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High School Medical

Location:
New York, NY, 10065
Posted:
April 20, 2010

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Resume:

Judith Mesicek

The Rockefeller University, **** York Ave Box 362, New York, NY 10065

201-***-****, ***********@*****.***

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Education

2003-2010 Cornell University, Weill Graduate School of Medical Sciences New York, NY

(WGSMS)

Doctor of Philosophy, Pharmacology

Vincent duVigneaud Award of Excellence- Top Science and

Presentation (2008)

1997-2001 Colgate University Hamilton, NY

Bachelor of Arts, Biology (Honors)/ French, Cum Laude

Thesis Honors in Biology (2001), Beta Beta Beta National

Biological Honor Society- Tutor and Member, Dean's Award for

Academic Excellence (1999-2001)

Treasurer- Kappa Kappa Gamma Sorority

2000 UNIVERSIT DE BOURGOGNE Dijon,

Dijon Study Group- Selected Member France

French language and literature study program; English teacher

Research and Scientific Communication

2003-2010 MEMORIAL SLOAN KETTERING CANCER CENTER (MSKCC) New York, NY

Graduate Research Associate, Department of Pharmacology and

Molecular Therapeutics

Designed and implemented a gene overexpression /knockdown

approach to enhance/decrease sensitivity of human tissues to

radiation providing a novel cancer therapeutic strategy

Initiated and participated in multiple scientific

collaborations based on research discoveries

Authored 3 published manuscripts and 1 currently in review in

highly ranked journals

Designed and presented slide decks and posters at international

conferences

2001-2003 WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY New York, NY

Research Technician, Department of Pharmacology

Applied methodologies to study TCDD toxicity and its regulation

of cytochrome P-450 expression

Trained and supervised both research technicians and

undergraduate students

Managed laboratory finances and inventory

2000, 2001 SCHERING-PLOUGH RESEARCH INSTITUTE Kenilworth,

Summer and Winter Intern, Department of Tumor Biology NJ

Implemented newly acquired confocal microscope to study

localization and expression of the CXCR2 receptor in human

endothelial cells as a novel angiogenic target

Authored in-house user manual for confocal hardware and

software for colleagues

Teaching, Leadership, and Non-Scientific Communication

2008 VERITAS TUTORS New York, NY

Chemistry Tutor

Advised and educated high school students for SAT Chemistry

Subject Test

2007, 2008 SUMMER ACADEMY IN MOLECULAR BIOLOGY, WGSMS New York, NY

Instructor

Trained public high school science teachers to improve the

design and delivery of classroom laboratory modules

Educated New York City high school students in scientific

concepts and techniques

2004-2006 VINCENT DU VIGNEAUD SYMPOSIUM, WGSMS New York, NY

Abstract Committee Chair

Organized and designed the scientific symposium abstract book

and program

Social Committee Co-Chair

Arranged pre- and post-symposium social events for keynote

speaker and 400+ attendees

2000 Lyc e European Charles De Gaulle Dijon,

Instructor France

Created and executed lesson plans in English language and

American culture for primary and secondary school students

Languages

English (native), French (proficient), Spanish (beginner)

Computer

Skills

Fluent in both PC and Mac systems, including the following

software suites: MS Office (Word, Excel, Powerpoint,

Publisher), GraphPad Prism, EndNote, Adobe Suite (Photoshop,

Acrobat, Illustrator), Internet Browsers: Internet Explorer,

Netscape, Safari, Firefox.

Publications

Judith Mesicek, Hyunmi Lee, Taya Feldman, Xuejun Jiang, Anastasia

Skobeleva, Evgeny Berdyshev, Adriana Haimovitz-Friedman, Zvi Fuks, and

Richard Kolesnick. (2010) Ceramide Synthases 2, 5, and 6 Confer Distinct

Roles in Radiation-induced Apoptosis in HeLa Cells. Cellular Signalling,

accepted for publication.

Jimmy A. Rotolo, Judith Mesicek, Jerzy Maj, John-Philip Truman, Adriana

Haimovitz-Friedman, Richard Kolesnick, and Zvi Fuks. (2010) Regulation of

Ceramide Synthase-Mediated Crypt Epithelium Apoptosis by DNA Damage Repair

Enzymes. Cancer Research 70(3):957-967.

Hyunmi Lee, Judith Mesicek, Jimmy A. Rotolo, Wen-Chieh Liao, Andreas

Rimner, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins,

Dayong Zhai, John C. Reed, Adriana Haimovitz-Friedman, Zvi Fuks, and

Richard Kolesnick. Ionizing radiation remodels mitochondrial membranes to

facilitate Bax insertion. Manuscript currently in review.

Sujoy Lahiri, Hyunmi Lee, Judith Mesicek, Zvi Fuks, Adriana Haimovitz-

Friedman, Richard N. Kolesnick, and Anthony H. Futerman. (2007) Kinetic

Characterization of Mammalian Ceramide Synthases: Determination of Km

Values Towards Sphinganine. FEBS Letts 581(27):5289-5294.

Presentations and Posters

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks

and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in

Radiation-induced Apoptosis". Weill Cornell Graduate School Pharmacology

Retreat, Skytop, Pennsylvania, May 2009.

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks

and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in

Radiation-induced Apoptosis". Charleston Ceramide Conference, Charleston,

South Carolina, March 2009.

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks

and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in

Radiation-induced Apoptosis". 28th Annual Vincent duVigneaud Memorial

Symposium, New York, New York, May 2008.

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks

and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in

Radiation-induced Apoptosis". Oral presentation at Weill Cornell Graduate

School Pharmacology Retreat, Skytop, Pennsylvania, May 2008.

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Zvi Fuks and Richard

Kolesnick. "Elucidating the Role of Ceramide Synthase in Radiation-induced

Apoptosis". 27th Annual Vincent duVigneaud Memorial Symposium, New York,

New York, May 2007.

Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Zvi Fuks and Richard

Kolesnick. "Elucidating the Role of Ceramide Synthase in Radiation-induced

Apoptosis" Oral presentation at the Charleston Ceramide Conference, Pacific

Grove, California, March 2007.

Judith Mesicek, Hyunmi Lee, Zvi Fuks and Richard Kolesnick "Cloning and

Characterization of Human Ceramide Synthase". Weill Graduate School

Pharmacology Retreat. April 2004, March 2005, May 2006. 24th Annual Vincent

duVigneaud Memorial Symposium, New York, New York, May 2004.

Judith Mesicek and Arleen Rifkind. "Constitutive Expression of CYP1A5 in

Cultured Primary Chick Embryo Hepatocytes". Weill Cornell Graduate School

Pharmacology Retreat. April 2003.

Judith Mesicek, Michael Malkowski, and Lydia Armstrong. "3D Analysis of GFP-

CXCR2 Expression and Subcellular Organelle Localization of HEK-293 Cells".

SPRI Summer Intern Poster Session, Kenilworth, New Jersey, August, 2000.

Judith Mesicek, Matt DiVisconte, and Barbara Hoopes. "The Role of Internal

Initiation of Translation in Expression of the TATA-Binding Protein in S.

cerevisae". Colgate University Biology Department Poster Session, Hamilton,

New York, December, 1999. Honors Degree in Biology Thesis Defense, May

2001.



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