MS in chemical engineering, seeking entry-level position

Yating Liu

Address: *** ********* ***., ***. *, Syracuse, NY 13210

Tel: 315-***-****, E-mail:******@***.***, ******.***.****@*****.***

SUMMARY & PROFILE

Proficient with unit operation, bioreactor, data collection & stastical analysis, cell culture, analytical chemistry

Substantial experience with experiment design, modeling, process development, technical report

Highly self-motivated and cooperative individual with strong troubleshooting & problem solving capability

EDUCATION

MS, Chemical Engineering, Syracuse University August 2014

Department of Biomedical and Chemical Engineering, LCS School of Engineering, GPA: 3.6

Certificate of Advanced Study in Sustainable Enterprise, Syracuse University May 2013

W hitman School of Management, LCS School of Engineering, SUNY-ESF, GPA: 3.8

BS, Pharmaceutical Engineering, Tianjin University J uly 2 010

Department of Pharmaceutical Engineering, School of Chemical Engineering, GPA:3.6

SKILLS

USP: Cell Culture, Bioreactor (batch, continuous, pilot), Strain Screening, PCR, Fermentation

DSP: Chromatography (HPLC-ESI-MS, LC-MS, GC-MS, Q-TOF, MULDI-TOF), Electrophoresis (2D-PAGE),

Spectrophotometry (UV-VIS), Seperation & Purification, Unit Operation, Process Flow Diagram

Software: ChemDraw, COMSOL, Matlab, Xcalibur, SigmaPlot, Polymath, AutoCAD, Microsoft Office Suite

Modeling & Programming : Gromacs, C/C++, Molecular Dynamic Simulation, Data Analysis, VMD, Linux

Testing: TA-R2 Rheometer, AFM, TEM, TEM, Polymer Material Science, Fundamental Analytical Chemistry

INDUSTRY INTERNSHIPS

Biopharmaceutical R&D Assistant (Co-op)

Jun. – Dec. 2009

CSPC Hebei Zhongrun Pharmaceutical Co., China

Designed expeirmental methods for system biochemical analysis of industrial Pennicillin fermentation.

Separated protein, metabolite and phospholipid constituents from in vitro and in vivo samples. Performend

quantitative and qualitative analyses of biotherapeutic product .

Established micromolecule metabolite, protein and phospholipid profiles of Pennicillin fermentation process from

pilot scale & commercial scale bioreactors. Identified biomarker and proposed critical metabolism mechanism s.

Optimized the purification process. Helped to process technology transfer and implment scale-up protocal.

Process Engineer Intern

May – June 2009

Shandong Jincheng Pharmaceutical & Chemicals Co., China

Conducted thorough investigation of cephams bulk drug pharmaceutical production facility-wide. Enhanced

practical knowledge of raw material selection. Assessed process safety with cGMP regulations.

Compiled process data, performed stastical analysis and summarized in final technical report .

Supported senior engineers to identified opportunities for process performance improvement .

Product Development/ Manufacturing Support Intern

June – Aug. 2008

Jilin Pharmaceutical Co. Ltd, China

E xamined plant operations and evaluated production e fficiency.

A ssist ed p rocess engineer g roup w ith d esigning and modifying manufacturing process s uch as heat

e xchanger and compressor a iming at yield increase a nd productivity i mprovement o f Antifebrin and S ulfa

G uanidine production line.

Coordinated with technical, operation, business and quality team in cross -functional projects.

CONSULTING & COURSE PROJECTS

Jan. 2013 – May 2013

Byrne Dairy. Sustainability - Driven Enterpreneuship Capstone Project

Analyzed market trends and drivers, sSWOT . Defined the scope and objective for the project from technical,

operational and managemental perspective. Assessed plant operation and identified opportunities to maximize

plants energy effciency, reduce waste stream, increase production efficiency and better quantify social benefit .

Sep. 2011 – Dec. 2011

Green Engineering

Reviewed the two different industry manufaturing process for styrene and conducted Life Cycle Analysis on both

methods. Analyzed the techniques, synthesis pathways toxicity, environmental indices, process flow diagram (PFD)

and unit operation in depth. Conducted energy consumption evaluation and cost accounting.

RESEARCH EXPERIENCE

Dr. R. Sureshkumar’s Lab, Syracuse University May. 2011 – Jul 2014

Viscoelastic and Interfacial Mechanisms of Cell-Matix Interactions under Dynamic Environments

Developed self-assembled, viscoelastic F127 solution and studied physical properties of the hydrogel matrix.

Investigated the interation between Pluronic and polystyrene beads / fixed cells. Analyzed the interfacial

phenomenon and programmed the biomechanical response of F127 hydrogel as physical stimlus for cell growth

Developed Pluroic model using C++ code, scripts and large scalecomputing on AIX Linux. Validated models

using hypothesis tests and optimized simulation system using algorithms such as steepest descent.

Performed coarse-grained molecular dynamic simulation of SF-EPS-cell interactions adapting Martini force field.

Calculated potential mean force associated with translocation between cell membrane, extracellular substate

and signal factors.

National Laboratory of System Biochemistry Engineering, Dr. YJ Yuan, Tianjin University

Jan. 2010 – Jul. 2010

Optimized Chlorella Vulgaris Lipid Yield as Source for Biodiesel Production

Estabilshed metabonomic profile of Chlorella Vulgaris using GC-MS.

Identified the key biomarker in the the aggregation of metabolic product process .

Improved the lipid content through genetic modification and environmental optimization of breeding process .

Oct. 2008 – Dec. 2009

Industrialization of Ethanol Production from Cellulose Hydrolysate

Used Pichia Stipitis and Pachysolen Tannophilus as parent strains to create breeding selection pool of various

forward mutant strains. Screened out targeted strains and adapted genome shuffling method for genetic

modification.

Optimized fermentation process and improved ethanol yield .

Enhanced strain tolerance of possible inhibitors generated from ammonia explosion cellullose hydrolysis process.

Quality Control of Multiple Constituents in Traditional Chinese Medicine Compound Formula during the

May. 2009 – Apr. 2010

Preparation Process

Established experiment method for qualitative and quantitative determination of multiple constituents in Fufang

Shanzha formula by HPLC-MS fingerprint methodology. Studied the complex components during the extraction /

purification process; and in oral liquid/ dropping pills/ coated product.

Feb. 2008 – Jul. 2008

iGEM (International Genetically Engineered Machine Competition)

LEADERSHIP & OTHER ACTIVITIES

Aug. 2012 – June 2014

Senator of Syracuse University Graduate Student Organization

Feb. 2012 – Sep. 2013

VP of Net Impact Syracuse-ESF Chapter

Aug. 2010 – May. 2012

Teaching Assistant for CEN 333 Fluid Transport, CEN 341 Heat and Mass Transfer

Beijing Olympics volunteer A ug. 2 008

LANGUAGES

Chinese (Mandarin), English, Japanese

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