Medical Project
Resume:
CURRICULUM VITAE
James Tilford Elder, M.D., Ph.D.
Kirk D. Wuepper Professor of Molecular Genetic Dermatology
University of Michigan Department of Dermatology
and Comprehensive Cancer Center
7412 Medical Sciences I
1301 East Catherine
Ann Arbor, MI 48109-5675
Phone: 734-***-****
Fax: 734-***-****
E-mail: ******@*****.***
EDUCATION
9/1966-6/1970 Southwest High School, Kansas City, Missouri
9/1970-6/1974 Northwestern University, Evanston, Illinois; B.S.
(Biomedical Engineering with highest distinction)
9/1974-6/1981 Yale University School of Medicine, New Haven,
Connecticut; M.D. (Medical Scientist Training Program)
9/1974-6/1982 The Graduate School of Yale University; Ph.D. (Molecular
Biophysics and Biochemistry)
POSTDOCTORAL TRAINING
6/1981-6/1982 Postdoctoral Fellow, Department of Chemistry, University
of California at Berkeley
7/1982-6/1983 Intern in Internal Medicine, University of Washington
School of Medicine at Seattle
7/1983-7/1986 Senior Fellow in Dermatology, University of Washington
at Seattle
8/1986-6/1988 Senior Research Fellow in Dermatology, University of
Michigan
ACADEMIC APPOINTMENTS
1988-1994 Assistant Professor, Department of Dermatology, University of
Michigan
1988- Physician, Department of Dermatology, Veterans Administration,
Ann Arbor, MI, and Toledo, OH
1992-1994 Assistant Professor, Department of Radiation Oncology, Division
of Cancer Biology, University of Michigan
1994-2002 Associate Professor, Department of Dermatology, University of
Michigan
1994-2002 Associate Professor, Department of Radiation Oncology, Division
of Cancer Biology, University of Michigan
2002-2008 Professor, Department of Radiation Oncology, Division of Cancer
Biology, University of Michigan
1994 Member, Graduate Program in Cellular & Molecular Biology,
University of Michigan
1994- Member, Center for Molecular Medicine and Genetics, University
of Michigan
2002- Professor, Department of Dermatology, University of Michigan
James T. Elder, M.D., Ph.D. 4/14/11 1
2008 Kirk D. Wuepper Professor of Molecular Genetic Dermatology,
University of Michigan
CONSULTING POSITIONS
1993-1998 Oklahoma Center for the Advancement of Science and Technology
Oklahoma Health Research Program (continuation grant review)
1999-2002 Medical Advisory Board, National Psoriasis Foundation
2006- Committee on Scientific Programs, Society for Investigative
Dermatology,
2008- Scientific Advisory Committee, Lupus Family Registry and
Repository
2009- Scientific Advisory Committee, National Psoriasis Foundation
SCIENTIFIC ACTIVITIES
Editorial Boards
1987 Laboratory Investigation, Reviewer
1989- Journal of Investigative Dermatology, Reviewer
1989- Journal of Cellular Physiology, Reviewer
1990- Archives of Dermatology, Reviewer
1991- Experimental Dermatology, Advisory Board until 2007
1992- American Journal of Pathology, Reviewer
1992- Molecular and Cellular Biology, Reviewer
1992- British Journal of Cancer, Reviewer
1992- Journal of Clinical Investigation, Reviewer
1993- British Journal of Dermatology, Reviewer
1993- Cancer, Reviewer
1994- Skin Pharmacology, Reviewer
1994- Archives of Dermatological Research, Reviewer
1994- Proceedings of the National Academy of Sciences, Reviewer
1994- Genomics, Reviewer
1994- Cancer Research, Reviewer
1995- Blood, Reviewer
1996- Journal of Dermatologic Science, Reviewer
1997- American Journal of Human Genetics, Reviewer
1998- Differentiation, Reviewer
1998- Clinical Cancer Research, Reviewer
1999- Clinical and Experimental Dermatology, Editorial Board
2000- Biochimica Biophysica Acta, Reviewer
2000- Neoplasia, Reviewer
2000- Science, Reviewer
2001- Dermatology, Reviewer
2001- FASEB Journal, Reviewer
2001- Nature Medicine, Reviewer
2001- Cancer Biomarkers, Epidemiology, and Prevention, Reviewer
2002- International Journal of Dermatology, Reviewer
2002- Journal of Rheumatology, Reviewer
2002- Journal of Investigative Dermatology, Associate Editor
2002- Endocrine Reviews, Reviewer
2002- Physiological Genomics, Reviewer
2003- Archives of Dermatological Research, U.S. Editor
2003- Journal of Clinical Immunology, Reviewer
2003- Journal of Cell Science, Reviewer
2003- Human Molecular Genetics, Reviewer
2003- Journal of Medical Genetics, Reviewer
James T. Elder, M.D., Ph.D. 4/14/11 2
2005- Human Genetics, Reviewer
2005- Molecular Pharmacology, Reviewer
2005 Nature Genetics, Reviewer
2006 Nature, Reviewer
2006 Clinical and Experimental Dermatology, Reviewer
2006 Journal of the American Academy of Dermatology, Reviewer
2006 Genes and Immunity, Reviewer
2007 PLOS Biology, Reviewer
2009 Trends in Immunology, Reviewer
2009 American Journal of Physiology, Reviewer
2010 Science Translational Medicine, Reviewer
Study Sections
1992 National Institute of Arthritis and Musculoskeletal and Skin
Diseases, Skin Disease Research Centers
1993-95 Oklahoma Center for the Advancement of Science and Technology
Oklahoma Health Research Program Peer Review Panel
1994- General Clinical Research Center, University of Michigan,
Reviewer.
1995 National Institutes of Health, General Medicine A-2 Study Section.
1995-98 Dermatology Foundation, Medical and Scientific Committee
1996 National Institute of Health Division of Research Grants, Scientific
Review & Information Systems, ZRG4 (OBM-1)
1995-2001 Society for Investigative Dermatology, Committee on Scientific
Programs, Reviewer
1998 National Institutes of Health Division of Research Grants,
Scientific Review & Information Systems, ZRG1-OBM-1 (02),
Clinical Sciences Special Review Panel.
1999 Wellcome Trust, Biological Collections Committee, reviewer.
1999 National Institutes of Health Division of Research Grants,
Scientific Review & Information Systems, ZRG1-OBM-1 (01),
Clinical Sciences Special Emphasis Panel.
1999 National Institutes of Health Center for Scientific Review,
Scientific Review & Information Systems, ZRG-GMA-1 (3B)
Small Business Innovation Research Special Emphasis Panel
2000 National Institutes of Health Center for Scientific Review,
Scientific Review & Information Systems, ZRG-GMA-1 (01)
Small Business Innovation Research Special Emphasis Panel
2000 National Institute of Arthritis and Musculoskeletal and Skin
Diseases Special Emphasis Panel 2001/01 Council ZAR1 AAA-A
(J3), Skin Disease Research Centers
2001 National Institutes of Health Center for Scientific Review,
Scientific Review & Information Systems, 2001/05 Council ZRG-
GMA-1
2001 National Institutes of Health Center for Scientific Review,
Scientific Review & Information Systems 2001/05 Council ZRG1
GMA-1 (10) Small Business Innovation Research Special
Emphasis Panel
2001 Wellcome Trust, London, UK, Reviewer
2001 Michigan Diabetes Research and Training Center, Reviewer
2001 National Institute of Health Center for Scientific Review,
Scientific Review & Information Systems 2002/01 Council ZRG1
GMA-101 (10B) Small Business Innovation Research Special
Emphasis Panel
James T. Elder, M.D., Ph.D. 4/14/11 3
2002 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Loan Repayment Program Evaluation Panel, Reviewer
2002 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel ZAR1 TAS-D O3 1, Individual
Postdoctoral Fellowships in Epidemiology / Clinical Research /
Outcomes Research in Skin Diseases
2003 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel ZRG1-OBM-2-03
2003 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel 2003/10 Council ZRG1-ALY-01-1
2004 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel 2004/6 Council ZRG1-ACTS 01Q
2004 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel ZRG1-MOSS-C 12
2004 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel 2004/10 Council ZRG1-ACTS 01Q
2004 National Institutes of Health Center for Scientific Review, Special
Emphasis Panel ZRG1-MOSS-D 12
2004 VA Merit Review, Immunology B Study Section, Spring 2004
2004 VA Merit Review, Immunology B Study Section, Fall 2004
2005- Society for Investigative Dermatology, Committee on Scientific
Programs, Reviewer
2005 Texas A&M University, Center for Environmental and Rural
Health Pilot Project Program, ad hoc reviewer
2005 National Psoriasis Foundation Fellowship Selection Committee,
Reviewer
2006 VA Merit Review Immunology A Study Section, Fall 2006
2007 Michigan Institute for Clinical and Health Research Pilot and
Collaborative Grant Program, University of Michigan, Reviewer
2007 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel ZAR1 MLB-G 01 1, Centers of Research
Translation, May 23-24, 2007
2008 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel ZAR1 MLB-G M1 1, Building Inter-
disciplinary Research Team (BIRT) Revision Awards (R01), June
24-25, 2008
2008 Veterans Administration Career Development (CADE) Study
Section, August 6, 2008, reviewer
2009 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel, ARRA RC1 Challenge Grants, June 5,
2009, primary reviewer
2010 National Institute of Allergy, Immunology, and Infectious Diseases
ZAI1 PA-I (C1), Atopic Dermatits Research Network, February 2,
2010, reviewer
2010 National Institute of Allergy, Immunology, and Infectious Diseases
ZAI1 PA-I (C2), Atopic Dermatits Research Network: Statistical
and Clinical Coordinating Center, February 2, 2010, reviewer
2010 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel, ZAR1 MLB (M1)1, Centers of Research
Translation, November 17-18, 2010, reviewer
2011 National Institute of Arthritis, Musculoskeletal and Skin Diseases
Special Emphasis Panel, ZAR1 HL (M1)1, Skin Diseases Research
Center Grant Review, March 3, 2011, reviewer
James T. Elder, M.D., Ph.D. 4/14/11 4
2011 Centers for Scientific Review, National Institutes of Health,
Cardiovascular and Autoimmune Disease Genetics Study Section,
2011/05 ZRG1 GGG-C (04) M, March 9, 2011, reviewer
GRANT SUPPORT
Recent
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R29-AR40016), TGF- and Tyrosine Kinase Activation
in Psoriasis ; 50% percent effort; role on project: Principal Investigator;
07/01/89-06/30/94 (approximately $70,000 direct costs annually).
Dermatology Foundation Research Grant, Positional Cloning of Epidermal
Differentiation Genes ; role on project: Principal Investigator; 1/1/93-
12/31/93 (approximately $10,000 direct costs annually)
National Institutes of Health, National Center for Human Genome, Research
Genomic Technology/Genetic Disease Pilot/Feasibility Study (P30-
HG00209-03), Directed Linkage Analyses of Familial Psoriasis ; 20%
effort; Francis Collins, PI; role on project: Investigator; 08/01/93-7/31/94
(approximately $20,000 direct costs annually)
Dermatology Foundation Research Grant, Role of Keratinocyte EGF Receptor
Activation in Human Skin Angiogenesis ; role on project: Principal
Investigator / Mentor; 07/01/95-06/30/96 (approximately $10,000 direct
costs)
National Institutes of Health Training Grant (T32AM07197-16), Training Grant
in Cell and Molecular Dermatology ; John Voorhees, PI; role on project:
Preceptor; 07/01/92-06/30/97 (approximately $90,648 direct costs
annually)
Department of Veterans Affairs Merit Review, Expression and Function of
CaN19 in Malignant Progression ; 25 percent effort; role on project:
Principal Investigator; 10/1/94 - 9/30/97 (approximately $92,500 direct
costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742-04), Linkage Analysis of Familial
Psoriasis ; 20 percent effort; role on project: Principal Investigator; 3/1/94
- 2/28/98 (approximately $198,200 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742-04S1), Linkage Analysis of Familial
Psoriasis (Supplement); role on project: Principal Investigator; 03/01/97-
02/28/98 ($87,760 direct costs)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42248-05), Positional Cloning of Epidermal
Differentiation Genes ; 25% effort; role on project: Principal Investigator;
12/01/93-7/31/99 (approximately $544,560 total direct costs)
Dermatology Foundation, EGF Receptor Regulation of Apoptosis in Wound
Healing ; role on project: Principal Investigator / Mentor; 07/01/97 -
06/30/98; ($25,000 direct costs)
Dermatology Foundation, Mapping Locus Control Regions in the Epidermal
Differentiation Complex ; role on project: Principal Investigator / Mentor;
07/01/97 - 06/30/98 ($10,000 direct costs)
University of Michigan Medical School, Clinical Research Partnership Fund,
JNK/TGF- Signaling in Cutaneous Wound Healing ; 5% effort; role on
project: Principal Investigator; 2/1/99 1/31/01 ($50,000 direct costs
annually)
James T. Elder, M.D., Ph.D. 4/14/11 5
National Psoriasis Foundation, Psoriasis Linkage Consortium; role on project:
Investigator; 9/1/98 8/31/00 ($40,000 direct costs)
National Psoriasis Foundation, Molecular Genetics of Familial Psoriasis; role on
project: Principal Investigator; 9/1/00 8/31/01, ($150,000 direct costs)
VA Merit Review (VA #321), CaN19 Function in Regenerative Epidermal
Differentiation ; 25% effort; role on project: Principal Investigator;
4/01/98 09/30/01 ($98,500 direct costs annually)
National Institutes of Health Training Grant (T32-AR017979-25), Training
Grant in Cell and Molecular Dermatology ; John Voorhees, PI; role on
project: Preceptor; 05/01/97 04/30/02 ($112,248 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742); 20% effort; role on project: Principal
Investigator; Linkage Analysis of Familial Psoriasis ; 3/1/98 2/28/03
($272,171 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742 S2), Linkage Analysis of Familial
Psoriasis (Supplement) ; role on project: Principal Investigator; 3/1/98 -
2/28/03 ($175,000 total direct costs)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R21 AR48405-01), Organ Culture of Basal Cell
Carcinoma ; 10% effort; role on project: Principal Investigator; 9/28/01
7/31/03 ($ 50,000 direct costs annually)
National Cancer Institute, National Institutes of Health (P50-CA69568), SPORE
in Prostate Cancer, Kenneth Pienta, PI; role on project, Pilot Project PI,
2/1/03 7/31/03 ($25,000 total direct costs)
VA Merit Review, S100A2 in Oxidative Stress and Carcinogenesis ; 25% effort;
role on project: Principal Investigator; 4/1/02 3/31/05 ($135,000 direct
costs annually)
Dermatology Foundation Research Fellowship, Novel Xenograft Model of
Psoriasis ; 0% effort; role on project: Principal Investigator / Mentor;
07/01/05-06/30/06 ($30,000 direct costs)
American Skin Association, Novel Xenotransplantation Models in Psoriasis ;
0% effort, role on project: Principal Investigator / Mentor; 1/1/06-12/31/06
($15,000 direct costs)
Foundation for the National Institutes of Health; Genetic Association Information
(GAIN) Network, Collaborative Association Study of Psoriasis :
Goncalo Abecasis, PI: Role on project, Co-Investigator; 7/1/06-6/30-07
(approximately $2,000,000 in genotyping services provided and $65,000
in direct costs)
National Institutes of Health Training Grant (T32-AR017979-30), Training
Grant in Cell and Molecular Dermatology ; 5% effort; role on project:
Principal Investigator; 05/01/02 04/30/08 ($148,507 direct costs
annually).
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742); Linkage Analysis of Familial Psoriasis ;
15% effort; role on project: Principal Investigator; 4/1/04 9/30/09
($350,000 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR050511); Identification of Psoriatic Arthritis
Genes in the MHC, James T. Elder, PI; 5% effort; role on project:
Principal Investigator; 4/1/04 9/30/09 ($175,000 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR054966-02S1); Combined Analysis of Gene
James T. Elder, M.D., Ph.D. 4/14/11 6
Expression and Genetic Variation in Psoriasis (Supplement) ; 0% effort;
role on project: Principal Investigator; 9/1/08 8/31/09 ($50,000 direct
costs)
Dermatology Foundation Research Grant, Biological effects of genetic variation
in the IL 12B and IL23R ; 0% effort; role on project: Mentor. (Johann
Gudjonsson, Principal Investigator); 07/01/08-06/30/09 ($20,000 direct
costs)
National Psoriasis Foundation Research Grant, Phenotype and function of IL-17-
secreting T-cells in psoriasis ; 0% effort, role on project: Mentor. (Allen
Bruce, Principal Investigator); 07/01/08-06/30/09 ($50,000 direct costs
annually)
Current
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR054966); Combined Analysis of Gene Expression
and Genetic Variation in Psoriasis ; 20% effort; role on project: Principal
Investigator; 4/1/07 6/30/12 ($410,320 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR42742); Linkage Analysis of Familial Psoriasis ;
10% effort; role on project: Principal Investigator; 9/28/09 8/31/14
($440,554 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR050511); Identification of Psoriatic Arthritis
Genes, James T. Elder, PI; 10% effort; role on project: Principal
Investigator; 9/28/09 7/31/14 ($406,952 direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (RC1AR058315); Genotyping the NPF Biobank for
Psoriasis Susceptibility Genes, James T. Elder, PI; 5% effort, role on
project: Principal Investigator, 9/30/09-8/31/11. ($322,558 direct costs
annually).
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (R01-AR052889); Amphiregulin in Psoriatic Epidermal
Hyperplasia ; 10% effort; role on project: Principal Investigator; 9/15/06
8/31/11 ($186,529 direct costs annually).
National Human Genome Research Institute (U01 HG005924), Design
Approaches for Sequencing Disease-Associated Regions in Psoriasis ; 5%
effort, role on project: Principal Investigator. 10/1/10-9/31/11 ($160,000
in direct costs)
National Institutes of Health Training Grant (T32-AR017979-33), Training
Grant in Cell and Molecular Dermatology ; 5% effort; role on project:
Principal Investigator; 05/01/08 04/30/13 ($168,438 direct costs
annually)
National Institute of Child Health and Development Developmental Biology,
Genetics and Teratology Branch (T32-HD07505), Training Program in
Organogenesis; Deborah Gumucio, PI; role on project: Mentor; 5/01/07
4/30/12 ($308,000 direct costs annually)
National Institutes of General Medical Sciences, National Institutes of Health
(T32-GM07315-31), Graduate Program in Cellular and Molecular
Biology; Jessica Schwartz, PI; role on project: Mentor; 7/1/75 6/30/12
($577,808 direct costs annually)
Dermatology Foundation Physician Scientist Career Development Grant,
Phenotype and function of IL-17-secreting T-cells in psoriasis ; 0%
James T. Elder, M.D., Ph.D. 4/14/11 7
effort, role on project: Mentor. (Allen Bruce, Principal Investigator);
07/01/08-06/30/11 ($55,000 direct costs annually)
Pending
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (1 R01 AR061495-01); Novel Functions of Amphiregulin
in Keratinocyte Growth and Differentiation ; 5% effort; role on project:
Co-Investigator (Stefan Stoll, Principal Investigator); ($250,000 requested
direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (1R01AR062206-01); Functional Genomics of TRAF3IP2
in Psoriasis ; 5% effort; role on project: Principal Investigator; ($250,000
requested direct costs annually)
National Institutes of Health, National Institute for Arthritis, Musculoskeletal and
Skin Diseases (1 R01 AR062382-01); Longitudinal Pharmacogenetic
Analysis of Psoriasis ; 5% effort; role on project: Co-Investigator (Rajan
Nair and Gerald Krueger, Principal Investigators; ($250,000 requested
direct costs annually)
CERTIFICATION AND LICENSURE
1983 Washington Medical Licensure, #252-**-******* (inactive)
1986 Michigan Medical Licensure, #407650
1988 American Board of Dermatology
MILITARY SERVICE
None
HONORS AND AWARDS
1981 Medical Scientist Training Program Award for Outstanding Academic
Achievement
1987 Stelwagon Prize for outstanding resident research, American Academy of
Dermatology
1991 Howard Fox Visiting Professor, New York University Medical Center,
New York, NY
1993 Visiting Professor, 10th Annual Course for Consultants & Registrars,
Brighton, U.K.
1993 Visiting Professor, University of Kiel, Germany.
1995 Visiting Professor, University of Amsterdam, the Netherlands
1995 Visiting Professor, University of Nijmegen, the Netherlands
1998 Louis Forman Visiting Professor, St. John s Institute of Dermatology,
London, UK
1998 Visiting Professor, University of Leicester, UK
1999 Visiting Professor, Case Western Reserve University, Cleveland, OH
2000 Visiting Professor, University of Gothenburg, Sweden
2001 Visiting Professor, University of Cape Town, South Africa
2001 American Dermatological Association
2003- Best Doctors in America
2004 Visiting Professor, Ottawa Dermatologic Society, Ottawa, Canada
2005 Visiting Professor, Canadian Dermatological Association, Quebec
2005 Visiting Professor, Shanghai Dermatological Society, China
2005 Visiting Professor, Chinese Society for Investigative Dermatology, China
James T. Elder, M.D., Ph.D. 4/14/11 8
2006 American Skin Association Award for Outstanding Achievement in
Psoriasis
2007 Visiting Professor, Department of Dermatology, University of Cincinnati,
Cincinnati, OH
2007 Visiting Professor, Department of Dermatology, University of
Pennsylvania, Philadelphia, PA
2008 Kirk D. Wuepper Professor of Medical Genetic Dermatology, University
of Michigan
2008 Visiting Professor, Department of Cellular and Developmental Biology,
Oregon Health Science University, Portland, OR
2009 Eugene Farber Lecturer, Society for Investigative Dermatology, Montreal,
Canada
2010 Fine Lecturer in Dermatology, Emory University, Atlanta, GA
2010 Clinical & Health Services Research Award, University of Michigan
2011 League of Research Excellence, University of Michigan
MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES
American Dermatological Association
American Academy of Dermatology
Society for Investigative Dermatology
2006-present Committee on Scientific Programs
2010 Co-Chairman, Committee on Scientific Programs
American Society for Human Genetics
National Psoriasis Foundation,
1999-2002 Medical Advisory Board
2009- Scientific Advisory Committee
Dermatology Foundation
Michigan Dermatological Society
TEACHING ACTIVITIES
National and International
1988-92 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Focus
Session, American Academy of Dermatology
1988 Lecture, Chromatin Structure and Gene Expression in Deletion-
type Hereditary Persistence of Fetal Hemoglobin (HPFH) Insti-
tute of Human Genetics Seminar, University of Minnesota,
Minneapolis
1990 Lecture, Regulation of Epidermal Growth and Gene Expression
by Transforming Growth Factors and Retinoic Acid, INSERM-
U.184/CWRS-LGME, Strasbourg, France.
1990 Lecture, Autocrine and Paracrine Regulation of Keratinocyte
Growth, Cutaneous Biology Research Center, Department of
Dermatology, Harvard Medical School, Massachusetts General
Hospital, Boston
1990 Lecture, Autocrine and Paracrine Regulation of Keratinocyte
Growth, Department of Dermatology Grand Rounds, University
of California at San Francisco
1991 Howard Fox Lecture, Autocrine and Paracrine Regulation of
Keratinocyte Growth, New York University Medical Center, New
York
James T. Elder, M.D., Ph.D. 4/14/11 9
1991 Lecture, Expression of Retinoic Acid Receptors and Binding
Proteins in Human Skin, Department of Dermatology, The
University of Washington, Seattle
1993 Lecture, Psoriasis: Recent Molecular Genetic Clues, 10th
Annual Course for Consultants & Registrars, Brighton, U.K.
1993 Lecture, Molecular Genetics of Psoriasis, University of Kiel,
Kiel, Germany.
1993 Lecture, Basics of Genetic Linkage and Mapping: In Search of
the Psoriasis Gene, Overview of Molecular Biology Course,
American Academy of Dermatology
1994 Peter Horvath Lecture, The Genetics of Psoriasis, DC
Dermatologic Society Meeting, Washington, DC, 1994.
1995 Lecture, EGF receptor activation increases accumulation of
multiple EGF-like growth factors mRNAs by increasing mRNA
stability, Department of Dermatology, Nijmegen University,
Nijmegen, The Netherlands
1995 Keynote lecture, The Genetics of Psoriasis: HLA and Beyond,
Amsterdam Dermatological Society, Department of Dermatology,
University of Amsterdam, Amsterdam, The Netherlands, 1995.
1995 Lecture, The Genetics of Psoriasis: HLA and Beyond,
Department of Immunology, Kiel University, Kiel, Germany
1996 Lecture, Search for Psoriasis Genes: Genetics and Pathobiology,
The Jackson Laboratories, Second Mouse Skin and Hair Mutation
Meeting, Bar Harbor, ME
1996 Lecture, Molecular Genetics: the final answer?, Clinical
Dermatology 2000, Vancouver, Canada
1996 Lecture, The Molecular Genetics of Psoriasis, Clinical
Dermatology 2000, Vancouver, Canada
1997-2000 Lecture, Genetics of Psoriasis, HLA & Beyond, Focus Session,
American Academy of Dermatology
1997 Lecture, Genes and Cutaneous Inflammation - Psoriasis, The
World Congress of Dermatology, Sydney, Australia
1997 Lecture, Antenatal Diagnosis of Lamellar Ichthyoses, The World
Congress of Dermatology, Sydney, Australia.
1997 Lecture, Genetics of Psoriasis, HLA and Beyond ; Chair,
Genetics of Psoriasis Workshop, The World Congress of
Dermatology, Sydney, Australia
1997 Lecture, The Genetics of Psoriasis: HLA and Beyond, Grand
Rounds, Department of Dermatology, University of Cincinnati
1998 Lecture, Psoriasis is a genetic disease - how is it inherited?,
Course on Clinical Disease and its Molecular Basis, American
Academy of Dermatology, Orlando
1998 Louis Forman Lecture, Genetics of Psoriasis: HLA and Beyond,
St. John s Institute of Dermatology, London, UK
1998 Lecture, Early Events in Cutaneous Wound Healing, St. John s
Institute of Dermatology, London, UK
1998 Lecture, Genetics of Psoriasis: HLA and Beyond, Departments
of Dermatology and Genetics, University of Leicester, UK
1999 Audiotape Lecture, Genetics of Psoriasis, Dialogues in
Dermatology, American Academy of Dermatology
1999 Lecture, Signaling Networks Controlling Skin Re-
Epithelialization, Skin Diseases Research Center, Department of
Dermatology, Case Western University, Cleveland
James T. Elder, M.D., Ph.D. 4/14/11 10
1999 Lecture, Role of S100A2 in Keratinocyte Responses to Oxidative
Stress, Department of Pediatrics, University of Zurich,
Switzerland
2000 Ph.D. thesis opponent, for thesis entitled Genetic Susceptibility to
Psoriasis in Sweden, by Fredrik Enlund, Department of Clinical
Genetics, Faculty of Medicine, G teborg University, G teborg,
Sweden
2000 Lecture, The Search for PSORS1, the HLA-linked Genetic
Determinant of Psoriasis Susceptibility, Department of Clinical
Genetics, Sahlgrenska University Hospital, G teborg, Sweden
2001 Lecture, The Genetics of Psoriasis: A Clinician s Perspective,
Texas Dermatological Society Meeting, Houston, TX, May, 2001
2001 Lecture, The Genetics of Psoriasis: HLA and Beyond,
Department of Dermatology, University of Cape Town, South
Africa, August, 2001
2002 Lecture, What s New: Psoriasis, American Dermatological
Association Annual Meeting, Dallas, TX, September 29, 2002
2002 Lecture, Update on Dermatological Disorders: Eczema, Psoriasis,
and Acne, Flower Hospital, Sylvania, OH
2003 Lecture, Genetics of Psoriasis, Focus Session, American
Academy of Dermatology, San Francisco, CA, March 21, 2003
2003 PhD Thesis Opponent (Examiner) for thesis entitled Molecular
Genetics of Psoriasis, by Kati Asumalahti, Department of Human
Genetics, University of Helsinki, Helsinki, Finland
2006 Lecture, Common Dermatological Disorders, Toledo VA
Outpatient Clinic, Toledo, OH, December 6, 2006
2007 Lecture, Genetic Dissection of Psoriasis, Irvin H. Blank
Lecturer, Society for Investigative Dermatology, Los Angeles, CA,
May 9, 2007
2007 Lecture, Psoriasis: From Molecular Biology to Advances in
Therapeutics, Hospital de Clinicas, Montivideo, Uruguay,
September 28, 2007
2007 Lecture, Genetic Dissection of Psoriasis, Department of
Dermatology, University of Cincinnati, Cincinnati, OH October
25, 2007
2007 Lecture, Genetic Dissection of Psoriasis, Department of
Dermatology, University of Pennsylvania, Philadelphia, PA
November 1, 2007
2007 Lecture and Workshop, Genetic Skin Diseases, Society for
Investigative Dermatology, SID Basics of Skin: Pharmaceutics
and Pharmacology Course, Miami, FL, December 6, 2007
2009 Lecture, Molecular Dissection of Psoriasis: Integrating Genetics
and Biology, Baltic Summer School, Kiel, Germany, September
9, 2009
2009 Lecture, Twenty Years of Psoriasis Genetics: The Kiel-Ann
Arbor Connection, Department of Dermatology, Christian-
Albrechts University, Kiel, Germany, September 9, 2009
2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets
Immunology, Fine Lecture in Dermatology, Emory University,
March 20, 2010
2010 Lecture, Psoriasis: A Tale of Mice and Men, Jackson
Laboratories, Bar Harbor, MI, April 8, 2010
James T. Elder, M.D., Ph.D. 4/14/11 11
2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets
Immunology, University of Alabama at Birmingham, AL, May
12, 2010
2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets
Immunology, International Psoriasis Genetics Forum, Chinese
Society for Investigative Dermatology, Guangzhou, China, June
11, 2010
2010 Lecture, "Genetics and Pathogenesis of Psoriatic Arthritis", Second
International Congress on the Spondyloarthropathies, Gent,
Belgium, October 9, 2010
2011 Lecture, Complex Genetic Disorders: Pulling Back the Veil on
Human Disease, All India Institute of Medical Sciences, Delhi,
India, February 25, 2011
University of Michigan
1988 Lecture, Psoriasis, Department of Internal Medicine
1988-92 Lecture, Basics of Molecular Biology, Department of
Dermatology
1988-89 Mentor, Dermatology Resident Research, T Cell Receptor Gene
Rearrangements in Cutaneous T Cell Lymphoma, Vincent C. Ho,
M.D., Trainee.
1989 Lecture, Dermatologic Applications of Molecular Biology,
Michigan Dermatological Society, Ann Arbor, Michigan
1990 Mentor, Medical School Summer Research Project, Familial
Psoriasis, Stacie McMurtry, Trainee
1990-91 Mentor, Dermatology Fellow Research, Molecular Cloning of a
105 Kilodalton Basement Membrane Antigen, Lawrence Chan,
M.D., Trainee
1990 Seminar, The Economy of Keratinocyte Mitogens, Department
of Pathology Research Seminar Series
1991 Lecture, Molecular Genetics of Psoriasis, Michigan Derma-
tological Society Meeting
1991 Seminar, Expression of Retinoic Acid Receptors and Binding
Proteins in Human Skin, Graduate Program in Cellular and
Molecular Biology
1991 Lecture, T-Cell Receptor Gene Rearrangements, Department of
Dermatology
1992 Mentor, Medical Student Summer Research Project, CRABP-II
Responses to Natural and Synthetic Retinoids in Human Skin
Fibroblasts, Alex Kaplan, Trainee
1992-93 Mentor, Dermatology Resident Research, T Cell Cytokine
Expression in Psoriatic Lesions: Heterogeneity and Effects of
Cyclosporin A . Connie Ho, M.D., Trainee
1992 Lecture, DNA Repair: Mechanisms, Molecular and Syndromes,
Department of Dermatology
1992 Lecture, Regulation of Keratinocyte Growth, Department of
Dermatology
1992 Lecture, New Ideas about Old Drugs: Steroids, Retinoids, and
Vitamin D, Michigan Dermatological Society Meeting
1992-93 Lecture Series, Genodermatoses, Department of Dermatology
1993 Mentor, Medical Student Summer Research Project, Expression
of Calcineurin Isoforms in Human Skin, Edsel Kim, Trainee
James T. Elder, M.D., Ph.D. 4/14/11 12
1993 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Senior
Elective Course, Pharmacology and Therapeutics, Department of
Pharmacology
1993 Seminar, Positional Cloning of Epithelial Differentiation Genes,
Division of Nephrology, Department of Internal Medicine
1993 Lecture, Molecular Genetics of Psoriasis, Michigan Derma-
tology Society
1993 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Depart-
ment of Dermatology
1993 Lecture, Papulosquamous Dermatoses, MS III/IV Transitional
Series, Medical School
1993 Lecture, Infectious Skin Diseases, MS III/IV Transitional Series,
Medical School
1993 Lecture, Genetics of HLA-Associated Skin Diseases, Depart-
ment of Dermatology
1994 Lecture, Carcinogenesis, Department of Dermatology
1994 Lecture, Inherited Immunodefeciency Disorders, Department of
Dermatology
1994 Instructor, Live Patient Grand Rounds, Core Curriculum for
Second Year Medical Students
1994 Lecture, Genodermatoses, Core Curriculum for Second Year
Medical Students
1994 Lecture, The Genetics of Psoriasis, Graduate Cellular and
Molecular Biology Symposium
1995 Lecture, DNA Repair in Genodermatoses and Cancer,
Department of Dermatology
1995 Lecture, Bullous Genodermatoses, Department of Dermatology
1995 Lecture, Dermal Genodermatoses, Department of Dermatology
1995 Lecture, Hereditary Immunodeficiency Disorders, Department of
Dermatology
1995 Lecture, Epidermolysis Bullosa: Genetic Insights into Skin
Structure and Function, Core Curriculum for Second Year
Medical Students
1995 Instructor, Live Patient Grand Rounds, Core Curriculum for
Second Year Medical Students
1995 Lecture, Metabolic Disorders, Department of Dermatology
1996 Lecture, How do genetics influence psoriasis?, Michigan
Dermatological Society Meeting
1996 Examiner, Written Preliminary Examination in Pathobiology,
Graduate Program in Cellular and Molecular Biology
1996 Lecture, Introduction to Genodermatoses, Department of Derma-
tology
1996 Lecture, Photocarcinogenesis of Skin, Core Curriculum for
Second Year Medical Students
1996 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
1996 Lecture, Epidermolysis Bullosa: Genetic Insights into Skin
Structure and Function, Core Curriculum for Second Year
Medical Students
1996 Ph.D. Thesis committee, Andrea Lauer, School of Pharmacy
1996 Mentor, Lauren Gold, undergraduate, summer research
1996 Mentor, Annie Hiniker, undergraduate, summer research
James T. Elder, M.D., Ph.D. 4/14/11 13
1996 Oral preliminary examination committee, Yifeng Jia, Graduate
Program in Cellular and Molecular Biology
1997 Oral preliminary examination committee, Yifeng Jia, Graduate
Program in Cellular and Molecular Biology
1997 Lecture, Ichthyoses, Department of Dermatology
1997 Lecture, Acne Management: A Pore Man s Approach,
Department of Pediatrics, St. Joseph Mercy Hospital
1997 Lecture, EGF Receptor Tyrosine Kinase Activation in Cutaneous
Wound Healing, Center for Organogenesis
1997 Lecture, Immunopathogenesis of Psoriasis, Core Curriculum for
Second Year Medical Students
1997 Ph.D. Thesis Committee, Neti Waranuch, School of Pharmacy
1998 Lecture, Mechanisms of Regenerative Hyperplasia, Graduate
Program in Cellular and Molecular Biology Introductory Lecture
Series
1998 Lecture, ErbB Activation: A Critical Early Event in Would
Healing, Cancer Biology Research Seminar, Department of
Radiation Oncology and Comprehensive Cancer Center
1998 Lecture, Ichthyoses, Department of Dermatology
1998 Lecture, Fundamentals of Genetic Linkage, Department of
Dermatology
1998 Mentor, Sherbano Hasan, medical student, summer research
1998 Lecture, Cellular Immunology of the Skin, Core Curriculum for
Second Year Medical Students
1998 Lecture, Cutaneous Manifestations of HIV Infection, Core
Curriculum for Second Year Medical Students
1998 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
1998 Lecture, Molecular Mechanisms of Re-Epithelialization,
Graduate Course ACB 681, Organogenesis of a Complex Tissue
1999 Lecture, Postreceptor Signal Transduction Mechanisms in Wound
Healing and Cancer, Cancer Biology Research Seminar,
Department of Radiation Oncology, Comprehensive Cancer Center
1999 Lecture, S100A2 in Oxidative Stress and Carcinogenesis, Cancer
Genetics Research Seminar, Comprehensive Cancer Center
1999 Oral preliminary examination committee, Philip E. Schaner,
Graduate Program in Cellular and Molecular Biology
1999 Lecture, Hereditary Immunodeficiency Disorders, Department of
Dermatology
2000- Lecture, Genetics of Psoriasis, Department of Dermatology
Research Conference
1999 Lecture, Introduction to Immunology, Department of Derma-
tology
1999 Lecture, Cellular Immunology of the Skin, Core Curriculum for
Second Year Medical Students
1999 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2000 Lecture, Signal Transduction Pathways in Cutaneous Wound
Healing, Metastasis / Invasion Workshop, Comprehensive Cancer
Center
2000 Lecture, Molecular Mechanisms of Cutaneous Retinoid
Responsiveness, Department of Pediatrics Research Seminar
James T. Elder, M.D., Ph.D. 4/14/11 14
2000 Lecture, Genetics of Psoriasis, Cancer Biology Research
Seminar, Department of Radiation Oncology and Comprehensive
Cancer Center
2000 Lecture, Fine Mapping of PSORS1, the HLA-linked Component
of Psoriasis Susceptibility, Department of Dermatology
2001- Lecture, Inherited Immunodeficiency Disorders, Department of
Dermatology
2000 Mentor, Ladan Shahabi, medical student, summer research
2000 Lecture, The Search for Psoriasis Genes, Dermatology Sesqui-
centennial Grand Rounds
2000 Lecture, Cellular Immunology of the Skin, Department of
Dermatology
2000 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Department of Dermatology
2000 Lecture, Cellular Immunology of the Skin, Core Curriculum for
Second Year Medical Students
2000 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2000 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2001 Lecture, Expression and Function of Multiple ErbB Receptors in
Skin, Cancer Biology Research Seminar, Department of
Radiation Oncology and Comprehensive Cancer Center
2001 Lecture, Immunologic Hypersensitivity Reactions, Department
of Dermatology
2001 Lecture, Hereditary Immunodeficiency Disorders, Department of
Dermatology
2001 Lecture, Warts, Department of Dermatology
2001 Ph.D. Thesis Committee, Allison Moffa, Graduate School of
Cellular and Molecular Biology
2001 Lecture, Cellular Immunology of the Skin, Core Curriculum for
Second Year Medical Students
2001 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2001 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2002 Lecture, Cellular Immunology of the Skin, Department of
Dermatology
2002 Lecture, Hereditary Immunodeficiency Disorder, Department of
Dermatology
2002 Lecture, Genetics of Common Diseases, Department of
Dermatology
2002 Seminar, Molecular Genetics of Melanoma, Department of
Radiation Oncology, Division of Cancer Biology
2002 Lecture, BRAF Mutations in Melanoma, Department of
Dermatology
2002 Lecture, Introduction to Cutaneous Immunology, Department of
Dermatology
2002 Lecture, Cellular Immunology of the Skin, Core Curriculum for
Second Year Medical Students
2002 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2002 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
James T. Elder, M.D., Ph.D. 4/14/11 15
2003 Lecture, Genetics of Psoriasis: The MHC and Beyond,
Department of Human Genetics, University of Michigan
2003 Lecture, Introduction to Immunology, Department of
Dermatology
2003 Lecture, Hereditary Immunodeficiency Disorders . Department of
Dermatology
2003 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2003 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2004 Lecture, Autocrine Regulation of Keratinocyte Growth by EGF
Receptor Signaling, University of Michigan
2004 Qualifying exam committee chair for Nicole Willmarth, Graduate
Program in Cell and Molecular Biology, University of Michigan.
2004 Qualifying exam committee member for Jaemin Lee, Graduate
Program in Cell and Molecular Biology, University of Michigan.
2004 Thesis committee chairman for Nicole Willmarth, Graduate
Program in Cell and Molecular Biology, University of Michigan.
2004 Lecture, Genetic Analysis of Psoriasis and Psoriatic Arthritis,
Department of Dermatology
2004 Lecture, Immunopathogenesis of Psoriasis and Atopic
Dermatitis, Core Curriculum for Second Year Medical Students
2004 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2005 Lecture, Management of Common Dermatologic Conditions,
Clinical Pharmacology and Therapeutics Course, Department of
Pharmacology
2005 Lecture, Genetic Skin Disorders, Human Genetics 649,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
2005 Poster Judge, Graduate Program in Cellular and Molecular
Biology, 25th Annual Symposium and Poster Session
2005 Lecture, Genetic Dissection of PSORS1, Department of
Dermatology
2005 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2006 Lecture, Genetic Skin Disorders, Human Genetics 649,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
2006 Lecture, Genodermatoses: Insights into Skin Function, Part I,
Department of Dermatology
2006 Lecture, Genodermatoses: Insights into Skin Function, Part II,
Department of Dermatology
2006 Lecture, Identification of HLA-Cw6 as the Major Genetic
Determinant of Psoriasis Susceptibility, Department of Human
Genetics, University of Michigan
2006 Mentor, Johann Gudjonsson, MD, PhD, Dermatology Resident
2007 Mentor, Allen Bruce, MD, PhD, Dermatology Resident
2007 Lecture, Genetic Skin Disorders, Human Genetics 650,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
2007 Lecture, Genetics of Psoriasis: An Update, Department of
Dermatology, University of Michigan
James T. Elder, M.D., Ph.D. 4/14/11 16
2007 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2008 Lecture, Genetic Skin Disorders, Human Genetics 650,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
2008 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2009 Lecture, Genetic Skin Disorders, Human Genetics 650,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
2010 Lecture, "Common Skin Disorders", Dermatology Morning
Conference, July 19, 2010
2010 Kodachromes, "Pemphigus", Resident Book Club, Department of
Dermatology, July 30, 2010
2010 Instructor, Live Patient Grant Grounds, Core Curriculum for
Second Year Medical Students
2011 Lecture, Genetic Skin Disorders, Human Genetics 650,
Advanced Clinical Concepts in Medical Genetics, Department of
Human Genetics
EXTRAMURAL INVITED PRESENTATIONS
Cyclosporine Effects upon TPA-induced ODC Activity and mRNA Levels in
Hairless Mouse Skin, presentation, 2nd International Congress on Cyclosporine,
Washington, D.C., November 1987.
Growth Factors in Psoriasis, presentation, Ps
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