Scott R. Hyde, Ph.D.

*** *. ***** ■ Jenks, Oklahoma 74037 ■ 918-***-**** ■ acs9on@r.postjobfree.com

Addendum

UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER

Doctor of Philosophy (Major – Microbiology & Immunology; Minor – Pathology)

Dissertation: The Effects of Aging on TNF-Glucocorticoid Interaction in Mice

Subjected to the Cecal Ligation and Puncture Model of Sepsis.

Dissertation Associated Publications

1. Hyde SR, McCallum RE and Stith R: Mortality and Bacteriology of Sepsis following Cecal Ligation and Puncture. Infection and Immunity 1990; 55:619-624.

2. McCallum RE, Llyod SS and Hyde SR: Enhanced TNF Response in Endotoxic Mice after Treatment with the Glucocorticoid Antagonist RU 486. In; Cellular and Molecular Aspects of Endotoxin Reactions, Edited Nowotny A, Spritzer JJ and Ziegler EJ. Elsevier Science Publishers B.V. 1990.

3. Hyde SR and McCallum RE: Lipopolysaccharide-Tumor Necrosis Factor-Glucocorticoid Interactions During Cecal Ligation and Puncture-Induced Sepsis in Mature Versus Senescent Mice. Infection and Immunity 1992; 60:976-982.

Master of Science, Microbiology & Immunology Master of Science, Pathology

Thesis: Histologic Identification of Selected Anaerobes in Acute

Intra-amniotic Infections and Maternal Recurrent Reproductive Failure.

Thesis Associated Publications

1. Altshuler G and Hyde SR: Fusobacterium: An Important Cause of Chorioamnionitis. Archives of Pathology and Laboratory Med 1985;109:739-743.

2. Altshuler G and Hyde SR: Clinicopathologic Considerations of Fusobacterium Chorioamnionitis. Acta Obstetrica Scandinavia 1988; 67:513-517.

NIH Research Grants & Contracts

National Institute of Aging (NIH); Principle Investigator, Pre-doctoral Research Grant, (1987-1990).

Invited Journal Reviewer

Pediatric and Developmental Pathology (1999 – Present)

Modern Pathology (1999-2002)

NIH Workshops & Presentations

Vaginal Infections and Prematurity Project: National Institute of Child Health and Human Development. (Epidemiological Branch) September 19-20, 1988.

Altshuler G and Hyde SR: An In Vitro Model of Umbilical Cord Vasospasm and Fetal Cerebral Hypoxia. NIH Workshop on the Role of Infection in Precipitating Preterm Labor, National Institutes of Health, September 19, 1988.

Hyde SR and Altshuler G: Histologic Identification of Perinatal Pathogens from Formalin Fixed Paraffin Embedded tissues related to Acute Intra-amniotic infections. NIH Workshop on the Role of Infection in Precipitating Preterm Labor, National Institutes of Health, September 20, 1988.

Hyde SR and Altshuler G: Immunofluorescent Labeling of Anaerobic Bacteria in Chorioamnionitis. NIH Workshop on the Role of Infection in Precipitating Preterm Labor, National Institutes of Health, September 20, 1988.

Bibliography

ORIGINAL PAPERS: (Listed most recent first)

17. Terry J, Pluchotta FR, Sanders SP:, Vergilio J, Hyde SR and Boyd T: Congenital Multisystem Langerhans Cell Histiocytosis with Placental Involvement. Pediatric and Developmental Pathology 2013 May-June;16 (3):224-8.

16. Myerson D, Parkin R, Benirschke K, Tschetter C and Hyde SR: The Pathogenesis of Villitis of Unknown Etiology: Analysis with a new conjoint immunohistochemistry-In situ hybridization procedure to identify specific maternal and fetal Cells. Pediatric and Developmental Pathology 2006; 9,(4): 257-265. * (Issue’s lead article and Journal cover artwork)*

15. Redline R, Boyd T, Campbell V, Hyde SR, Kaplan C, Khong TY, Prashner H, and Waters BL.: Society for Pediatric Pathology. Perinatal Section: Maternal Vascular Underperfusion Nosology Committee. Maternal Vascular Underperfusion: Reproducibility of placental reaction patterns. Pediatric and Developmental Pathology 2004; 17,(3): 237-249.

14. Procop GW, Jessen R, Hyde SR and Scheck DN.: Persistence of Plasmodium falciparum in the placenta after apparently effective quinidine/clindamycin therapy. Journal of Perinatology 2001; 21,(2):128-130.

13. Beebe LA, Cowan LD, Hyde SR and Altshuler G.: Methods to improve the reliability of histopathological diagnoses in the placenta. Paediatric and Perinatal Epidemiology 2000; 14,(2):172-178. * Investigation, Beebe LA. PhD Dissertation *

12. Hyde SR and Benirschke K.: Gestational Psittacosis: Report of a case with literature review. Modern Pathology 1997; 6,(10): 602-607. *Article reprinted in toto as a Mini Review in Infectious Diseases in Clinical Practice 1999; 6:519-524.*

11. Pickens J. Toubas P. Hyde SR and Altshuler G.: In Vitro Model of Human Venous Perfusion to Study the Effects of Meconium Staining of the Umbilical Cord. Biology of the Neonate 1995; 67:100-108.

10. Altshuler G and Hyde SR: A Bi-Discoid Monochorionic Placenta. Journal of Perinatology 1993; 8:492-493.

9. Hyde SR and Giacoia G: Congenital Herpes Infection: Placental and Umbilical Cord Findings. Obstetrics and Gynecology 1993; 81: 852-855

8. Hyde SR and McCallum RE: Lipopolysaccharide-Tumor Necrosis Factor-Glucocorticoid Interactions During Cecal Ligation and Puncture-Induced Sepsis in Mature Versus Senescent Mice. Infection and Immunity 1992; 60:976-982.

7. McCallum RE, Llyod SS and Hyde SR: Enhanced TNF Response in Endotoxic Mice after Treatment with the Glucocorticoid Antagonist RU 486. In; Cellular and Molecular Aspects of Endotoxin Reactions, Edited Nowotny A, Spritzer JJ and Ziegler EJ. Elsevier Science Publishers B.V. 1990.

6. Hyde SR, McCallum RE and Stith R: Mortality and Bacteriology of Sepsis following Cecal Ligation and Puncture. Infection and Immunity 1990; 55:619-624.

4. Hyde SR, Smotherman J, Moore J and Altshuler G: A Model of Bacterially-Induced Umbilical Vein Spasm, Relevant to Fetal Hypoperfusion. Obstetrics and Gynecology 1989; 73:966-969.

5. Altshuler G and Hyde SR: Meconium Induced Vasocontraction: A Potential Cause of Hypoperfusion and Poor Perinatal Outcome. Journal of Childhood Neurology 1988; 4:137-142.

3. Altshuler G and Hyde SR: Clinicopathologic Considerations of Fusobacterium Chorioamnionitis. Acta Obstetrica Scandinavia 1988; 67:513-517. * Article abstracted in the 1990 Year Book of Perinatal and Neonatal Medicine.*

2. Altshuler G, Jordan J and Hyde SR: Amniotic Squamous Balls: Associations with Oligohydramnios, Amnion Nodosum, Potter's Syndrome and Lung Hypoplasia. Archives of Gynecology 1988.

1. Altshuler G and Hyde SR: Fusobacterium: An Important Cause of Chorioamnionitis. Archives of Pathology and Laboratory Med 1985;109:739-743. * Article abstracted in the Year Book of Pathology and Clinical Pathology, 1987.*

BOOK CHAPTERS

1. Altshuler G and Hyde SR: Clinicopathologic Implications of Placental Pathology. Clinical Obstetrics and Gynecology. Vol 39, No. 3. In; RM Pitkin and JR Scott (eds), Lippincott-Raven, Philadelphia, 1996.

2. Hyde SR and Altshuler G: Placentitis. Pathology of Infectious Disease. In; FW Chandler and DH Connor (eds). Appleton and Lange, Connecticut, 1997. Awarded ”Medical Text Book of the Year, 1997” ; Doody Professional Rating Service. Awarded “ Best Medical and Basic Science Text Book of 1998” By the British Medical Society.

3. Hyde SR and Altshuler G: Infectious Disorders of the Placenta. Pathology of the Placenta. Contemporary Issues in Surgical Pathology, Vol 5, Eugene Perrin and Steve Lewis (eds) Churchill Livingstone, New York, 1999.

SELECTED ABSTRACTS ( Listed most recent first)

16. Justice PL, Johnson JR, Kaul A and Hyde SR: Adenovirus in Pregnancy: A case of fulminant maternal adenovirus hepatitis. Research in Osteopathic Graduate Medical Education, 2nd Annual Poster Symposium. Oklahoma City, Oklahoma May 6, 2010. * Awarded 1st Place and Oral Presentation*

15. Redline R, Boyd T, Campbell V, Hyde SR, Kaplan C, Khong TY, Prashner H, and Waters BL.: Maternal Vascular Underperfusion and Reproducibility of Placental Reaction Patterns. Pediatric and Developmental Pathology 2004; 17;7(1).

14. Redline R, Boyd T, Campbell V, Hyde SR, Kaplan C, Khong TY, Prashner H, and Waters BL.: Maternal Vascular Underperfusion: Reproducibility of Placental Reaction Patterns. Perinatal Section Nosology Committee. Annual Perinatal Symposium, Society for Pediatric Pathology. Cincinnati, Ohio. October 19, 2003.

13. Hyde SR, Glover S, Boykin R, Hyde RM and Rusch V: Enterococcus faecalis Induced Protection from Experimental Sepsis. Missouri Valley Branch; American Society for Microbiology. Omaha, Nebraska. March 15, 1991.

12. Hyde SR, Glover S, Boykin R, Hyde RM and Rusch: The Effect of Oral Treatment with Enterococcus faecalis on Cecal Ligation and Puncture-Induced Sepsis. Annual Meeting of the American Society for Microbiology. Dallas, Texas. May 7, 1991.

11. McCallum RE and Hyde SR: LPS-TNF-Glucocorticoid Interactions During CLP-induced Sepsis in Mature vs. Senescent Mice. 28th Annual Meeting of the Society for Leukocyte Biology. Aspen, Colorado. September 28, 1991.

10. Hyde SR and McCallum RE: Altered Glucocorticoid Regulation of the TNF Response in Aged Septic Mice. Missouri Valley Branch of the American Society for Microbiology. Kansas City, Missouri. April 10, 1990.

9. Hyde SR and McCallum RE: TNF-Glucocorticoid Interactions in Aged Septic Mice. The First Congress of the International Endotoxin Society. San Diego, California. May 10, 1990.

8. Hyde SR and McCallum RE: A Murine Model of Sepsis in the Aged. Annual Meeting of the American Society for Microbiology. New Orleans, Louisiana. May 15, 1989.

7. Hyde SR and Altshuler G: Fusobacterium Chorioamnionitis: An Important Infectious Cause of Human Preterm Labor. Graduate Education Day, University of Oklahoma Health sciences Center. Oklahoma City, Oklahoma. October 20, 1986.

6. Hyde SR and Altshuler G: An Investigation of Recurrent Reproductive Failure and Fusobacterium Chorioamnionitis. Pathology Day, University of Oklahoma Health Sciences Center. Oklahoma City, Oklahoma. April 26, 1986.

5. Altshuler G, Jordan J and Hyde SR: Pathogenic Considerations in a Microcomputer Study of 158 Clinical, Placental, and Autopsy Findings of 100 Neonates. Proceedings of the Sixth Annual Meeting of the Society of Perinatal Obstetricians, San Antonio, Texas, 1986.

4. Altshuler G and Hyde SR: Diffuse Placental Villous Dysmaturity: A frequent Sign of Major Congenital Anomalies. Interim meeting, Society for Pediatric Pathology. Cleveland, Ohio. Pediatric Pathology 1986; 5(1):88.

3. Altshuler G and Hyde SR: Fusobacterium Chorioamnionitis: Human and Murine Evidence of an Important Cause of Prematurity. Laboratory Investigation 1985:52;2.

2. Altshuler G and Hyde SR: Chorangiosis: Definition and Possible Significance. Pediatric Pathology 1984; 2(4):493.

1. Altshuler G and Hyde SR: Chorangiosis Revisited. Interim Meeting, Society for Pediatric Pathology, Cincinnati, Ohio, 1983.

THE SOCIETY FOR PEDIATRIC PATHOLOGY SLIDE SURVEY; 2010

1. Congenital Hydrops: Parvovirus, Case Report with Literature Review.

2. Sequential Immunosuppression following Bone Marrow Transplantation: A case report of Adenovirus Hepatitis.

THE SOCIETY FOR PEDIATRIC PATHOLOGY SLIDE SURVEY; 2011

1. Congenital Langerhans Cell Histiocytosis: Placental Involvement in Letterer-Siwe Disease.

2. Congenital Toxoplasmosis: Ingestion of a Raw Meat Salad, Laotian Larb. A case report and correlations between a large serological survey of Toxoplasmosis and prevalence of an infectious disease linked to a specific food.

THE SOCIETY FOR PEDIATRIC PATHOLOGY SLIDE SURVEY: 2012

1. Congenital Herpes simplex placentitis: Unique pathogenesis of a common but devastating ToRCHS infection.

2. Fusobacterium nucleatum chorioamnionitis: An important infectious cause of preterm delivery.

LETTERS TO THE EDITOR:

Hyde SR and Altshuler G: Need for Placental and Experimental Pathology to Determine Pathogenic Influences of Chronically Present Intra-amniotic Meconium. 1996. American Journal of Obstetrics and Gynecology. 174(5):1669-1670.

SELECTED INVITED LECTURES: (Listed most recent first)

9. Hyde SR: Placental Examinations; Impact on Malpractice Litigation. New Horizons In Perinatology: Toward the year 2000. Tulsa, Oklahoma. November 5, 1999.

8. Hyde SR: What in the World Went Wrong ? Subclinical Maternal Diseases, Placental Findings and Neonatal Outcome. New Horizons in Perinatal and Neonatal Care. Neonatal and Pediatric Nursing Symposium. Tulsa, Oklahoma. May 13, 1999.

7. Hyde SR: Placental Pathology 101. Care of Infants & Children: Neonatal and Pediatric Nursing Symposium. Tulsa, Oklahoma. March 19, 1998.

6. Hyde SR: Mechanisms of Intrauterine Fetal Demise. Children's Medical Center. Tulsa, Oklahoma. December 3, 1997.

5. Hyde SR: The Placenta: A Diary Of Gestational Life. Association of Women's Health. Obstetric and Neonatal Nurses Conference. Tulsa, Oklahoma. April 30, 1993.

4. Hyde SR: Children with Strokes: Fetus and Newborns. Pediatric Grand Rounds. Children's Medical Center. Tulsa, Oklahoma. May 4, 1993.

3. Hyde SR: Bacteriology and Mortality of Sepsis in Aged Mice. Oklahoma Medical Research Foundation, February 1, 1990.

2. Hyde SR and Altshuler G: Immunofluorescent Labeling of Anaerobic Bacteria in Chorioamnionitis. NIH Workshop on the Role of Infection in Precipitating Preterm Labor, National Institutes of Health, September 20, 1988.

1. Altshuler G and Hyde SR: An In Vitro Model of Umbilical Cord Vasospasm and Fetal Cerebral Hypoxia. NIH Workshop on the Role of Infection in Precipitating Preterm Labor, National Institutes of Health, September 19, 1988.

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