Curriculum Vitae, Alireza Ebrahimnejad, PhD

Alireza Ebrahimnejad, PhD

**** **** ****. ***. **. 17

Palo Alto, CA, 94306

Phone :650-***-****

E-mail: dzuypm@r.postjobfree.com

Personal Information:

• Permanent resident: United States of America

• Citizenship: Germany

Objective: Seeking the position as Scientist

Highly creative scientist with an extensive experience in preclinical _xenografts / orthotopic_ models of human cancers and development of targeted oncology therapeutics, system biology, in vivo xenogen imaging (bioluminescence & microPET), immunohistochemistry / immunofluorescence

Summary of Qualifications:

• Profound experience in field of cancer research and target discovery and validation, system biology, cell biology, molecular biology, signal transduction and protein purification & analysis,

• In vivo xenogen imaging (bioluminescence & micro PET), surgical procedures

• Laser capture microdissection, immunohistochemistry,

• In depth knowledge of laboratory techniques (ELISA, FACS, cell culture & RNA expression analysis)

• Sound know how of standard protein assays, qRT-PCR, migration and invasion

• Skilled professional at interpreting research outcome & leading research assignments

• Managing and leading several research projects,

• Exceptional organizational & problem-solving skills

• Profound ability to prepare research reports for publications

• Excellent computer skills combined with statistical skills

Professional Experience:

Consulting Scientist, CA 2009-present

Stanford Medical School, Department of Pathology, CA

2007 -2009

Postdoctoral researcher

• Development of new biomarker for leukemia cutis and acute myeloid leukemia

Stanford Medical School, Department of Radiology and Bio-X, CA

2006-2007

Postdoctoral researcher

• Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice

University Hospital Hamburg Eppendorf, Department of Clinical Chemistry, Hamburg, Germany & Department of Ophthalmology, Hospital Eye University, Dresden, Germany 2002-2005

Scientist

• Investigation of skin and choroidal melanoma and its invasion ability in ex vivo model

University Hospital Hamburg Eppendorf, Department of Clinical Chemistry, Hamburg, Germany & Department of Ophthalmology, Hospital Eye University, Dresden, Germany 2002-2004

Scientist

• Inhibition of neovascularization by mycophenolate mofetil (MMF) in cornea

Awards:

• Child Health Research Program (Lucile Packard Children’s Hospital/Stanford University). 2007-2008

• National Institute of Biochemical Imaging and Bioengineering (NIBB) (R21 EB001785).

2006-2007

• German Research Foundation (DFG & SFB). 2003-2005

Publications:

Cai1, W., Ebrahimnejad1, A., Cao, Q., Chen, K., Tice, D., Chen, Xiaoyuan. 2007. Quantitative Radio- ImmunoPET imaging of EphA2 in Living Mice Eur J Nucl Med Mol Imaging. 2007 Dec; 34(12):2024-36. Epub 2007 Aug 3

Chalajour, F., Treede, H., Gehling, UM., Ebrahimnejad, A., Boehm, DH., Riemer, RK., Ergun, S., Reichenspurner, H. 2007. Identification and characterization of cells with high angiogenic potential and transitional phenotype in calcific valve. Exp Cell Res. 313(11):2326-35. Epub 2007 Mar 14.

Ebrahimnejad, A., Streichert, T., Nollau, P., Horst, A.K., Wagener, C., Bamberger, A.M., and Brummer, J. 2004. CEACAM1 enhances invasion and migration of melanocytic and melanoma cells. Am J Pathol. 165:1781-1787.

Ebrahimnejad, A., Flayeh, R., Unteregger, G., Wagener, C., and Brummer, J. 2000. Cell adhesion molecule CEACAM1 associates with paxillin in granulocytes and epithelial and endothelial cells. Exp Cell Res. 260:365-373.

Streichert, T., Ebrahimnejad, A., Ganzer, S., Flayeh, R., Wagener, C., and Brummer, J. 2001. The microbial receptor CEACAM3 is linked to the calprotectin complex in granulocytes. Biochem Biophys Res Commun. 289:191-197.

Brummer, J., Ebrahimnejad, A., Flayeh, R., Schumacher, U., Loning, T., Bamberger, A.M., and Wagener, C. 2001. cis Interaction of the cell adhesion molecule CEACAM1 with integrin beta(3). Am J Pathol. 159:537-46.

Chalajour, F., Treede, H., Ebrahimnejad, A., Lauke, H., Reichenspurner, H., and Ergun, S. 2004. Angiogenic activation of valvular endothelial cells in aortic valve stenosis. Exp Cell Res. 298:455-64.

Ergun, S., Kilic, N., Wurmbach, J.H., Ebrahimnejad, A., Fernando, M., Sevinc, S., Kilic, E., Chalajour, F., Fiedler, W., Lauke, H., Lamszus, K., Hammerer, P., Weil, J., Herbst, H., and Folkman, J. 2001. Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes. Angiogenesis. 4:193-206.

Boehle, A.S., Kurdow, R., Schulze, M., Kliche, U. Sipos, B., Soondrum, K., Ebrahimnejad, A., Dohrmann, P., Kalthoff, H., Henne-Bruns, D., and Neumaier, M. 2001. Human endostatin inhibits growth of human non-small-cell lung cancer in a murine xenotransplant model. Int J Cancer. 94:420-428.

Books:

Brümmer, J., Ganzer, S., Ebrahimnejad, A., Flayeh, A., Streichert, T., and C. Wagener (1996). The CD66 Complex: Activation of tyrosine kinase of the Src family. Tissue Antigens, 48, 427.

Works Currently in Progress:

Ebrahimnejad, A., Chalajour, F., George, TI, Sundram, U. Runx1, the mediator in pathogenesis of Leukemia Cutis

Technical and Specialized Skills:

Preclinical study (development of tumor models) and surgery

In vivo imaging (bioluminescence and micro PET)

Laser capture micro dissection

Immunohisto- and Immunocytochemical analysis

In vitro assays (e.g. migration-, invasion-, tube formation- and proliferation assay)

Purification of Proteins & Antibodies (in preparative scale)

Design, Cloning, Expression and purification of recombinant proteins

Protein Binding Studies, ELISA, FACS

Molecular biology (RNA expression analysis, isolation and amplification, qRT- PCR)

Research Interests:

Cancer research

Signal transduction

Angiogenesis

Education:

• University Konstanz / University Hospital Hamburg Eppendorf, Germany Doctor of Science (Biochemistry, Cell Biology, Genetics)

2003

Contact this candidate