DR. DIVYESH N. NAGAR

Phone: +91-982**-*****

Email: hf8n0l@r.postjobfree.com

Objective

Pursue a goal to be a scientist in pharmaceutical chemistry in Research and Development.

Education

Doctor of Philosophy (Organic Chemistry) November, 2002 (Degree awarded)

Department of Chemistry, Saurashtra University, Rajkot –360 005, Gujarat, India.

Thesis Title: “Studies on Compounds of Therapeutic Interest”

Master of Science (Pharmaceutical Chemistry) May, 1997

Department of Chemistry, Saurashtra University, Rajkot –360 005, Gujarat, India

Bachelor of Science (Chemistry) April, 1995

Department of Chemistry, Saurashtra University, Rajkot –360 005, Gujarat, India

Professional Experience 10 Years

Team Leader (Research & Development) May 2007 –continue

Alembic Research Centre, Vadodara, Gujarat, India

Research Scientist (Research & Development) May 2005 - May 2007

Jubilant Organosys Limited, Noida, UP, India.

Sr. Executive (Research & Development) June 2002 - May 2005

Alembic Limited, Vadodara, Gujarat, India.

Research Officer (Research and Development) March 2001 - June 2002

Uma Laboratories Pvt. Ltd, Vadodara, Gujarat, India.

Best Paper Award : Prof. K. A. Thaker award for best paper in 2002.

Patent : WO2009007988A1

Alembic Limited, Vadodara, Gujarat, India.

Projects

Technology Transferred Projects

Dronedarone hydrochloride (under pipeline)

Rizatriptan (under pipeline)

Zolmitriptan (under pipeline)

Pentosan Polysulfate sodium (polymer based drug)

Armodafinil

Topiramate

Erythromycin (EP)

Rivastigmine Tartrate

Azithromycin

Clarithromycin

Erythromycin Estolate (EP)

Erythromycin Phosphate

Venlafaxine hydrochloride

Skill and Arts

10 year Synthetic and analytical experience in API Generic Research

Scale up operations, Process Validation, Process Controls, and Documentation as per guideline.

Knowledge of QA, GMP and Regulatory Affairs

Impurity Profile Study

Crystallization and Isolation Method i.e. Chromatron, Flash Chromatography,

Column Chromatography,

Analytical instrument experience HPLC, IR, UV, GC, Mass, lyophilizer etc.

Knowledge of NMR Interpretation, FT-IR, Mass Fragmentation, DSC, XRD etc.

Knowledge of ICH, USFDA guidelines

Technology Transfer Documents, DMF etc.

Research Activity done during Ph.D.

Anti-histamine drug: Phenothiazine moiety

Synthesis, Characterizations and Biological evaluations of the following compounds such as,

5-imidazolinone Phenothiazine derivatives

Mannish bases of Phenothiazine derivatives

1,3-disubstituted-2-propene-1-ones derivatives (Chalcon)

5-Pyrazoline derivatives

Acetyl-5- Pyrazoline derivatives

Cyanopyridine derivatives

Cyanopyran derivatives

Isoxazoline derivatives

Benzodiazepine derivatives

Pyranopyrazoline derivatives

Pyridopyrazoline derivatives

Thiodioxopyrimidine derivatives

Trioxopyrimidine derivatives

Nitriles & Acetamido derivatives

Publications

Paper Publications

1. T H Pavagadhi, Divyesh N Nagar and V H Shah*, Synthesis and antimicrobial activity of some new 3-aryl-5- (m-phenoxy phenyl)-isoxazoles, Oriental. J Chemistry, 17 (2), 311 (2001).

2. T H Pavagadhi, Divyesh N Nagar and V H Shah*, Microwave assisted synthesis and biological evaluation of some new 3-n-[p-(acetophenyl amino sulpho)-phenyl]-2-aryl-5-h / methyl-4-thiazolidinones, Oriental. J Chemistry, 18 (2), (2002).

3. D N Nagar, Tushar Mehta and V H Shah*, Heterocyclic system containing nitrogen atoms: synthesis, spectral characterization and biological evaluation of 4-aryl-2- (p-benzoylaminophenyl)-3,3,4,5-tetrahydro- [1,5]- benzodiazepines, Oriental. J Chemistry, 18 (3), (2002).

4. D N Nagar, Tushar Mehta and V H Shah*, A facile generation of pyranopyrazoles: synthesis of 2-amino-3-cyano-4,5-dimethyl-7-n-phenyl-4-(p-aroylaminophenyl)-pyrano-[2,3-d]-pyrazoles, Oriental. J Chemistry, 18 (3), (2002).

5. D N Nagar, Tushar Mehta and V H Shah*, Synthesis, spectral characterization and antimicrobial evaluation of some new 2-pyrazolines, Oriental. J Chemistry, 18 (3), 525-528 (2002).

6. D N Nagar, K H Sikotra and V H Shah, Synthesis and antimicrobial activity of 1-(p-acetamido-phenylsulphonamido)-2-Thioxo-5-Cyano-6-Aryl/2-ChloroSubstituted Quinolinyl-3-yl- (1H)-Pyrimidines, J. Inst. Chemists 73 (III), 112 (2001).

7. D N Nagar, K H Sikotra and V H Shah, 3,7-Bis- (4’-arylidene-2’-phenyl-5’-oxo imidazol-1’-yl)-phenothiazine, J. Inst, Chemists; 73(2), 64 (2001).

8. D N Nagar, and V H Shah, Synthesis and spectral studies of 1-[(p)-acetophenyl sulphonamido phenyl]-2-phenyl-4-arylidene imidazole-5-ones, J. Inst. Chemists,

Vol. 73 (3), 103 (2001)

9. D N Nagar, and V H Shah, Synthesis and spectral studies of 5-methyl-2-thioxo-6-aryl-4- (2’-hydroxy-5’-chloro- phenyl amino carbonyl) pyrimidines, J. Inst. Chemists

Vol. 73 (4), 138 (2001)

10. D N Nagar, and V H Shah, Studies on 3-aryl-1- (p-benzoylaminophenyl)-2-propene-1-ones, J. Inst. Chemists, Vol. 74 (3), (2002).

11. D N Nagar, and V H Shah, Studies on a-p- (4-acetophenylamino sulphophenyl)-aminoacetonitriles, J. Inst. Chemists, Vol. 74 (3), (2002).

12. D N Nagar, and V H Shah, Studies on some new trioxopyrimidines, J. Inst. Chemists (India), Vol. 74 (4), (2002).

13. D N Nagar, and V H Shah, Studies on some new thiodixopyrimidines, J. Inst. Chemists, Vol. 74 (4), (2002).

14. D N Nagar, and V H Shah, Facile generation of pyridopyrazoles: Synthesis of 3-amino-4-aryl-6- (p-benzoylaminophenyl)-pyrido-/2,3-d/ -1-H-pyrazoles, J. Inst. Chemists, Vol. 74 (4), (2002).

15. D N Nagar, and V H Shah, Facile generation of pyridopyrazoles: Synthesis of 3-amino-4-aryl-6- (p-benzoylaminophenyl)-pyrido-/2,3-d/ -1-N-phenyl pyrazoles, J. Inst. Chemists, Vol. 74 (4), (2002).

Poster Paper Presentation

Research paper presented in “IInd INTERNATIONAL SYMPOSIUM ON MOLECULAR MEDICINE” organized by Sun Pharma Advanced Research Center, M.S. University of Baroda and State University of New York at Buffallo from January 20th –23rd 2002.

Research article presented in “International Conference on Heterocyclic Chemistry” held at University Rajashthan Jaipur (India) from December 15-18, 2001.

Research Paper presented in “Second All Gujarat Research Scholars Meet” organized by Indian Chemical Society, Vadodara Chapter at M S University Vadodara on 25th February 2001.

Research article presented in “National Symposium between University and Industry Interaction “held at Saurashtra University, Rajkot from March 22nd to 23rd 1999.

Activity

1. National and International Journal reading

2. Knowledge of ChemSketch structure drawing Software etc.

3. Sport games e.g. Cricket, Badminton, Volley-ball

4. National service scheme: Tree Plantation to make the university green and beautiful

Computer Literacy

1. Certificate of “Computer course of information technology for researchers”

2. Certificate of “ Introduction of windows 98 and MS office 2000”

3. Seminar on “ Use of computer & information technology in research”

4. Seminar on “ A training on advance computer and information technology for researchers”

Personal Profile

Date of Birth : 01.01.1974

Height : 163 cm

Marital Status : Married

Children : Child (one)

Nationality : Indian

Address : Chemical Research Laboratory,

Saurashtra University, Rajkot-360 005.

Gujarat, India.

Voice Phone : +91-982**-***** (Work)

Email : hf8n0l@r.postjobfree.com

References

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Dr. V H Shah Associate Professor, Dept of Chemistry, Saurashtra University, Rajkot – 360 005. Gujarat, India. Tel. 028*-******* Dr. Anamik K ShahAssociate Professor,Dept of Chemistry,Saurashtra University,Rajkot – 360 005.Gujarat, India.Tel. +91 281 2576006M: +91-982******* Dr. Ashutosh AgarwalPresident,R & D (Organic)Jubilant Organosys Ltd,Corporate Office,Noida.U. P., India.M: +91-981*******

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