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Lei

TanBiology PhD looking for research positions

Lei Tan

*** ****** ***., *** ***, Albany, CA 94706 - Cell: 607-***-**** - ********@*****.***

EDUCATION

Rockefeller University, New York, NY / Cornell University, Ithaca, NY 2006-2012

Ph.D, Chemical Biology Fellow ($180K award), GPA: 4.2/4.3

Peking University, Beijing, China 2002-2006

B.S. Chemistry. GPA: 3.85/4.00, ranked 7th out of 180, Chun-Tsung Scholarship ($5K, 1 out of 180)

TECHNICAL SKILLS

Five-year experience with mammalian cell culture, aseptic techniques, developing high-expressing recombinant cell lines

Five-year experience with molecular biology including cloning, DNA extraction, PCR Amplification, RT-PCR, transfection, RNAi, immuno-blot and immuno-fluorescence.

Four-year experience with live cell imaging and digital image processing with Matlab

Familiar with antibody purification, recombinant protein expression in bacteria and in insect cells, large scale protein expression and purification.

Four-year experience in preparing well-documented protocols and technical reports.

PUBLICATIONS

Tan L, Kapoor TM. Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division. PNAS 2011 108(40):166**-*****.

Tseng BS, Tan L, Kapoor TM, Funabiki H. Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell. 2010 18(6):903-12.

Li C, Qi Y, Teng X, Yang Z, Wei P, Zhang C, Tan L, et al. Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase. J Biol Chem. 2010 285(36):28134-40.

Chen H, Wei P, Huang C, Tan L, Liu Y, Lai L. Only one protomer is active in the dimer of SARS 3C-like proteinase. J. Biol Chem. 2006 281(20):13894-8.

Wei P, Fan K, Chen H, Ma L, Huang C, Tan L, et al. The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase. Biochem Biophys Res Commun. 2006 339(3):865-72.

ACADEMIC EXPERIENCE

Graduate Research Fellow, Rockefeller University, New York, NY 2007-2012

Laboratory of Chemistry and Cell Biology (Mentor: Prof. Tarun M. Kapoor)

Created an automatic data analysis protocol that reduced analysis time by 60%

Published 2 peer-reviewed research papers (cited 12 times in a year) and co-authored 2 grant applications that resulted in $800K funding from National Institutes of Health

Mentored 5 PhD students, managed their projects, monitored progresses and provided feedback

Manage the lab mammalian cell tissue culture equipment usage

Undergraduate Research Fellow, Peking University, Beijing, China 2003-2006

State Key Laboratory for Structural Chemistry of Unstable and Stable Species (Mentor: Prof. Luhua Lai)

Designed an assay for screening anti-viral drugs, reduced the cost of screening by 80%

Co-authored 3 peer-reviewed research papers that have been cited 48 times

Managed summer research project for an undergraduate student from Taiwan

PERSONAL

Languages: English (fluent), Mandarin (native), Shanghainese (native)

Volunteer: Participated in training program for disabled runners in Achilles Track Club; Facilitated socialization for psychiatric patients in the inpatient facility at NY Presbyterian Hospital

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