Immunology and metabolism scientist

Yurong Fei, Ph.D., 212-***-****, ***********@*****.***

1

Summary PhD with more than 10 years’ experience in life sciences research. Specialized in immunology, metabolism, cell biology, and endocrinology. Experienced in inflammation, diabetes and metabolic syndrome, bone and cartilage skeletal diseases. Produced 9 first-author, 4 co-author peer-reviewed publications, 7 oral presentations at national/international meetings, and 8 nationally/internationally competitive awards. Do not need visa sponsorship. Bilingual: Chinese, English. Experience Consultant & Scientific Advisor role, Lyfebulb, New York, NY 04/2016 to present Lyfebulb is dedicated to improve the lives of people with diabetes and other chronic diseases.

Assist with book project & events organization.

Review & assess company information for fundraising or investment. Associate Editor, Molecular Medicine 06/2016 to present

Manage the peer-review process: identify and contact the key opinion leaders.

Write and edit for scientific and technical content. Post-doctoral fellow, Immunology, 12/2014 to present The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY Investigate the mechanisms of immune dysfunction, which persists in life threatening infectious disease - sepsis survivors, focusing on myeloid derived suppressor cells as druggable targets.

Drive project, gather, evaluate, and synthesize data.

Presented data at the American Association of Immunologists, Seattle, WA 2016 (poster).

Peer reviewed scientific publications for 4 journals, including Endocrinology.

Spoke at career panels with students, teachers, and parents; Inspire students to become interested in science by volunteering at science/technology fairs. Post-doctoral scientist, Biochemistry & Pharmacology, 05/2012-12/2014 New York University, New York, NY

Studied epigenetic and hormonal regulation: Elucidate the role of protein deacetylase Sirtuin 1, in the actions of parathyroid hormone on bone & cartilage diseases.

Wrote and edited 1 National Institute of Health Director’s Early Independence Award ($2 million for 5 years), selected as one of the 31 finalists from all US candidates, 2013.

Initiated, planned, and conducted 2 projects

Collaborated with key opinion leaders from multiple institutes: New York University, Hospital for Special Surgery, and Harvard Medical School, and GlaxoSmithKline.

Wrote and edited 2 publications with 1 article in writing and 1 article published.

Received 3 honor/awards with $500 - $1500 to present research data at 3 major meetings:

The Federation of American Societies for Experimental Biology meeting on HDACs, Sirtuins, and Reversible Acetylation in Signaling & Disease, Italy, 2013 (speaker &poster).

Sun Valley Workshop on Musculoskeletal Biology, Idaho, 2013 (speaker & poster).

A finalist for NIH Director’s Early Independence Award, Washington DC, 2013 (speaker).

Taught and mentored 4 graduate and college students in research.

Peer reviewed publications for 4 journals, including The Arthritis Research & Therapy. Education PhD, Biomedical Science, University of Connecticut Health Center, CT 08/2007-05/2012

Developed research plans, and performed experiments to investigate the mechanism of bone diseases: first to demonstrate that Wnt signaling plays an important role in the effects of FGF2 in bone formation, which has critical implication in osteoporosis and arthritis.

Managed 3 projects simultaneously: coordinated and scheduled disparate resources.

Wrote and edited 6 first-author publications in peer-reviewed journals,

Obtained 4 awards with $500-$1500 to present data at numerous conferences, including:

The American Society for Bone and Mineral Research, 2009, 2011/12 (poster&speaker).

The Endocrine Society, 2010 (poster).

The Extracellular Matrix in Health & Disease Symposium, Harvard, 2011 (speaker).

Peer reviewed scientific publications for 4 journals, including Journal of Cellular Physiology. Yurong Fei, Ph.D., 212-***-****, ***********@*****.*** 2

MS, Biochemistry and Molecular Biology, 09/2004-07/2007 Chinese Academy of Sciences, Beijing, China

Deciphered the effect of type I diabetes on bone health.

Teaching: prepared lectures, scored homework for graduate level Tumor Cell Biology and Cell Biology, 2005-2006. Mentored 2 graduate students in research.

Initiated and developed research plans, collected and analyzed data

Wrote and edited 2 first-author, and 4 co-authored publications.

Presented data at The International Osteoporosis Conference, 2006 (speaker)

Obtained a scholarship with CNY3000.

Assisted new laboratory setting up.

Courses and Certificate

2016-2019 Navigating Clinical Research, Good Clinical Practice (GCP), Northwell Health, NY 2015 Drug Discovery, Development & Commercialization, Coursera, UC San Diego 2015 Project Mangement: The Basics for Success, Coursera, University of California, Irvine 2014 Essentials of Writing Essays: From Personal to Persuasive, New York University 2014 Confident Communicators of Science, New York University 2013 Lab Management and Communication Skills, New York University Peer-reviewed Publications

1. Yurong Fei, Emi Shimizu, Michael McBurney, Nicola C Partridge. (2015), Sirtuin 1 is a negative regulator of parathyroid hormone stimulation of matrix metalloproteinase 13 expression in osteoblastic cells: role of sirtuin 1 in the action of PTH on osteoblasts. Journal of Biological Chemistry. 2015 Mar 27;290(13):8373-82. PMID: 25631045 2. Fei Y, Gronowicz G, Hurley MM. (2013) Book Chapter - Fibroblast Growth Factor-2, Bone Homeostasis And Fracture Repair. Current Pharmaceutical Design. Executive Guest Editor, Cato T. Laurencin. 19(19):3354-63. Review. PMID: 23432676

3. Fei Y, Hurley MM. (2012) Review - Role of fibroblast growth factor 2 and Wnt signaling in anabolic effects of parathyroid hormone on bone formation. Journal of Cellular Physiology. 227: 3539–3545. Review. PMID: 22378151 4. Fei Y, R-H Xu, Hurley MM. (2012) Review – Stem cell-based bone repair. The American Journal of Stem Cells. 1(2):106-113. Review. PMID: 23671803

5. Fei, Y, Xiao L, Doetschman T, Coffin D, Hurley MM. (2011) Fibroblast growth factor 2 stimulation of osteoblast differentiation and bone formation is mediated by modulation of the Wnt signaling pathway. J Biol Chem. 286(47): 405**-*****. PMID: 21987573

6. Fei Y, Xiao L, Hurley MM. (2011) The impaired bone anabolic effect of PTH in the absence of endogenous FGF2 is partially due to reduced ATF4 expression. Biochem Biophys Res Commun. 19;412(1):160-4. PMID: 21806973 7. Fei Y, Xiao L, Hurley MM. (2010) Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts. Biochem Biophys Res Commun. 391(1): 335-339. PMID: 19913500 8. Yang J, Cao Y, Wang R, Fei Y, Zhang H, Feng P, Liu J. (2010) Anti-resorptive effect of pilose antler blood (cervus nippon temminck) in ovariectomized rats. Indian Journal of Experimental Biology 48 (6), pp. 554-558. PMID: 20882756

9. Yang J, Wang R, Cao Y, Fei Y, Huang Y, He W, and Liu J. (2009) Evaluation of anti-osteoporosis in ovariectomized Wistar rats treated with antler blood by synchrotron radiation X-ray fluorescence microprobe, Spectroscopy, vol. 23, no. 1, pp. 1-9, 2009. doi:10.3233/SPE-2009-0372

10. Zhang X, Fei Y, Zhang M, Wei D, Li M, Ding W, Yang J. (2008) Reversal of osteoporotic changes of mineral composition in femurs of diabetic rats by insulin. Biol Trace Elem Res. 121(3): 233-42. PMID: 179*****-**. Yang J, Fei Y, Cao Y, Wang Y, Huang Y, He W, Liu J. (2007) Comparative element analysis on femur of antler hemo- treated ovariectomized Wistar rats by SRXRF. Nuclear Techniques. 30(5): 407-410 12. Fei Y, Zhang M, Li M, Huang Y, He W, Ding W, Yang J. (2007) Element analysis in femur of diabetic osteoporosis model by SRXRF microprobe, Micron 38(6): 637-642. PMID: 172*****-**. Fei Y, Wei D, Li M, Zhang M, Zhang X, Ding W, Yang J. (2007) Effect of STZ-induced diabetes on bone mineral density and testosterone in rats. Journal of the Graduate School of the Chinese Academy of Sciences, 24(2): 217-222

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