Bikramajit Singh Saroya

Phone: 1-869-***-****, Email: adpbqe@r.postjobfree.com Address- Bird Rock, Basseterre, St Kitts and Nevis Education Kasturba Medical College (KMC), Manipal University, Karnataka, India. 2005-2011 Bachelor of Medicine & Bachelor of Surgery (MBBS),

(KMC Manipal has been rated among the Top 10 Medical School in India for the last 10 yrs)

Work

2/2016 - present - Course Director Pathophysiology, Assistant Professor, Pathology and Biomedical Research, Editor-in-Chief, Windsor Insight, Faculty Adviser - American Medical Student Association (AMSA), Career Guidance Counselor, Windsor University SOM, St Kitts, WI

10/2015 - 2/2016 - Assistant Professor in Pathology, Editor-in-Chief “Windsor Insight” (University Medical Journal), Windsor University SOM, St Kitts, WI

8/2014 – 8/2015 – Clinical Tutor in Pathology, St George’s University, Grenada

12/2012 – 7/2014 – Clinical/Bench Research Associate, Penn State University Hershey Cancer Institute

7/2012 – 10/2012 - Resident Medical Officer, Department Of Medical Oncology at Max Super Specialty Hospital, Phase VI, Mohali, Punjab, India

9/2011- 11/2011 - House Surgeon, Department of Pediatrics at Government Medical Multispecialty Hospital, Sector 16, Chandigarh, India Certifications/Examinations s

Punjab Medical Council (India) Certified

USMLE Step 1, Step 2(CK and CS) Passed(1

st

Attempt)

ECFMG Certified

TOEFL 111/120

United States Clinical/Research Experience (> 2 years)

Clinical

9/2012 - 1/2013 Clinical Observership in Hematology/Oncology at Penn State Hershey Cancer Institute at Hershey, Pennsylvania

2/2012 - 6/2012 Clinical Observership in Hematology/Oncology at Barnes Jewish Hospital (Washington University School of Medicine) at St Louis, Missouri

1/2012 Clinical Observership in Internal Medicine at Sparrow Hospital (Michigan State University), Lansing, Michigan

2/2009 Clinical Clerkship in the General Surgery Service at the Tulane University Hospital and Clinic, New Orleans, Louisiana

1/2009 Clinical Clerkship in the Hematology/Oncology Service at the Louisiana State University Hospital, through a Visiting Student Program with Tulane University School Of Medicine, New Orleans, Louisiana

Research

12/2012 – 7/2014 Clinical Research Associate, Penn State University Hershey Cancer Institute

2/2013 – 3/2015 Co-investigator, Retrospective Study - Title - "Treatment of Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia and Relapsed B Cell Non-Hodgkin's Lymphoma patients with Vorinostat(SAHA), Cladribine and Rituximab(SCR) chemotherapy VS patients receiving standard chemotherapy regimens at Penn State University and OHSU Knight Cancer Institute". PI- Dr Elliot Epner, Penn State Hershey Cancer Institute, Hershey, Pennsylvania

1/2013 – 4/2015 Co-Investigator- Retrospective Study- Title –“Determine the safety of early discharge after AML induction chemotherapy.” PI - Dr David Claxton, Penn State Hershey Cancer Institute, Hershey, Pennsylvania

5/2013 – 12/2014 Co-Investigator- Retrospective Study – Title- “Determinants of Survival In Allogeneic Marrow and Stem Cell Transplant at Hershey Medical Center

(HMC).” PI- Dr David Claxton, Penn State Hershey Cancer Institute, Hershey, Pennsylvania

12/2012 - 1/2013-Clinical/Bench Research Associate - Colon Cancer Lab-Penn State Hershey Cancer Institute, Hershey, PA, Supervisor- Dr Wafik El-Deiry – Title-

“Association between apoptotic cells, debris and circulating tumor cells(CTCs) with response to therapy and survival in metastatic colorectal cancer patients”

10/2012 - 1/2013- Bench Research Scholar- Mantle Cell Lymphoma Lab- Penn State Hershey Cancer Institute, Hershey, PA. Supervisor- Dr Elliot Epner

2/2012 - 9/2012- Clinical Research Associate. Supervisor- Dr J. Subramanian- Siteman Cancer Center, Washington University School Of Medicine, St Louis, Missouri.

4/2012 – 9/2012- Clinical Research Associate. Supervisor- Dr A. Craig Lockhart- Siteman Cancer Center, Washington University School Of Medicine, St Louis, Missouri

9/2006 – Project Incharge of a Community Based Project “Is routine Growth Monitoring Effective? - An evaluation of growth monitoring camps in the field practice area of a teaching hospital” Supervisor- Dr Suma Nair, Department of Community Medicine, Manipal.

8/2006 - Project Incharge of a Community Diagnosis Study undertaken by house-to-house survey in the rural sector. It included interaction with member of the community through village meetings and group discussions, visits to health facilities to observe their functioning and holding health education sessions in the community. Supervisor- Dr Suma Nair, Department of Community Medicine, Manipal.

Peer Reviewed Publications/Current Projects

Epner EM, Saroya BS, Hasanali ZS, Loughran TP Jr. Combination epigenetics and immunotherapy overcomes resistance to monoclonal antibodies in hematological malignancies: A new therapeutic approach. Exp Hematol. 2016 Mar;44(3):157-60. doi: 10.1016/j.exphem.2015.12.011. Epub 2016 Jan 21.

Hasanali ZS, Saroya BS, Stuart A, Shimko S, Evans J, Vinod Shah M, Sharma K, Leshchenko VV, Parekh S, Loughran TP Jr, Epner EM. Epigenetic therapy overcomes treatment resistance in T-cell prolymphocytic leukemia. Sci Transl Med. 2015 Jun 24;7(293):293ra102. doi: 10.1126/scitranslmed.aaa507. PMID- 26109102 . Status - Published

Roberto A. Ferro, Mira Mitry, Zunjia Zhu, W. Christopher Ehmann, Witold Rybka, Kevin Rakszawski, Nicole Agositno, Bikramajit Singh Saroya, David F. Claxton, M.D. Early Discharge and Outpatient Management after AML Induction Chemotherapy. Journal of Clinical Oncology. Status – Submitted

Allen J.E., Saroya B.S., Kunkel M., Dicker D.T., Das A., Joudeh J., Peters K., Zhu J., El- Deiry W.S. Apoptotic CTCs and debris in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs. Oncotarget. 2013 Oct 17. Cited in PubMed PMID: 24334302; Publication Status: Published.

Saroya B.S., Hasanali Z.S., Sharma K., Epner E.M. (2013). Vorinostat In The Treatment Of Malignant Lymphoma. In Owen A. O’Connor(Ed.), Novel Targeted Drugs for the Treatment of Lymphoma (pp. 647-668). Astoria, NY: Springer Clinical Medicine.

Desai M.D., Saroya B.S., Lockhart A.C. Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers. Expert Opin Investig Drugs. 2013 Mar; 2013 Mar;22(3)(1354-3784): 341-356. Cited in PubMed; PMID: 23316969. Publication Status:Published.

Sorscher S.M., Saroya B.S. A molecularly confirmed neuroendocrine tumor resulting from Lynch Syndrome. Journal of Gastrointestinal Oncology. 2013 Mar; DOI: 10.3978(2078- 6891): 95-96. Cited in PubMed; PMID: 23451331. Publication Status: Published.

Subramanian J, Nagaraj G, Rogenbogen T, Saroya B.S, Lane A- Status Report for Clinical Trials from ClinicalTrials.gov website - Review of Ongoing Clinical Trials in Non-Small Cell Lung Cancer-Journal of Thoracic Oncology Submitted – September 2013

Lamparella N.E., Saroya B.S., Yang Z., Sarwani N.E., El-Deiry W.S. Contradictory KRAS mutation test results in a patient with metastatic colon cancer: A clinical dilemma in the era of personalized medicine. Cancer Biol Ther. 2013 Jun; 14(8): 699-702. Cited in PubMed; PMID: 23792572. Publication Status: Published.

Al-Marrawi M.Y., Saroya B.S., Brennan M.C., Yang Z., Dykes T.M., El-Deiry W.S. Off- label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer. Cancer Biol Ther. 2013 Jun; 14(8): 703-710. Cited in PubMed; PMID: 23792568. Publication Status: Published.

Saroya B.S., Sharma K., Epner E.M. Epigenetic Combination - Vorinostat(SAHA), Cladribine and Rituximab(SCR) in the treatment of Follicular Lymphoma. Publication Status: Under Review.

Medical School Honors /Awards

2005-07-Certificate of Appreciation Awarded by Blood Bank, Kasturba Hospital for organizing Blood Donation Camps

2006 Certificate of Merit Awarded by Department of Community Medicine for organizing national Filaria Control Program

2006-Certificate of Appreciation Awarded by Department of Community Medicine for organizing Pulse Polio Drive

2007-09-Gold Medal for placing 1st in Kho-Kho and Kabaddi (2yrs champions) and Silver Medal for placing 2nd in field Hockey at Annual Inter-Batch Sports/Culturals Meet. Other Awards/Accomplishments

July 2005 - Selected for MBBS at KMC, Manipal. (All India rank - 782 among 255,000 Students appearing in the entrance exam) (Top 0.5 % of the nation)

May 2005 - All India Senior Secondary Certificate Examination (Equivalent to Senior College)in Subjects of Biology, Physics, Chemistry, English Core, French, Work Experience, Physical and Health Education and General Studies with an aggregate of 85.6% (top 1% of the nation)

2004 - Sportsperson of the Year awarded by the Chandigarh Sports Association.

May - 2003 All India Secondary School Examination (Equivalent to Freshman College) in subjects of Science, Mathematics, English Course A, Social Studies and Hindi with an aggregate of 91.2%

(top 1% of the nation).

2002-Represented India at the 30th ASIAN SCHOOLS FOOTBALL CHAMPIONSHIP held at Singapore.

2002-03 - Captain St John's High School soccer team which placed 1st at the Edmund Rice Sports Meet and 2nd at the State School Football Tournament and the Inter School Football Tournament organized by the Education Department of Chandigarh.

2010 - Member of the SECOND placed college "Bhangra" team - a folk dance from Punjab, India (performed in front of 5000 spectators at college festival-"FLAVA").

Black Belt - Taekwondo (Korean Martial Art) under Master Rhyon Suraj - The Kings Academy of Martial Arts, Chandigarh.

Language Fluency

English (Native/functionally native)

French (Advanced)

Hindi (Native/functionally native)

Punjabi (Native/functionally native)

Kannada (Good)

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