Frankie Costanza Ph.D.

***** *** *** *** *** Tampa Florida 33647

(718) 640 – 5510 acrhe8@r.postjobfree.com

*Willing to relocate

Executive Summary .

Diligent organic chemist with 6 years pre-clinical experience developing and preforming experiments with a focus on biocompatible drug delivery polymer systems in solid tumor indications in vivo as well as for antibacterial applications

Precise project management skills attained by simultaneously leading several undergraduate researchers on multiple projects with efficient time management

Ability to analyze and interpret large sets of data across multiple projects

Strong interpersonal skills developed as acting laboratory liaison with department faculty, students, and visitors regarding administrative affairs

Effective communicator and educator amongst hundreds of students annually in a lecture format by presenting complex scientific concepts in a simple coherent manner Education .

Ph.D. Organic/Medicinal Chemistry 2015

University of South Florida

Principle Investigator: Dr. Jianfeng Cai

B.S. Chemistry, cum laude 2009

Wagner College

Research Experience .

Extensive practical experience in multi-step synthesis, purification and characterization of small molecules of biological interest

Extensive experience in polymer synthesis, purification and characterization

Experience in solid phase synthesis of bioactive peptides and peptidomimetics

Formulation of biopolymer nanomicelles for in vivo applications such as novel anti- bacterials and as a drug delivery vesicle for novel therapeutic drugs

Design and synthesis of biodegradable polymer antibiotics

Familiar with a wide array of instrumental analysis tools such as a scanning electron microscope, atomic force microscope, fluorescence microscopy, solid phase peptide synthesis, MALDI-TOF, HPLC, LCMS, DLS, GPC, UV-vis, IR and NMR

Responsible for proof reading research proposals for our research group Posters and Presentations .

Chemistry Colloquium Oral Presentation April 2014 University of South Florida

American Chemical Society Poster Presentation March 2014 Dallas, Texas

Castle Conference Poster Presentation April 2013 University of South Florida

Teaching Experience .

Organic Chemistry 1&2 Discussion 2011-2015

o Conduct lectures relating to all current course material in multiple classes with

>100 students per semester. Prepare problems for students and guide them through problem solving exercises. Also responsible for making in class quizzes and exam grading

Organic Chemistry 1&2 Laboratory 2010-2011

o Guide students on how to properly and safely conduct organic chemistry experiments and interpret results. Also responsible for grading all lab material

General Chemistry 1&2 Laboratory 2009-2010

o Motivate students in learning about various new chemistry techniques and assist them in safely completing lab experiments. Also responsible for grading all lab material

Mentored 7 undergraduate students in the research lab as well as 1 new graduate student o Train students to properly run organic reactions in the lab Other Experience and Volunteer Work .

REU student in Dr. Miller’s lab Summer 2008

University of Florida

Ongata Rongai Village, humanitarian efforts Winter 2008 Kenya

Bobbi and the Strays Animal Shelter Summer: 2004, 2005, 2006, 2007 Manager of animal living conditions

Building 182, JFK Airport

Interests .

Biotechnology Market, Science Literature, Reading, Music, Softball (member of the USF Chemistry intramural team for 6 seasons), Outdoor Activities, Tennis, Traveling Publications (1 equal contribution) .

6. Yan Wang1, Frankie Costanza1, Haifan Wu, Daqian Song, Jianfeng Cai* and Qi Li*. PEG- poly (amino acid)s-encapsulated Tanshinone IIA as potential therapeutics for the treatment of hepatoma. J. Mat. Chem. B. 2014, 2 (20), 3115-3122. 5. Yan Wang, Daqian Song, Frankie Costanza, Huirong Zhu, Zhongze Fan,* Jianfeng Cai* and Qi Li.* Targeted Delivery of Tanshinone IIA-conjugated mPEG-PLGA-PLL-cRGD Nanoparticles to Hepatocellular Carcinoma. J. Biomed. Nanotechnol. 2014, 10, 3244-3252. 4. Frankie Costanza, Shruti Padhee, Haifan Wu, Yan Wang, Jesse Revenis, Chuanhai Cao, Qi Li* and Jianfeng Cai.* Investigation of antimicrobial PEG-poly(amino acid)s. RSC Advances, 2014, 4, 2089-2095.

3. Youhong Niu, Haifan Wu, Rongfu Huang, Qiao Qiao, Frankie Costanza, Xi-Sen Wang, Yaogang Hu, Mohamad Nassir Amin, Anh-My Nguyen, James Zhang, Edward Haller, Shengqian Ma, Xiao Li, and Jianfeng Cai*. Nanorods formed from a new class of peptidomimetics. Macromolecules, 2012, 45, 7350-7355. 2. Rongsheng E. Wang*, Frankie Costanza, Youhong Niu, Haifan Wu, Yaogang Hu, Whitney Hang, Yiqun Sun, Jianfeng Cai.* Development of self-immolative dendrimers for drug delivery and sensing. J. Control. Release. 2012, 159, 154-163. 1. Shruti Padhee, Yaogang Hu, Youhong Niu, Ge Bai, Haifan Wu, Frankie Costanza, Leigh West, Lacey Harrington, Lindsey N. Shaw, Chuanhai Cao, and Jianfeng Cai*. Non-Hemolytic γ- AApeptides as Antimicrobial Peptidomimetics. Chem. Commun. 2011, 47 (34), 9729-9731. References .

Dr. Jianfeng Cai (Ph.D. Advisor)

Department of Chemistry

University of South Florida

(314) 484 – 0855

acrhe8@r.postjobfree.com

Dr. Kirpal Bisht

Department of Chemistry

University of South Florida

(813) 974 – 0350

acrhe8@r.postjobfree.com

Dr. Edward Turos

Department of Chemistry

University of South Florida

813-***-****

acrhe8@r.postjobfree.com

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