Mengru Chang
** ***** ** ****, ****** City, NJ***02
+1-860-***-**** ******.*****@*****.***
EDUCATION
University of Connecticut(UCONN) 09/2017-present
Master of biostatistics GPA:3.2/4.0 Connecticut, USA
China Pharmaceutical University (CPU) 09/2012-06/2016
Bachelor of Science in Pharmacy (GPA:3.2/4.0 Nanjing, China
PROFESSIONAL EXPERIENCES
Beyondspring Pharma., ;Statistics Analysis Dept.; Clinical Data intern 02/2019-Now New York, US
Provided assistance in data reduction and do the quality control of phase three
Query of ECRF, do data collection with SAS
Provide programming of STDM, analysis file specifications, and tables, figures, and listings
R&G PharmaStudies Co., Ltd;Statistics Analysis Dept.; Clinical Data intern 05/2018-09/2018 Beijing, China
Provided assistance in data reduction of HSK3486 and do the quality control of the result in phase Clinical Pharmacokinetic with SAS and R
Study Nonmem, and do some easy work
Peking University Health Science Center;Biostatistics Analysis Dept.; Clinical Data Researcher 09/2016-12/2016
Provided assistance in data reduction, experimental design and result analysis in phase Clinical Pharmacokinetic
Attended graduate classes of Peking University as an observer: Statistical Design &Analysis, Principle & Methodology in Clinical Trial
Nanjing Medical University; School of Public Health Data Entry Intern; 20hrs/week 09/2015-12/2015
A project regarding new drugs’ clinical trial and statistical analysis led by Prof. Hao Yu Nanjing, China
Participated in the research of Shuanghuabaihe that is a traditional Chinese drug
Assisted the project with clinical data processing and data entry by virtue of Epidata and SAS
Otsuka Beijing Research Institute (OBRI); Clinical Development Dept.; Intern; 40hrs. /week 07/2015-08/2015
A research-based enterprise wholly owned by Otsuka Pharmaceutical Co., Ltd. of Japan Beijing, China
Partook in safety data discussion of Tolvaptan’ s effects on heart failure, serious adverse event data reconciliation
Discussed the statistical analysis report regarding Tolvaptan’s effects on Hyponatremia
Ningxia People’s Hospital; Intern; 40hrs/week Summer Vacation, 2013-2014
Took record of patients’ adverse effects, medication time, frequency and dosage of some commonly used drugs
Employed the knowledge of toxicology and pharmacokinetics in clinical practice
RESEARCH EXPERIENCES
A Preliminary Study of EGFR; Graduation thesis advised by Prof. Ling HE 12/2015-06/2016
An assay to investigate the small-molecule inhibitors of Epithelial Growth Factor Receptor Nanjing, China
Modified the parent nucleus of widely-used EGFR-TKIs and screened out 5 alternative drugs
Analyzed activity of the 5 alternative drugs by applying MTT method in IC50 measurement
Selected the optimal alternative drug possessing lower drug resistance and toxicity
Pharmacological Teaching & Research Section, CPU; Lab Assistant; 16 hrs/week 09/2014-12/2014
An assay to explore pharmaceutic effects on the sodium channels openness of cardimyocytes Nanjing, China
Supported the seniors in killing mouse and cell isolation
Independently studied the operations of patch clamp
Understood the design of biological experiments by partaking in data logging and analysis, results interpretation
LEADERSHIP ACTIVITIES
Student Union, School of Pharmacy, CPU; Minister of Video Production Dept 09/2012-06/2014
Organized and coordinated the production of promotional videos and microfilms
Provided technical supports for shoot, editing, scenario, and film directing
SKILLS & HOBBIES
Computer Skills Master of Microsoft Office; National Computer Rank Examination (NCRE) Certificate II
Statistical Skills Proficient in Epidata, SAS, R, Nonmem, SQL, Matlab, Python
Laboratory Skills Proficient in the basics of animal pharmacological experiments and the operations of classical experiments; Skilled in UV-VIS, HPLC, FLUORO, western blot, Cell Culture, Patch clam