Sid R. Angle, PhD

+1-301-***-**** • acps3f@r.postjobfree.com • LinkedIn Profile • Google Scholar Profile

Experienced bioengineer with a broad knowledge base in musculoskeletal & biomaterial research with

numerous publications. Well versed in product development, marketing and commercialization of

implantable orthopaedic medical devices and biomaterials.

EXPERIENCE

Senior Research Scientist – Zimmer Etex, Cambridge, MA 2013 – present

Zimmer Etex manufactures and markets proprietary calcium phosphate based biomaterials that promote bone repair and

regeneration. Zimmer Etex’s multi-segment orthopedic product portfolio brings an annual direct revenue of about $15MM.

• Principal investigator for the exploratory research & design of biomaterials and molecular carriers

• Lead scientist in project for the development and launch of 7 orthopaedic Class I/Class II devices

• Led and supervised internal and external research groups to evaluate MIS centric biomaterials

• Currently leading the development of 2 products with forecasted annual revenue of $30MM

• Co-ordinated analysis of pre-clinical, clinical and research studies including PMCF

• Product development through design control, risk analysis (FMEA), validations and verifications

• Maintained QMS (ISO 13485, ISO 14971, etc) compliance as per US FDA and CE guidelines

• Managed a $2.5 million R&D budget and annual spend plan. Co-managed the IP portfolio

• Supported drafting regulatory strategies, submissions and responses (US FDA 510K and CE)

• Supported development of all direct and private label scientific marketing presentation materials

• Train and support dedicated marketing & sales professionals for existing product lines

• Serve as subject matter expert, interfacing with HCPs, KOLs, hospital managers & executives

• 3 full length journal publications, 4 conference publications and several podium presentations

Postdoctoral Research Scientist – Carnegie Mellon University, Pittsburgh, PA 2011 – 2013

Carnegie Mellon University is focused on catalyzing sustainable industry-responsive multidisciplinary research in complex

engineered materials, devices & systems through an education environment centered around technology transfer.

• Lead investigator to spatially control tissue regeneration through biopatterning of growth factors

• Managed a cross-functional project with three conjoint studies (NIH-NIBIB R01 EB004343-06)

• Developed a technique to inhibit heterotopic ossification in a translational model of tendon injury

• Developed the biopatterning technology for regenerating a bone-tendon-muscle multi-tissue unit

• Established 3 new pre-clinical models, involving soft tissue defects for translational research

• 3 full length journal publications, 2 conference publications, 2 podium presentations and 1 patent

2008 – 2011

Doctoral Candidate – Rush University and University of Illinois, Chicago, IL

PhD Dissertation: The combined use of rhBMP-2 and low intensity pulsed ultrasound to enhance bone

healing in large segmental defects (NIH-NIAMS R21 AR057153-02).

MS Thesis: Osteogenic differentiation of rat bone marrow stromal cells by different intensities of low

intensity pulsed ultrasound (funded by Smith and Nephew).

References available upon request

• Developed a technique to enhance bone healing in a translational model of fracture non-unions

• Designed & developed a new segmental defect model - generated $500K from NIH & DOD grants

• 6 full length journal publications, 9 conference publications, 2 podium presentations and 1 patent

EDUCATION

Doctor of Philosophy 2011 Anatomy & Cell Biology Rush University Medical Center, Chicago

Bioengineering University of Illinois, Chicago

Master of Science 2007 Anatomy & Cell Biology Rush University Medical Center, Chicago

Bioengineering University of Illinois, Chicago

References available upon request

References available upon request

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