Judith Mesicek
The Rockefeller University, **** York Ave Box 362, New York, NY 10065
201-***-****, ***********@*****.***
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Education
2003-2010 Cornell University, Weill Graduate School of Medical Sciences New York, NY
(WGSMS)
Doctor of Philosophy, Pharmacology
Vincent duVigneaud Award of Excellence- Top Science and
Presentation (2008)
1997-2001 Colgate University Hamilton, NY
Bachelor of Arts, Biology (Honors)/ French, Cum Laude
Thesis Honors in Biology (2001), Beta Beta Beta National
Biological Honor Society- Tutor and Member, Dean's Award for
Academic Excellence (1999-2001)
Treasurer- Kappa Kappa Gamma Sorority
2000 UNIVERSIT DE BOURGOGNE Dijon,
Dijon Study Group- Selected Member France
French language and literature study program; English teacher
Research and Scientific Communication
2003-2010 MEMORIAL SLOAN KETTERING CANCER CENTER (MSKCC) New York, NY
Graduate Research Associate, Department of Pharmacology and
Molecular Therapeutics
Designed and implemented a gene overexpression /knockdown
approach to enhance/decrease sensitivity of human tissues to
radiation providing a novel cancer therapeutic strategy
Initiated and participated in multiple scientific
collaborations based on research discoveries
Authored 3 published manuscripts and 1 currently in review in
highly ranked journals
Designed and presented slide decks and posters at international
conferences
2001-2003 WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY New York, NY
Research Technician, Department of Pharmacology
Applied methodologies to study TCDD toxicity and its regulation
of cytochrome P-450 expression
Trained and supervised both research technicians and
undergraduate students
Managed laboratory finances and inventory
2000, 2001 SCHERING-PLOUGH RESEARCH INSTITUTE Kenilworth,
Summer and Winter Intern, Department of Tumor Biology NJ
Implemented newly acquired confocal microscope to study
localization and expression of the CXCR2 receptor in human
endothelial cells as a novel angiogenic target
Authored in-house user manual for confocal hardware and
software for colleagues
Teaching, Leadership, and Non-Scientific Communication
2008 VERITAS TUTORS New York, NY
Chemistry Tutor
Advised and educated high school students for SAT Chemistry
Subject Test
2007, 2008 SUMMER ACADEMY IN MOLECULAR BIOLOGY, WGSMS New York, NY
Instructor
Trained public high school science teachers to improve the
design and delivery of classroom laboratory modules
Educated New York City high school students in scientific
concepts and techniques
2004-2006 VINCENT DU VIGNEAUD SYMPOSIUM, WGSMS New York, NY
Abstract Committee Chair
Organized and designed the scientific symposium abstract book
and program
Social Committee Co-Chair
Arranged pre- and post-symposium social events for keynote
speaker and 400+ attendees
2000 Lyc e European Charles De Gaulle Dijon,
Instructor France
Created and executed lesson plans in English language and
American culture for primary and secondary school students
Languages
English (native), French (proficient), Spanish (beginner)
Computer
Skills
Fluent in both PC and Mac systems, including the following
software suites: MS Office (Word, Excel, Powerpoint,
Publisher), GraphPad Prism, EndNote, Adobe Suite (Photoshop,
Acrobat, Illustrator), Internet Browsers: Internet Explorer,
Netscape, Safari, Firefox.
Publications
Judith Mesicek, Hyunmi Lee, Taya Feldman, Xuejun Jiang, Anastasia
Skobeleva, Evgeny Berdyshev, Adriana Haimovitz-Friedman, Zvi Fuks, and
Richard Kolesnick. (2010) Ceramide Synthases 2, 5, and 6 Confer Distinct
Roles in Radiation-induced Apoptosis in HeLa Cells. Cellular Signalling,
accepted for publication.
Jimmy A. Rotolo, Judith Mesicek, Jerzy Maj, John-Philip Truman, Adriana
Haimovitz-Friedman, Richard Kolesnick, and Zvi Fuks. (2010) Regulation of
Ceramide Synthase-Mediated Crypt Epithelium Apoptosis by DNA Damage Repair
Enzymes. Cancer Research 70(3):957-967.
Hyunmi Lee, Judith Mesicek, Jimmy A. Rotolo, Wen-Chieh Liao, Andreas
Rimner, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins,
Dayong Zhai, John C. Reed, Adriana Haimovitz-Friedman, Zvi Fuks, and
Richard Kolesnick. Ionizing radiation remodels mitochondrial membranes to
facilitate Bax insertion. Manuscript currently in review.
Sujoy Lahiri, Hyunmi Lee, Judith Mesicek, Zvi Fuks, Adriana Haimovitz-
Friedman, Richard N. Kolesnick, and Anthony H. Futerman. (2007) Kinetic
Characterization of Mammalian Ceramide Synthases: Determination of Km
Values Towards Sphinganine. FEBS Letts 581(27):5289-5294.
Presentations and Posters
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks
and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in
Radiation-induced Apoptosis". Weill Cornell Graduate School Pharmacology
Retreat, Skytop, Pennsylvania, May 2009.
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks
and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in
Radiation-induced Apoptosis". Charleston Ceramide Conference, Charleston,
South Carolina, March 2009.
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks
and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in
Radiation-induced Apoptosis". 28th Annual Vincent duVigneaud Memorial
Symposium, New York, New York, May 2008.
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Evgeny Berdyshev, Zvi Fuks
and Richard Kolesnick. "Elucidating the Role of Ceramide Synthase in
Radiation-induced Apoptosis". Oral presentation at Weill Cornell Graduate
School Pharmacology Retreat, Skytop, Pennsylvania, May 2008.
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Zvi Fuks and Richard
Kolesnick. "Elucidating the Role of Ceramide Synthase in Radiation-induced
Apoptosis". 27th Annual Vincent duVigneaud Memorial Symposium, New York,
New York, May 2007.
Judith Mesicek, Hyunmi Lee, Anthony H. Futerman, Zvi Fuks and Richard
Kolesnick. "Elucidating the Role of Ceramide Synthase in Radiation-induced
Apoptosis" Oral presentation at the Charleston Ceramide Conference, Pacific
Grove, California, March 2007.
Judith Mesicek, Hyunmi Lee, Zvi Fuks and Richard Kolesnick "Cloning and
Characterization of Human Ceramide Synthase". Weill Graduate School
Pharmacology Retreat. April 2004, March 2005, May 2006. 24th Annual Vincent
duVigneaud Memorial Symposium, New York, New York, May 2004.
Judith Mesicek and Arleen Rifkind. "Constitutive Expression of CYP1A5 in
Cultured Primary Chick Embryo Hepatocytes". Weill Cornell Graduate School
Pharmacology Retreat. April 2003.
Judith Mesicek, Michael Malkowski, and Lydia Armstrong. "3D Analysis of GFP-
CXCR2 Expression and Subcellular Organelle Localization of HEK-293 Cells".
SPRI Summer Intern Poster Session, Kenilworth, New Jersey, August, 2000.
Judith Mesicek, Matt DiVisconte, and Barbara Hoopes. "The Role of Internal
Initiation of Translation in Expression of the TATA-Binding Protein in S.
cerevisae". Colgate University Biology Department Poster Session, Hamilton,
New York, December, 1999. Honors Degree in Biology Thesis Defense, May
2001.