATS), USA

-Member of the Asian Pacific Society of Respirology (APSR), Japan

Occasional Appointments

-Invited Speaker: 21 Reunión de Invierno Conjunta de las Áreas - Spanish Society of Pneumology and Thoracic Surgery (SEPAR) 2016

-Invited Speaker: Symposium on Occupational lung disease worldwide- European Respiratory Society Annual Congress 2016.

-Organizer: Symposium on Occupational lung disease worldwide- European Respiratory Society Annual Congress 2016.

-Chair of Scientific Session: European Respiratory Society Annual Congress 2016.

-Chair of Scientific Session: European Respiratory Society Annual Congress 2015.

-Reviewer of Congress Abstracts: European Respiratory Society.

-Guest Editor: Current Respiratory Medicine Reviews [Journal].

-Member of the Organizing Committee of the “International Conference on Insights & Management of COPD (ICONIC 2014)”, held at Pune, India on 1st & 2nd February, 2014.

-Past Member, Board of Faculties of the Advanced Pulmonary Function Testing Workshop, organized by Chest Research Foundation, Pune.

-Member of the Organizing Committee of the “UGC Sponsored National Seminar- Current Trends In Human Physiology Research” in Department of Physiology, Presidency College, Kolkata on 18th December, 2008.

Research Grant(s) received:

-Innovation in Science Pursuit for Inspired Research (INSPIRE) grant consisting of personal research fellowship and annual contingency grant from the Ministry of Science & Technology of the Government of India.

Experimental Skills

-Advanced techniques of pulmonary function testing: Diffusion capacity of carbon monoxide in the lungs (DLco), impulse oscillometry (IOS), bodybox plethysmography, sputum induction and processing. Technical knowledge of exhaled breath condensate (EBC).

-Techniques associated with cellular and molecular biology: Primary (peripheral blood mononuclear cells/PBMCs) and secondary cell culture (monocyte-derived macrophages/MDMs), Magnetic beads-associated cell sorting (MACS), fluorimetry, western blotting, PCR, ELISA-based assays, comet and TUNEL assay.

-Microscopy and spectroscopy: Light (bright field and phase contrast), inverted, fluorescence (upright and inverted), spectrophotometry (dual beam). Brief technical and operational knowledge of atomic force microscopy (AFM), confocal microscopy and atomic absorption spectrophotometry (AAS).

-Statistics of Medicine: Basic and some advanced statistical methods (Parametric and nonparametric ANOVA, ANCOVA, linear, logistic and COX regression models, Mediation, Survival and Cluster analysis, etc.). Familiar with statistical software like SPSS, GraphPad Prism and Minitab.

Reviewer of Scientific Journals

International Journal of Chronic Obstructive Pulmonary Disease, E-Biomedicine, Respiratory Research, European Respiratory Journal, ERJ Open Research, Global Health Action, International Journal of Occupational and Environmental Medicine, International Journal of Occupational Safety and Health, Safety and Health at Work, PLoS One

Publications (* corresponding author)

In manuscript

1)Moitra S*, Fireman E, Cullinan P, Jindal SK, Feary J. Occupational lung disease worldwide- updates from the ERS Congress 2016.

Communicated

1)Roy Choudhury S, Datta A, Das PK, Moitra S, Moitra S*. Association between fractional exhaled nitric oxide (FeNO) and serum total IgE levels in asthma. Annals of Allergy, Asthma and Immunology (Submitted)

2)Cullinan P, Munoz X, Suojalehto H, Agius R, Jindal S, Sigsgaard T, Blomberg A, Charpin D, Annesi-Maesano I, Gulati M, Kim Y, Frank AL, Akgun M, Fishwick D, de la Hoz RE, Moitra S*. Prevention and control of occupational lung disease. Lancet Respiratory Medicine (Invited article- Revision submitted).

3)Moitra S*, Bælum J, Murgia N. Respiratory diseases in the marginal labour sectors. Lancet Respiratory Medicine (Invited article- Submitted).

Articles, Book chapters

1)Chatterjee S, Chakraborty K, Moitra S, Bhattacharyya A (2016). Role of proteases in idiopathic pulmonary fibrosis. In: Chakraborty S, et al. (eds). Pathophysiological Aspects of Proteases. (Springer)

2)Pyasi K, Tufvesson E, Moitra S* (2016). Evaluating the role of leukotriene-modifying drugs in asthma management: Are their benefits 'losing in translation'? Pulmonary Pharmacology and Therapeutics; 41: 52-59

3)Moitra S, Thapa P, Das P, Das J, Debnath S, Singh M, Datta A, Sen S, Moitra S* (2016). Respiratory morbidity among Indian tea industry workers. International Journal of Occupational and Environmental Medicine; 7(3): 148-155

4)Kalkana T, Moitra S, Jindal SK, Moitra S* (2016). Increasing burden of COPD in rural India: An example why India warrants primary healthcare reforms. ERJ Open Research; 2: 00032-2016.

5)Kalkana T, Moitra S* (2016). Occupational Exposure: An undermined risk factor of lung diseases in the informal sectors of developing economy. Current Respiratory Medicine Reviews; 12(1): 4.

6)Adhikari A, Sahu S, Bandyopadhyay A, Blanc PD, Moitra S* (2015). Fungal contamination of the respiratory tract and associated respiratory impairment among saw-mill workers in India. ERJ Open Research; 1(2): 00023-2015.

7)Moitra S, Chakraborty K, Bhattacharyya A, Sahu S (2015). Impact of occupational cadmium exposure on spirometry, sputum leukocyte count and comet formation in lung cells among Indian goldsmiths. American Journal of Industrial Medicine; 58(6): 617-624.

8)Moitra S, Bhome A, Brashier BB (2015). Aclidinium bromide/Formoterol fixed-dose combination therapy for COPD: the evidence to date. Drug Design, Development and Therapy; 9: 1989-1999.

9)Moitra S, Maity SG, Haldar P, Pandit AK, Sahu S (2015). Trawler fuel exhaust and respiratory impairments: a cross-sectional pilot study among Indian fishermen working in informal sectors. International Journal of Occupational and Environmental Health; 21(3): 185-191.

10)Moitra S, Puri R, Paul D, Huang YT (2015). Global perspectives of emerging occupational and environmental lung diseases. Current Opinion in Pulmonary Medicine. 21(2): 114-120.

11)Moitra S*, Limaye S, Brashier B (2014). Development of Novel Antioxidants. In: Ganguly NK et al. (Eds) Studies on Respiratory Disorders, Oxidative Stress in Applied Basic Research and Clinical Practice. Springer; New York: pp 349-367.

12)Moitra S*, Blanc PD, Brashier BB (2014). Airflow obstruction among street vendors who refill cigarette lighter with liquefied petroleum gas. The International Journal of Tuberculosis and Lung Disease. 18(9): 1126-1131.

13)Moitra S, Brashier BB, Sahu S (2014). Occupational cadmium exposure-associated oxidative stress and erythrocyte fragility among jewelry workers in India. American Journal of Industrial Medicine. 57(9): 1064-1072.

14)Bandyopadhyay A, Moitra S (2013). Candida sp. AS-SmW-S5 18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence. GenBank. NCBI Reference Sequence: KF_483576.

15)Moitra S, Blanc PD, Sahu S (2013). Adverse respiratory effects associated with cadmium exposure in small-scale jewellery workshops in India. Thorax. 68(6): 565-570.

16)Sahu S, Roy B, Moitra S (2013). Assessment of the lung function status of the goldsmiths working in unorganised sector of India. Lung India. 30(1): 33-37.

17)Sahu S, Maity SG, Moitra S, Sett M, Haldar P (2013). Cardiovascular load during summer work of two age groups of van-rickshaw pullers in West Bengal, India. International Journal of Occupational Safety and Ergonomics. 19(4): 657-665.

18)Sahu S, Moitra S, Maity S, Pandit AK, Roy B (2013). A comparative ergonomics postural assessment of potters and sculptors in the unorganized sector in West Bengal, India. International Journal of Occupational Safety and Ergonomics. 19(3): 455-462

Invited notes, Abstracts, Conference proceedings

1)Moitra S*, Moitra S, Das P, Thapa P, Debnath S, Das J, Chaudhuri S (2015). Exposure associated respiratory impairments among Indian tea industry workers. European Respiratory Journal; 46(suppl 59). OA2915.

2)Rafie S, Moitra S, Brashier B, Salvi S, Naik S, Kulkarni M (2015). Higher plasma cholesterol and low density lipoproteins are associated with increased airway resistance in COPD. European Respiratory Journal; 46(suppl 59). PA523.

3)Moitra S*, Pyasi K, Vincent V, Kodgule R, Salvi S (2015). Association between sputum cytology and lung function in patients with asthma and COPD. European Respiratory Journal; 46(suppl 59). PA2266.

4)Brashier B, Vincent V, Moitra S, Madas S, Salvi S, Bhome A (2015). Impulse oscillometry (IOS) comparisons between asthma and COPD in an Indian population. Respirology; 20:10.

5)Moitra S*, Das V, Madas S, Salvi S. Brashier B (2014). Lung physiological differences of asthma and COPD using impulse oscillometry (IOS). 16th Joint National Conference of National College of Chest Physicians India (NCCP-I) & the Indian Chest Society (ICS) (NAPCON 2014). Agra (India).

6)Moitra S*, Kodgule R, Brashier B (2014). Airway Obstruction and Cardiovascular Diseases: A Model Based Association Study. 16th Joint National Conference of National College of Chest Physicians India (NCCP-I) & the Indian Chest Society (ICS) (NAPCON 2014). Agra (India).

7)Chakraborty K, Moitra S, Bhattacharyya A, Sahu S (2014). Deterioration of lung function is perturbed by sputum neutrophilia and lung cell DNA damage among occupationally cadmium-exposed Indian goldsmiths. European Respiratory Journal; 44(Suppl 58): 1103s.

8)Pyasi K, Brashier B, Londhe J, Das V, Bulsara N, Moitra S, Madas S, Barnes P, Salvi S (2014). Association between quality of life as assessed by St. George's respiratory questionnaire (SGRQ), lung function indices and sputum inflammatory parameters in Indian COPD patients. European Respiratory Journal; 44(Suppl 58): 2189s.

9)Moitra S*, Blanc P (2013). Liquefied petroleum gas associated airflow obstruction in manual cigarette lighter refilling workers. European Respiratory Journal; 42(Suppl 57): 3627s.

10)Moitra S*, Bandyopadhyay A. Pulmonary candidiasis and respiratory impairments among saw-mill workers. European Respiratory Journal; 42(Suppl 57): 406s

11)Moitra S (2013). Exhaled Breath Condensate: an easy tool for non-invasive assessment of pulmonary diseases. RespiMirror (Official Newsletter of Chest Research Foundation); III(IV): 7-8.

12)Moitra S*, Maity SG, Haldar P, Pandit AK, Sahu S (2012). Trawler fuel exhaust and respiratory impairments; a cross sectional study in Indian fishermen. European Respiratory Journal; 40(Suppl 56): 737s.

13)Moitra S*, Sahu S (2012). Respiratory symptoms and lung function tests among the goldsmith engaged in jewellery manufacturing industries in India. European Respiratory Journal; 40(Suppl 56): 183s.

14)Moitra S*, Sahu S (2012). Exposure to workplace acid mists alters the lung functions of the goldsmiths working in unorganized sectors of India. 7th International Conference on Science of Exposure Assessment (X2012). Edinburgh (UK).

15)Moitra S*, Sahu S (2011). Exposure to workplace fumes alters the forced expiratory flow of different intervals and peak expiratory flow rate of the goldsmiths. XXIII Annual National Conference of the Physiological Society of India (Physicon2011). Vijayawada (India).



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