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Ph.D. Candidate (Organic Synthesis and Analytical Chemistry)

Location:
Baltimore, Maryland, 21239, United States
Posted:
October 23, 2018

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Resume:

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TIJESUNIMI ODEBODE, M.S.

Morgan State University,

School of Computer, Mathematical and Natural Sciences Department of Chemistry

**** **** **** ****** ****, Baltimore, MD 21251 USA Phone: 301-***-****

E-mail: ac7g4k@r.postjobfree.com

EDUCATION:

2016 till date Morgan State University, Baltimore, MD, USA Ph.D. in Bioenvironmental Sciences (Chemistry),

Advisor: Dr. Santosh Mandal

Dissertation: “Synthesis, photophysical properties, DNA binding studies and anticancer properties of organorhenium sulfonato complexes,” currently enrolled, GPA: 3.746/4.000. 2012 - 2015 Morgan State University, Baltimore, MD, USA M.S. in Science (Chemistry),

Advisor: Dr. Angela Winstead (Primary), Dr. Yousef Hijji (Secondary), Dr. Mathumathi Rajavel (Secondary) Thesis: “Microwave-assisted synthesis and antibacterial activity of phenylacetic acid derivatives on bacterial pathogens,” December 2015, GPA: 3.755/4.000

2006 - 2009 Howard University, Washington, D.C. USA B.S. in Chemistry, Minor in Mathematics,

May 2009, GPA: 3.920/4.000

TEACHING ASSISTANT EXPERIENCE:

Morgan State University, Department of Chemistry

1. Spring 2018: CHEM 204, Organic Chemistry II - Lecture 2. Fall 2017: CHEM 101L, General Chemistry I - Laboratory 3. Spring 2016: CHEM 203L, Organic Chemistry I - Laboratory 4. Fall 2015: CHEM 105L: Principles of General Chemistry I - Laboratory 5. Spring 2015: CHEM 408: Advanced Organic Chemistry - Lecture 6. Fall 2014: CHEM 101L, General Chemistry I - Laboratory 7. Spring 2014: CHEM 101L, General Chemistry I - Laboratory 8. Fall 2013: CHEM 110L, General Chemistry for Engineers – Laboratory RESEARCH EXPERIENCE:

2016 till date Morgan State University, Baltimore, MD, USA Ph.D. in Bioenvironmental Sciences (Chemistry),

Advisor: Dr. Santosh Mandal

• Synthesized organorhenium sulfonato compounds

• Characterized sulfonato compounds by IR, 1H NMR, 13C NMR and X-ray crystallography

• Carry out DNA binding studies using UV-vis, cyclic voltammetry, emission spectroscopy, gel electrophoresis and viscosity methods

• Carry out cytotoxicity studies of these compounds on lymphoma and breast cancer cells

• Determine photophysical properties (absorbance maximum, emission maximum, quantum yield, fluorescence lifetime etc.) of organorhenium sulfonato complexes 2012 – 2015 Morgan State University, Baltimore, MD, USA M.S. in Science (Chemistry),

Advisor: Dr. Angela Winstead (Primary), Dr. Yousef Hijji (Secondary), Dr. Mathumathi Rajavel (Secondary)

• Synthesized phenylacetic acid derivatives through microwave-assisted methods

• Used GC/MS, infrared spectroscopy, and NMR techniques for characterization of compounds synthesized.

• Evaluated the antimicrobial activity of the phenylacetic acid derivatives. 2

2010 – 2012 University of Maryland Baltimore County, Catonsville, MD, USA Graduate Research Assistant

Advisor: Dr. Ian Thorpe

• Used molecular dynamics to determine the mechanism of allosteric inhibition induced in the RNA polymerase from hepatitis C virus when it is bound to multiple allosteric ligands.

• Employed temperature-accelerated molecular dynamics (TAMD) to enhance the rate at which the RNA polymerase enzyme samples distinct conformational states. This work involved the use of electronic structure calculations (Gaussian) as well as molecular dynamics simulations (CHARMM, NAMD). 2009 – 2010 Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD, USA Laboratory Technician,

Principal Investigator: Dr. Katherine Seley-Radtke

• Designed and synthesized modified versions of nucleosides as well as the DNA helix for chemotherapeutic applications

• Purified compounds using column chromatography

• Characterized compounds by 1H NMR

2008 Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA Research Assistant,

Principal Investigator: Dr. Caren Freel Meyers

• Designed and synthesized butyl amine linkers for incorporation into novel dual action pro-drug systems

• Purified compounds using column chromatography

• Characterized compounds by 1H NMR

• Coordinated journal clubs and conducted scientific presentations 2008 Department of Chemistry, Howard University, Washington, DC Research Assistant,

Principal Investigator: Dr. Oladapo Bakare

• Synthesized anti-cancer compounds using 1, 4-napthoquinone parent structures

• Purified compounds using column chromatography

• Characterized compounds by IR and 1H NMR

AWARDS AND SCHOLARSHIPS:

Fall 2017: Advancing Science Conference Grant for oral presentation at the 2017 NOBCCHE National Conference National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCCHE)

Fall 2017: Travel Award for poster presentation at the 2017 American Chemical Society (ACS) National Meeting Chemistry Department, Morgan State University

Summer 2017: Travel Award for oral presentation at the 2017 ACS MARM Conference ACS, Maryland Chapter

Spring 2017: Travel Award for oral presentation at the NOBCCHE Northeast and Midwest Regional Conference Chemistry Department, Morgan State University

Fall 2016: Advancing Science Conference Grant for oral presentation at the 2016 NOBCCHE National Conference National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCCHE)

Fall 2014: Advancing Science Conference Grant for oral presentation at the 2014 NOBCCHE National Conference National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCCHE)

Spring 2014: Travel Award for poster presentation at the 2014 American Society of Microbiologists Meeting School of Computer, Mathematical, and Natural Sciences, Morgan State University Spring 2009: High Honors Award for GPA of 3.5 and up Chemistry Department, Howard University

Spring 2009: $6600 monetary scholarship award to Outstanding Junior Chemistry Major Lubrizol Corporation

Spring 2009: The Dr. John V. Golding cash award to Outstanding Junior Chemistry Major Dr. Golding, Jr., an alumnus of Howard University

Fall 2008: Departmental Scholarship to Chemistry Major with outstanding scholarship and leadership Chemistry Department, Howard University

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Fall 2007: Full-tuition Trustee scholarship for 4.0 GPA for 2006-2007 academic year Howard University

Fall 2007: Merit Award for outstanding scholarship (Cash award made to only 50 students nationwide) National Society of Collegiate Scholars, USA.

Spring 2007: The Lillian Green Childers Award for best GPA in sophomore year Chemistry Department, Howard University

CONFERENCES/WORKSHOPS:

Oral presentations:

1. NOBCCHE 44th Annual Meeting, October 30-November 3, 2017 Synthesis, DNA binding study and anticancer activity of organorhenium sulfonato complexes on hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. 2. ACS MARM Conference, June 4-6, 2017

Synthesis, DNA binding study and anticancer activity of organorhenium sulfonato compounds on hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. 3. Northeast and Midwest Regional Conference, March 16-18, 2017 Synthesis, DNA binding study and anticancer activity of organorhenium sulfonato compounds on hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. 4. NOBCCHE 43rd Annual Meeting, November 8-11, 2016 Microwave Synthesis and Analysis of Heptamethine Cyanine Dyes 5. NOBCCHE 41st Annual Meeting, September 22-28, 2014 Synthesis and antibacterial activity of phenylacetic acid derivatives on bacterial pathogens Poster presentations:

1. ACS 254th National Meeting, August 20-24, 2017

Synthesis, DNA binding study and anticancer activity of organorhenium sulfonato compounds on hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. 2. Eighth Annual Cancer Biology Research Retreat, University of Maryland, Baltimore, June 13, 2017 Synthesis, DNA binding study and anticancer activity of organorhenium sulfonato compounds on hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. 3. 114th General Meeting of the American Society of Microbiologists, May 17-20, 2014 Determination of antimicrobial activity of phenylacetic acid derivatives on bacterial pathogens Workshops attended:

1. Mobile Summer Institute on Scientific Teaching (MoSI), August 14-18, 2017 Training given by the National Academies Summer Institute (NASI) on active learning teaching strategies. PUBLICATIONS:

1. Wilder, P. T.; Weber, D. J.; Winstead, A.; Parnell, S.; Hinton, T. V.; Stevenson, M.; Giri, D.; Azemati, S.; Olczak, P.; Powell, B. V.; Odebode, T.; Tadesse, S.; Zhang, Y.; Pramanik, S. K.; Wachira, J. M.; Ghimire, S.; McCarthy, P.; Barfield, A.; Banerjee, H. N.; Chen, C.; Golen, J. A.; Rheingold, A. L.; Krause, J. A.; Ho, D. M.; Zavalij, P. Y.; Shaw, R.; Mandal, S. K., Unprecedented anticancer activities of organorhenium sulfonato and carboxylato complexes against hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. Molecular and cellular biochemistry 2017.

PROFESSIONAL SOCIETY MEMBERSHIPS:

1. American Chemical Society

2. National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCCHE) PROFESSIONAL SERVICE/LEADERSHIP ACTIVITIES:

1. 2009 – 2014: Maryland State Representative, Bethel Campus Fellowship 2. 2015: Search committee for the Chair of Chemistry Department, Morgan State University 3. 2015 till date: National Core Group Leader, Bethel Campus Fellowship 4. 2016 till date: Organic chemistry laboratory redesign, Chemistry Department, Morgan State University 5. 2017 till date: President, NOBCCHE, Morgan State University Chapter 6. 2017 till date: Safety committee member, Chemistry Department, Morgan State University 7. 2018 till date: President, Science Graduate Student Association (SGSA), Morgan State University REFERENCES: Available upon request



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