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Stephanie Santos

Senior Clinical Laboratory Scientist

ad4ywr@r.postjobfree.com • 510-***-****

South San Francisco, CA, 94080

Detail-oriented scientist with extensive experience in molecular biology, genetic analysis, and advanced clinical laboratory techniques to elevate healthcare standards. Skilled in data analysis, test result release, and bioinformatics tools for viral genome assessment. Recognized for technical expertise and collaborative leadership, training analysts and driving transitions. Effective communicator and problem solver, translating complex processes and providing innovative solutions. Seasoned in optimizing workflow, training and mentoring junior staff, and implementing cutting-edge technologies to enhance diagnostic capabilities. Accomplished trainer, driven by passion for continuous learning, extensive management experience, and strong technical skills across diverse domains. Proficient in a wide range of laboratory techniques and instrumentation, ensuring strict adherence to quality control and regulatory standards. Proficiencies

Molecular Biology & Genomics: Genotypic Data Analysis, Next Generation Sequencing, DNA extraction, Sanger Quality Assurance & Standard Procedures: Standard Operating Procedures, Validation Testing, SNP Assay Techniques & Problem Solving: RT-PCR, InDels, Problem Solver, Digestion-Ligation, Bacterial Transformation Laboratory Operations & Training: Plasmid Prep, Hospital Lab/Clinical Reference Labs, RNA isolation Career Experience

Sapphiros Labs, Redwood City, CA 2022 – 2023

General Lab Supervisor/Clinical Lab Scientist II

Utilize molecular biology techniques, encompassing DNA extraction, PCR amplification, and genotyping for genetic analysis. Enforce laboratory quality standards and protocols by reporting any deviations to laboratory manager and collaborating with quality manager to ensure documentation completion. Execute analysis, review, and timely release of test results, according to establish turnaround times. Adhere to laboratory safety protocols and procedures with excellent attention to detail and accuracy in experimental procedures. Implement quality control/assurance procedures by showcasing robust organizational and time management prowess.

• Engaged in testing and maintained consistency in sample testing alongside patient specimens, while participating in regulatory inspections.

• Oversaw accurate labeling of reagents and test kits, including recording dates of receipt, expiration, and opening, while adhering to vendor-prescribed storage protocols.

• Managed COVID-19 and SNP assay preparation from design to execution, including TaqMan assay optimization, while contributing to validation and verification efforts.

• Involved in assay development by actively participating in validation and verification processes. P a g e 2 2

MONOGRAM BIOSCIENCES, INC., South San Francisco, CA 2002 – 2021 Senior Clinical Laboratory Scientist

Leveraged NGS and Sanger platforms to analyze HIV and HCV genotypic data, as well as assess phenotypic-genotypic discordance, in commercial and pharmaceutical samples. Supported CQM by conducting data analysis, reviewing, and reporting on Proficiency Testing samples across accreditation agencies. Collaborated with IT department for assay validation and supports Clinical Project Managers in meeting client-driven delivery deadlines. Applied molecular biology techniques, such as PCR, cloning, and gene expression analysis. Experienced in utilizing bioinformatics tools (BLAST, Geneseq Pipeline, Sequencher) and molecular techniques (PCR, qPCR, cloning, Sanger sequencing) to detect HIV-1 and HCV genomes, as well as proficient in preparing DNA libraries for NGS on Illumina platforms.

• Participated in validation testing, SOP documentation, and collaborative QA efforts.

• Deployed bioinformatics tools for genesequencing analysis, encompassing viral genome assembly, drug resistance assessment, and subtyping analysis.

Trained Geneseq data analysts and led transition from Sanger to NGS data analysis.

• Partnered with Medical Science Liaisons to convey essential information and discoveries to healthcare professionals. Additional Experience

Clinical Lab Scientist Stanford Health Systems, Pleasanton, CA Medical Technologist - Auto Chemistry Department Smith-Kline Beecham Clinical Laboratories, Dublin, CA Education

Bachelor of Science in Medical Technology De OCAMPO Memorial College, Manila, Philippines Certification

Licensed Certification Clinical Laboratory Scientist - Generalist, CA (MTA 36906)