R E S U M E

MATT CONOVER

CONTACT INFORMATION

acui3q@r.postjobfree.com

314-***-****

EDUCATION

****- ****

Wake Forest University, Winston-Salem, NC

§ Ph.D. Molecular Genetics-Microbiology

****-****

Campbell University, Buies Creek, NC

§ B.S. Biochemistry and Biology

EMPLOYMENT

2011-present

Research Scientist/Postdoctoral Fellow

§ Washington University in St. Louis

§ Bench scientist and analyst

2014-present

Biotechnology Consultant

§ The BALSA Group

§ Product development and marketing

o Insecticide development

o Thrombophilia testing

o Agricultural yield improving systems

LEADERSHIP EXPERIENCE

n Team Lead biotech consulting

n Mentoring and Training, 10 graduate and

undergraduate students

n Teaching Assistant- 4 semesters

RESEARCH SKILLS

§ Molecular Techniques- cloning, SDS-PAGE, qPCR, protein purification, footprints, EMSAs, biofilm assays, RNA extraction, cDNA synthesis, ELISAs, microarrays, BioPlex, antibody tittering, tissue culture, attachment assays

§ Microscopy- confocal, fluorescent, scanning electron, standard light microscopy, cytospin analysis

§ Animal models- urethral and intranasal inoculation, model development, vaccination, tissue tittering, bronchial alveolar lavage

§ Software- MS Office, Prism, Pymol, SoftMax Pro, Zen AWARDS AND FUNDING

§ F32 funding through NIDDK

§ W.M. Keck Fellowship

§ Molecular Microbiology training grant (NIH T32), Washington University

§ Microbiology and Immunology training grant (NIH T32), Wake Forest University

§ Excellence in Biochemistry Award, Campbell University

§ Sigma Xi grant for undergraduate research

SCIENTIFIC EXPERIENCE

n 5 years of laboratory experience investigating the pathogenesis of E.coli as it relates to urinary tract infections (5 publications).

n 5 years of graduate research involving the pulmonary pathogenesis of Bordetella species and whooping cough (8 publications).

n Thoroughly trained independent researcher capable of analyzing and leading complex projects n Experience with assay development, following and writing SOP, record keeping, BSL-2 protocols PUBLICATIONS

§ Conover MS, Hadjifrangiskou M, Palermo J, Hibbing ME, Dodson K, and Hultgren SJ. Metabolic requirements of E.coli in intracellular bacterial communities during UTI pathogenesis. Mbio, In press, 2016.

§ Conover MS, Flores-Mireles AL, Hibbing ME, Dodson K, and Hultgren SJ. Establishment and Characterization of UTI and CAUTI in a Mouse Model. Journal of Visualized Experiments. 2015 Jun 23;(100):e52892. doi: 10.3791/52892.

§ Hibbing ME, Conover MS, and Hultgren SJ. The unexplored relationship between urinary tract infections and the autonomic nervous system. Autonomic Neuroscience. 2015 Jun 6. pii: S1566- 0702(15)30003-5. doi: 10.1016.

§ Schwartz DJ, Conover MS, Hannan TJ, Hultgren SJ. Uropathogenic Escherichia coli Superinfection Enhances the Severity of Mouse Bladder Infection. Monack DM, ed. PLoS Pathogens 2015;11(1):e1004599. doi:10.1371/journal.ppat.1004599.

§ Greene, S,. Pinkner, J., Chorell, E., Dodson, K. W., Shaffer, C. L., Conover, M. S., … Hultgren, S. J. (2014). Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli. mBio, 5(6), e02038–14. doi:10.1128/mBio.02038-14

§ Sukumar N, Nicholson TL, Conover MS, Ganguly T, Deora R. Comparative Analyses of a Cystic Fibrosis Isolate of Bordetella bronchiseptica Reveal Differences in Important Pathogenic Phenotypes. Bäumler AJ, ed. Infection and Immunity 2014;82(4):1627-1637. doi:10.1128/IAI.01453-13.

§ Nicholson, T.L., Conover, M.S., Deora, R. Transcriptome Profiling Reveals Stage- Specific Production and Requirement of Flagella during Biofilm Development in Bordetella bronchiseptica. PLoS ONE 7(11): e49166. doi:10.1371/journal.pone.0049166

§ Conover, M.S., Sukumar, N., Sloan, G., Mishra, M., Deora, R. The protein BpsR functions as a negative transcriptional regulator of Bps polysaccharide expression in Bordetella bronchiseptica. J. Bacteriol. 2012, 194(2):233-242.

§ Serra, D.O., Conover, M.S., Arnal, L., Sloan, G. P., Rodriguez, M. E., Yantorno O. M., Deora, R. Filamentous hemagglutinin-mediated cell-substrate and cell-cell adhesions are critical for Bordetella pertussis biofilm formation on abiotic surfaces and in the mouse nose and trachea. PLoS One 6(12): doi:10.1371/journal.pone.0028811

§ Conover, M.S ., Mishra, M ., Deora, R. Extracellular DNA is essential for maintaining Bordetella biofilm integrity on abiotic surfaces and in the mouse respiratory tract. PLoS One 6(2): doi:10.1371/journal.pone.0016861

§ Conover, M. S., Sloan, G. P., Love, C. F., Sukumar, N. Deora, R. The Bps polysaccharide of Bordetella pertussis promotes colonization and biofilm formation in the nose by functioning as an adhesin. Mol. Micro. (2010) 77(6), 1439–1455.

§ Sukumar, N., Sloan, G. P., Conover, M. S., Love, C. F., Mattoo, S., Kock, N. D. & Deora, R. 2010. Cross-species protection mediated by a Bordetella bronchiseptica strain lacking antigenic homologs present in acellular pertussis vaccines. Infect Immun 78: 2008-16.

§ Ma, L., Conover, M., Lu, H., Parsek, M.R., Bayles, K., Wozniak, D. 2009. Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix. PLoS Pathog 5(3): e1000354. doi:10.1371/journal.ppat.1000354

§ Sukumar, N., Love, C., Conover, M. S., Kock, N., Dubey, P., Deora, R. 2009. Active and passive immunizations with Bordetella colonization factor a protect mice against respiratory challenge with Bordetella bronchiseptica. Infect Immun, 77(2): p. 885-95.

Contact this candidate