Project Assistant

Melissa A. Krupski-Downs, Ph.D.

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WORK EXPERIENCE

Albert Einstein College of Medicine - Bronx, New York

Technology Marketing Intern - Offices of Biotechnology and Business

Development (February 2010 - August 2010)

. Create value propositions and marketing briefs for the patented claims

of novel technologies developed by Einstein faculty-inventors.

. Market these technologies to companies chosen through industry

research for the purpose of executing licensing agreements. Efforts

have resulted in ongoing dialogue with potential licensees.

. Completed the NCET2 Research Commercialization Introductory Course.

Post-doctoral fellow - Department of Cell Biology

(September 2009 - March 2010)

. Initiated and led a project to investigate how BCL6 mutations may

affect the success of lymphoma therapies.

Graduate Student - Department of Cell Biology

(January 2003 - September 2009)

. Examined the role of the BCL6 protein in the generation of lymphomas -

thesis project.

. Collaborated frequently on projects outside of my thesis work

resulting in two separate publications.

. Recruited and organized the visits of guest speakers to the campus as

a member of the Student Invited Speaker Group. Initiated improvements

in this process that continue to be implemented.

. Delivered presentations regarding my research regularly, in addition

to presenting the current literature as a member of the Departmental

Journal Club.

. Managed and mentored summer and rotation students entering the lab.

Graduate Rotation Student - Department of Pathology

(October 2002 - December 2002)

. Examined the drug 7-hydroxystaurosporine (UCN-01) as a potential agent

for the treatment of neuroblastoma resulting in a publication.

University of Delaware - Newark, Delaware

Undergraduate Research Assistant - Department of Biological Sciences

(September 2000 - June 2002)

. Characterized a novel protein to assess its involvement in breast

cancer development.

Resident Assistant - Department of Residence Life

(August 2000 - May 2002)

. Upheld university policies within the dormitories while developing and

maintaining a harmonious community.

. Conceptualized and delivered educational programs and social events

for the benefit of the residents while also serving as a resource and

mentor.

. Initiated and planned team building activities to foster and maintain

the relationships between my fellow staff members.

Cornell Cooperative Extension - Southold, New York

Research Intern

(June 1996 -

June 1998)

. Developed and implemented a strategy to help replenish the depleting

local scallop population. Recognized with an award from the

Westinghouse Project Competition.

EDUCATION

Albert Einstein College of Medicine - Bronx, New York

(August 2002 - September 2009)

Ph.D., Cell Biology, September 2009; M.Sc., Cell Biology, May 2004

University of Delaware - Newark, Delaware

(August 1998 - May 2002)

Honors B.A., Biology Minor: Philosophy, May 2002

. Selected Honors/Awards: Dean's List ('98 - '02), Golden Key National

Honor Society Member, Charles Peter White Fellow, University of

Delaware Honors Program Scholarship ('98 - '02)

SKILLS

. Microsoft Office

. Familiar with market subscription services such as MedTRACK and

Knowledge Express.

. Laboratory skills: Ten years of molecular biology, tissue culture, and

genetic technical experience.

PUBLICATIONS

Krupski-Downs M, Yu JJ, Ding BB, Chan H and Ye BH. A novel coding region

mutation reveals a tumor-suppressive function for BCL6 in lymphomagenesis.

Manuscript in preparation.

Peled, J.U., Yu, J.J., Venkatesh, J., Ding, B.B., Krupski-Downs, M.,

Shaknovich, R., Sicinski, P., Diamond, B., Scharff, M.D., Ye, B.H. (2010)

Requirement for cyclin D3 in germinal center formation and function. Cell

Research. 6:631-46

Mendez LM, Polo JM, Yu JJ, Krupski M, Ding BB, Melnick A, Ye BH. (2008)

CtBP is an essential corepressor for BCL6 autoregulation. Mol Cell Biol.

7:2175-86

Shankar S., Krupski M., Parashar B., Okwuaka C., O'Guin K., Mani S., and

Shafit-Zagardo B. (2004) UCN-01 alters phosphorylation of Akt and GSK3and

induces apoptosis in six independent human neuroblastoma cell lines. J.

Neurochem. 90:702-11.

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