Hesham Ismail

** ******** *****, ***** **** Toronto, ON M4C 5L9

416-***-**** / act84g@r.postjobfree.com

Dear Sir,

I am Research Analyst1 at Centre for Addiction and Mental Health( CAMH) Translational Addiction Research Laboratory (TARL) and Neuroscience's researches. I am Involved in the following studies:

• Exploring Occupancy of the Histamine H3 Receptor by BP1.3656B and BF2.649

(Pitolisant) in Humans Using PET scan

• Impact of Nicotine Metabolism on Brain Dopamine Transmission

• Testing the PPAR Hypothesis of Nicotine Dependence in Humans: Gemfibrozil as a Novel Treatment for Tobacco Addiction

• Exploring Occupancy of the Dopamine D3 Receptor by BP1.4979 in Humans Using PET I have a solid knowledge basis of pharmacology and pharmacokinetics with two year experiences in clinical research besides; the general medical laboratory techniques. Clinical Research diploma, Toronto 2014

Project management O.S.L.T program from Humber College, Toronto 2015 Medical laboratory technician diploma with O.S.M.T certification 2013 I was given the opportunity to gain a significant practice in the research methods, conducting clinical trials, and assisting with the statistical analysis. Also, have the methodical skills to focus on requirements of research data-collection and analysis across a variety of research projects. Over and above; I have the organization skills to co-ordinate data from a wide variety sources especially source documents.

Thankyou so much for your consideration, and I look forward to hearing from you at (416)- 7323806. Please tell me when an appointment may be possible. Yours Truly,

Hesham Ismail

Reviewed – March 24, 2016

Hesham Ismail

1022-11Crescent Place Toronto, ON M4C 5L9

416-***-**** / act84g@r.postjobfree.com

PROFESSIONAL HIGHLIGHTS

Two years experience as Research Assistant and Research Analyst 1 at the Center for Addiction and Mental Health CAMH

Strong knowledge of regulatory requirements concerning clinical trials Extensive knowledge of drug, device development process, human path physiology and diseases. Significant experience in: medical history, vital signs, phlebotomy and E.C.G Clear understanding of clinical trial protocols, regulatory affairs (health- care), I.C.HG.C.P, US F.D.A regulations, R.E.M.S, case report forms, ADE and, informed consent form Knowledgeable in determining study site feasibility, the study protocol, development of study budgets (Cost Estimation), I.R.B requirements, study visits, transcribe source information onto Case Report Forms C.R.F

Bachelor and Master's degree in the field of medicine. WORKING HISTORY

1.Research Analyst at Center for Addiction and Mental Health- Toronto, Ontario November, 2015 – present (part time)

● Maintain research databases which include patient demographics, clinical, Neuropsychological, neuroimaging and genetic variables etc.

● Data collection, creating source documents and other documents required for the successful conduction of a clinical research study

● Assist with scheduling study visits, preparing and accompanying subjects for laboratory, PET scan and MRI visits

● Recruiting and screening the subjects for participation in clinical research studies. Actively conducting the following studies at CAMH: 1. Exploring Occupancy of the Histamine H3 Receptor by BP1.3656B and BF2.649 in Humans Using PET

2. Impact of Nicotine Metabolism on Brain Dopamine Transmission 3. Testing the PPAR Hypothesis of Nicotine Dependence in Humans: Embroilment as a Novel Treatment for Tobacco Addiction

4. Exploring Occupancy of the Dopamine D3 Receptor by BP1.4979 in Humans Using PET Reviewed – March 24, 2016

Hesham Ismail

416-***-****/ act84g@r.postjobfree.com

2.Placement at Lambda Therapeutic Research Toronto, Ontario (2months) 2013

E.C.G, phlebotomy, drug, alcohol screening, centrifugal and general medical Laboratory techniques OTHER EXPERIENCES

Internal medicine specialist -Haemodialysis physician 2008-2012 Handled projects in cost estimation, project management for clinical trial study, class 2 new medical devices application, labeling of medical devices and presentations for epidemiological study. EDUCATION

● Post-graduate diploma of clinical research from Academy of Applied Pharmaceutical Science, Toronto, Ontario 2014

● Project management O.S.L.T from Huber College, Toronto 2015

● Medical laboratory technician diploma (Anderson College),Toronto 2013 CERTIFICATES AND COURSES

● Best G.C.P on PET studies C.A.M.H Toronto 2015

● Health Canada Division 5 - drugs for clinical trials involving human subject 2015

● G.C.P. - Regulated Studies (Drugs, Device, N.H.P)

● Responsible Conduct of Research- Life Science 2015

● Ti Council Policy statement T.C.P.s 2013

● Certificates of Clinical Pharmacology, Clinical Safety Assessment, Medical Devices, Post Marketing compliance for safety monitoring and NIH-plain language training 2104

● Career in clinical research from C.R.A.C 2014

● Ontario Society of Medical Technology certificate O.S.M.T 2013

● First aid/CPR training from Red Cross Canada, T.D.G 2012 Hesham Ismail 416-***-**** / act84g@r.postjobfree.com Reviewed – March 24, 2016

REFERENCES:

Bernard Le Foll, MD PhD MCFP

Laureate of the French Academy of Medicine Medical Head, Addiction Medicine Service and Medical Withdrawal Service, Ambulatory care and Structured Treatments, CAMH. Head, Alcohol Research and Treatment Clinic, Addiction Medicine Services, Ambulatory Care and Structured Treatments, CAMH. Head, Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, CAMH. Professor, Departments of Family and Community Medicine, Pharmacology, Psychiatry and Institute of Medical Sciences; University of Toronto. Center for Addiction and Mental Health

33 Russell Street, Toronto, Canada M5S 2S1.

Tel: 416-***-****, ext. 34772 Fax: 416-***-****

act84g@r.postjobfree.com

Patricia Di Ciano, PhD Project Scientist

Center for Addiction and Mental Health 33 Russell St, Toronto, M5S 2S1 Tel: 416-***-**** x34002

act84g@r.postjobfree.com

Linda Cock, Professor in Anderson College

act84g@r.postjobfree.com

Irene Russell, Professor, O.S.L.T, Project Management at Humber College Toronto, Canada Area Higher Education

act84g@r.postjobfree.com

Reviewed – March 24, 2016

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