Little Rock Full Time

Samuel Kakraba

https://scholar.google.com/citations?user=xC4ng54AAAAJ&hl=en

Work Address: 629 Jack Stephens Drive, Room

****, ****** ****, ** *****, U.S.A

Email: adx1uk@r.postjobfree.com, adx1uk@r.postjobfree.com

Phone: 501-***-****

Residential Address: 503 N. Pine St, Apt 5,

Little Rock, AR 72205, U.S.A

EDUCATION

University & Address Degree Awarded &

Date

Research/Thesis Research Specialty

The University of

Arkansas for Medical

Sciences & the Univ. of

Arkansas at Little

Rock, Little Rock, AR

72205, U.S.A.

Ph.D.(Bioinformatics)

August 2015 - present

Drugs that Protect

Against Protein

Aggregation in

Neurodegenerative

Diseases

Main advisor:

Professor Robert

J.S Reis

Research Areas:

Computational Sciences

Aging

Data Science

Machine Learning

Drug Discovery

Applied mathematics & statistics

Molecular modeling

East Tennessee State

University, Johnson

City, Tennessee, TN

37604, U.S.A.

M.S. (Mathematical

Sciences)

August 2013 – May,

2015

A Hierarchical

Graph for

Nucleotide Binding

Domain 2”

Main advisor:

Professor Debra J.

Knisley

Research Areas:

Computational Sciences

Graph-theoretic Modeling of

Biological Networks

Applied Discrete Mathematics

Mathematical Modeling

Computational Biology

Applied Statistics

Epidemiology

Bioinformatics

University of Cape

Coast, Cape Coast,

Central Region, Ghana,

West Africa

B.Ed.(Mathematics)

August 2007 –

May,2011

The Relationship

Between Students’

Perception and

their Mathematics

Achievement in the

Senior High

Main Advisor:

Mr. Benjamin Y.

Sokpe

Research Areas:

Mathematics

Statistics

Education

GRADUATE LEVEL COURSES

AREA OF STUDY COURSES CREDITS

STATISTICS&

BIOSTATISTICS

Categorical Data Analysis 3

Statistical Methods I 3

Statistical Methods II 3

Multivariate Statistics 3

BIOINFORMATICS/

COMPUTER

SCIENCE

Bioinformatics: Theory & Applications 4

Machine Learning 3

Fundamentals of Python 3

Molecular Modeling 3

Molecular Biology 4

Discrete Models of Proteins 3

Complex Networks and Systems Biology 3

MATHEMATICS Real Analysis I 3

Differential Geometry 3

Graph Theory I 3

Graph Theory II 3

Complex Analysis 3

Modern Algebra I 3

ACADEMIC AWARDS

■ Full-time Graduate Research Assistantship Award, (2017 – 2021) NIH Program Project Grant AG012411-17A1 (WST Griffin, PI), University of Arkansas for Medical Sciences, Little Rock AR 72205, Arkansas, USA.

Full Tuition Scholarship with stipend

■ Full-time Graduate Research Assistantship Award, (2015 – 2016), Department of Information Science, University of Arkansas at Little Rock, Univ. of Arkansas for Medical Sciences and the Univ. of Arkansas at Little Rock, Joint PhD Program, Little Rock, Arkansas, USA Full Tuition Scholarship with stipend and partial health insurance support

■ Full-time Graduate Teaching Associate Award (2013-2015), Department of Mathematics & Statistics, East Tennessee State University, Tennessee, USA.

Full Tuition Scholarship with stipend

■ Faculty Award: Outstanding Graduate Student (2014 /2015), Department of Mathematics & Statistics, East Tennessee State University, Johnson City, Tennessee, USA For being the Outstanding Graduate Student for 2014/2015 academic year

■ R Programming by Johns Hopkins University on Coursera. Certificate earned on December 4, 2016.

■ Drug Discovery by University of California, San Diego on Coursera. Certificate earned on December 4, 2016.

■ The Data Scientist’s Toolbox by Johns Hopkins University on Coursera. Certificate earned on November 5, 2016.

UNIVERSITY TEACHING EXPERIENCE

Role: Instructor /Teaching Associate, Department of Mathematics and Statistics, East Tennessee State University, Johnson City, TN 37604, U.S.A

Details of Undergraduate Credits Taught

Year/Semester

(Jan 2014 –

May 2015)

Sections( Number

of classes taught)

Detail of Credits Taught Job Description

Spring

2014(Jan. –

May, 2014)

1 ( learning-support

class)

3 Credits (probability &

statistics)

5 hours of in-class

teaching every.

Additional 2 hours

weekly of office

hours was observed

Developed syllabi that clearly

outline the course requirements,

rationale, goals, and objectives

Submitted digital copies of syllabi

and course handouts to the Office

of Academic Affairs each semester

Selected textbooks and other

resources for the class

Prepared class sessions and

assignments to help students grasp

course content and how it

integrates with overall student

learning outcomes for the course

Taught courses according to the

PIU catalog descriptions and in

accordance with defined course

standards and outcomes

Created a learning environment

that encouraged student

involvement and participation

Documented students’ attendance,

participation, and academic

progress by giving and grading

assignments, projects, quizzes

and/or examinations that lead to a

final grade

Maintained posted office hours

Accessible to students outside the

classroom, providing ample

periods of time for counseling and

mentoring students in matters

related to academic success, life

goals and development

Use of instructional technology

(D2L, Drop box etc.)

Summer

2014(June –

Aug. 2014

1 ( learning-support

class)

3 Credits (probability &

statistics)

5 hours of in-

class teaching

every day of the

summer

Additional 3

hours weekly of

office hours was

observed

Fall 2014 (

Aug. –

Dec.2014)

2 (learning-support

class)

6 credits (probability &

statistics)

10 hours of in-

class teaching on

weekly basis

Additional 4 hours

of office hours

was observed

Spring

2014(Jan. –

May,2015)

2 (one learning-

support and one

regular class)

8 credits (probability &

statistics)

8 hours of in-class

teaching on

weekly basis

Additional 4 hours

of office hours

was observed

PUBLICATIONS: JOURNALS & THESIS

[1]. Samuel Kakraba, Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Narsimha Reddy Penthala, Liu Ling, Ramani Alla, Shoban Babu Bommangani, Steven Barger, W. Sue T. Griffin, Peter Crooks and, Robert Joseph Shmookler Reis, “ A Novel Drug that Binds GFAP and Tubulin Attenuates and Reverses Protein Aggregation Associated with Neurodegenerative Diseases.” Antioxidants & Redox Signaling, submitted Aug 30,2018

[2] Samuel Kakraba, Elaine Loudermilk, Sophia Liu, Zhanxin Sha, Liang Wang, Ke-Sheng Wang “Age difference in associations of alcohol consumption and skin allergy with nonmelanoma skin cancer in US adults”, Manuscript pending submission

[3]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J. Shmookler Reis, Srinivas Ayyadevara and Suresh K. Bowroju. “The Synthesis and Evaluation of TDZD analogs to delay, prevent, or reverse age- associated diseases”. U.S Patent Application pending submission

[4]. Ayyadevara, S., Balasubramaniam, M., Kakraba, S., Alla, R., Mehta, J. L., & Shmookler Reis, R. J. (2017). Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxidants & Redox Signaling, 27(17), 1383-1396. doi:10.1089/ars.2016.6978

[5]. S. Kakraba, and D. Knisley, “Graph-theoretic model of single point mutations in the cystic fibrosis transmembrane conductance regulator”. Journal of Advances in Biotechnology, vol. 6, no. 1, pp. 780–786, Jun 2016.

[6]. Kakraba,Samuel,”A Hierarchical Graph for Nucleotide Binding Domain 2”. Electronic Theses and Dissertations. Paper 2517. http://dc.etsu.edu/etd/2517 Digital Commons @ East Tennessee State University, East Tennessee State University, USA, May 2015

SELECTED CONFERENCE PRESENTATIONS

The following publications, patent and presentations were supported in part by NIH Program Project Grant AG012411-17A1 (WST Griffin, PI) and the Arkansas INBRE program -- supported by funding from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) (P20 GM103429)

(formerly P20 RR016460). Sponsorship included flight ticket, conference registration fees, hotel and meals and transportation where necessary.

[1]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “ Identifying Novel Drugs for Treatment of Neurodegenerative Diseases by Quantitative Structure - Activity Approach in Proceedings of National IDeA Symposium of Biomedical Research Excellence

(NISBRE), Washington DC, USA, Jun 2018.

[2]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, Srinivas Ayyadevara., Caesar M. Compadre. A poster presentation titled “using quantitative structure-activity relationships in drug discovery to identify potential drugs to treat neurodegenerative diseases” in Proceedings of the 14th Annual MCBIOS:XV, Midsouth Computational Conference, The Mill Conference Center at MSU, Starkville, MS, USA, March 29-31, 2018

[3]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Screening and Characterization of Drugs to Block Protein Aggregation in Neurodegenerative Diseases"” in Proceedings of the Southeast Regional IDeA Conference, West Virginia University, West Virginia, USA, Jun 2017.

[4]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Drugs to Block Protein Aggregation in Neurodegenerative Diseases” in Proceedings of the 2017 21st International C.elegans Conference, University of California, Los Angeles, California, USA, Jun 2017.

[5]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Drugs to Block Protein Aggregation in Neurodegenerative Diseases” in Proceedings of the 2017 Drug Discovery and Development Colloquium, University of Arkansas for Medical Sciences, Little Rock, USA, Jun 2017.

[6]. Suresh K. Bowroju, Meenakshisundaram Balasubramaniam, Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Design and Synthesis of Cyanoreseveratrol Aanalogs to Prevent and Treat Age-Related Sarcopenia” in Proceedings of the 2017 Drug Discovery and Development Colloquium, University of Arkansas for Medical Sciences, Little Rock, USA. Jun 2017

[7]. Suresh K. Bowroju, Narsimha R. Penthala, Samuel Kakraba, Peter A. Crooks, Srinivas Ayyadevara, and Robert J. Reis. A poster presentation titled “P16-Synthesis and Evaluation of Novel Drug Molecules to Prevent and Treat Age-related Sarcopenia” in Proceedings of the 2017 MALTO Program Schedule, The University of Louisiana Monroe, Monroe, LA 71209, USA. May 2017

[8]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. An oral presentation titled “Screening and Characterization of Small Molecules that Reduce Aβ142 Amyloid Aggregation In Nematode C.elegans” in Proceedings of the 14th Annual MCBIOS:XIV, Midsouth Computational Conference, Embassy Suites, Little Rock, Mar. 2017

[9]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Effects of Small Molecules on Protein Aggregation and Paralysis in C.elegans Expressing Aβ142 in muscle” in GPIS Biochemistry and Molecular Biology Track Poster Session, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA, Sep 2016.

[10]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Effects of Small Molecules on Protein Aggregation and Paralysis in C.elegans Expressing Aβ142 in the Muscle” in Proceedings of AR-BIC Second Annual Conference, Embassy Suites, Little Rock, Arkansas, USA, Apr 2016.

[11]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. An oral presentation titled “Effects of Small Molecules on Protein Aggregation and Paralysis in C.elegans expressing Aβ142 in the Muscle” in Proceedings of National IDeA Symposium of Biomedical Research Excellence (NISBRE), Washington DC, USA, Jun 2016.

[12]. Samuel Kakraba: Visiting Speaker for Undergraduate Research Project for Prof. Debra Knisley and Prof. Ariel Cintron-Arias 2015 Mathematical Association of America’s SUMMA Program—Strengthening Underrepresented Minorities in Mathematical Achievement funded by National Security Agency, East Tennessee State University, Johnson City, Tennessee, USA, Jun 2016.

[13]. Samuel Kakraba, Narsimha R. Penthala, Peter A. Crooks, Robert J.S Reis, and Srinivas Ayyadevara. A poster presentation titled “Effects of Small Molecules on Protein Aggregation and Paralysis in C.elegans Expressing Aβ142 in the Muscle” in Proceedings of the 13th Annual MCBIOS:XIII, Midsouth Computational Biology and Bioinformatics Society Conference, Memphis, Tennessee, USA, Mar 2016.

[14]. Samuel Kakraba, and Debra J. Knisley. An oral presentation titled “A Graph-theoretic Model of Nucleotide Binding Domain 2 of the Cystic Fibrosis Transmembrane Conductance Regulator” in Proceedings of the 13th Annual MCBIOS:XIII,Midsouth Computational Biology and Bioinformatics Society Conference, Memphis, Tennessee, USA, Mar 2016.

[15] Samuel Kakraba, and Debra J. Knisley. A poster presentation titled “A Graph-theoretic Model of Nucleotide Binding Domain 2 of the Cystic Fibrosis Transmembrane Conductance Regulator” in Proceedings of the 13th Annual MCBIOS:XII, Midsouth Computational Biology and Bioinformatics Society Conference, Marriott Hotel, Little Rock, Arkansas, USA, Mar 2015. Flight was sponsored by the department of mathematics and statistics of East Tennessee State University.

[16]. Samuel Kakraba, and K. Wang. An oral presentation titled “Association of Alcohol Consumption and Skin Allergy with Non-Melanoma Skin Cancer: Findings from the 2012 National Interview Health Survey” Conference, East Tennessee State University, Johnson City, Tennessee, USA, Apr 2015. PROFESSIONAL AFFILIATIONS & CAMPUS ACTIVITIES

[1]. Co-chair, Next Generation Sequence Section, 2016 Conference of Midsouth Computational Biology and Bioinformatics Society (MCBIOS), Memphis, Tennessee, USA. 2016

[2]. Member, Midsouth Computational Biology and Bioinformatics Society (MCBIOS), Arkansas, USA 2015– Present

[3]. Member, American Mathematical Society, Washington D.C, USA. 2014 –2015

[4]. Vice President, UALR/UAMS Bioinformatics Club, Little Rock, Arkansas, USA. 2016 –2017

[5]. Member, Kappa Mu Epsilon (KME) Tennessee Beta Chapter, National Mathematics Honor Society, Johnson City, Tennessee, USA. 2015

[6]. Member, Mathematics & Statistics Club, East Tennessee State University, Johnson City, Tennessee, USA. 2013 – 2015

[7]. Member, ETSU Abstract Algebra Club, East Tennessee State University, Johnson City, Tennessee, USA. 2014 – 2015

[8]. Founder and President, Wildlife Conservation Club, University Practice Senior High School, Cape Coast, Ghana. 2002 –2004

OTHER TEACHING EXPERIENCE

Department of Mathematics and Statistics, Wesley Girls’ High School, Cape Coast, Ghana. Course Instructor (Pure & Modern Mathematics) Jan 2011 – Jul 2013 Teaching several classes of students in Senior High School (11th and 12th grade) modern and pure mathematics.

Montessori Basic School, Pedu, Cape Coast, Ghana. Class Teacher (taught all primary school subjects for stage 1) --- Sept. 2007 – July 2007

Cherish International School, Pedu, Cape Coast, Ghana Class Teacher (taught all primary school subjects for stage 1) – Sept. 2004 – August 2006 CO-CURRICULAR AWARDS

First Place: Completed 5000 meters (5K) in 20.34.4 Sec in Boys’ Division of University Practice Senior High School, Cape Coast, Central Region, Ghana, 2001/02

Second Place: Completed 5000 meters (5K) in 17.41.55 Sec in Boys’ Division of University Practice Senior High School, Cape Coast, Central Region, Ghana, 2002

Third Place: Completed 5000 meters (5K) in 19.17.14 Sec in Boys’ Division of University Practice Senior High School, Cape Coast, Central Region, Ghana, 2003

First Place: Completed 1500 meters (1.5K) in 5:14:40 Sec in Boys’ Division of Cape Coast, Circuit 4, Basic Schools Sport Festival, Cape Coast, Central Region, Ghana, 1998

Third Place: Completed 3000 meters (3K) in 11.09.39 Sec in Boys’ Division of Cape Coast, Circuit 4, Basic Schools Sport Festival, Cape Coast, Central Region, Ghana, 1998 LANGUAGES

English: Official Language.

English: Fluent (speaking, reading, writing).

Fanti: Native Language.

Fanti: Fluent (speaking, reading, writing).

Twi: Fluent (speaking, reading, writing).

PROGRAMMING LANGUAGES/SKILLS/ OPERATING SYSTEMS/SOFTWARES

R-Statistical Software

Programming in Python

Programming in Perl

Bash Scripting, Graph Prism,

Minitab Statistical Software,

Linux

Windows

TEX

LATEX

Microsoft Office (Word, Excel, PowerPoint)

INTEREST

Sports and Reading

REFEREES

■ Prof. Robert J. Shmookler Reis

Senior Research Career Scientist,

Veterans Medical Center, and Udupa Chair of

Gerontologic Research,

Professor of Geriatrics, Biochemistry/Mol.Biol.,

and Pharmacology

University of Arkansas for Medical Sciences

629 Jack Stephens Drive,

Room 4120, Little Rock,

AR 72204, USA

Email: adx1uk@r.postjobfree.com

Tel: +1-501-***-****

■ Prof. Robert M Price Jr.

Chair and Professor

Department of Mathematics & Statistics

East Tennessee State University

P. O. Box 70663, Johnson City, TN 37614, USA

Email: adx1uk@r.postjobfree.com

Tel: +1-423-***-****

■ Prof. Robert B. Gardner

Professor and Graduate Coordinator (interim),

Department of Mathematics & Statistics

East Tennessee State University

P. O. Box 70663, Johnson City, TN 37614, USA

Email: adx1uk@r.postjobfree.com

Tel: +1-423-***-****

■ Prof. Debra J. Knisley

Professor and Director of the Institute for

Quantitative Biology,

Department of Mathematics &Statistics

East Tennessee State University

P. O. Box 70663, Johnson City,

TN 37614, USA

Email: adx1uk@r.postjobfree.com

Tel: +1-423-***-****

■ Jamie W. McGill

Assistant Professor

Department of Mathematics & Statistics

East Tennessee State University

P. O. Box 70663, Johnson City,

TN 37614, USA

Email: adx1uk@r.postjobfree.com

Tel: +1-423-***-****

■ Dr. Ernest Yankson

Senior Lecturer

Department of Mathematics & Statistics

University of Cape Coast

School of Physical Sciences,

University of Cape Coast,

Cape Coast, Ghana

Email: adx1uk@r.postjobfree.com

Tel: +2-332-***-*****

■ Prof. Jonathan Arko Fletcher

Professor and Dean,

School of Education & Leadership

University of Ghana, Legon

College of Education,

University of Ghana, Legon,

P.O. Box LG 1181, Ghana

Email: adx1uk@r.postjobfree.com

Tel: +2-332-***-*****

■ Dr. Samuel M. Naandam

Senior Lecturer

Department of Mathematics & Statistics,

University of Cape Coast

School of Physical Sciences,

University of Cape Coast,

Cape Coast, Ghana

Email: adx1uk@r.postjobfree.com

Tel: +2-332-***-*****

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