Yongmei Kathy HU

**** ****** ***. *** *** Burbank, CA 91504 626-***-**** acovgj@r.postjobfree.com

Summary of Qualif ications

Over 10 years of Hand on experience on chromatography and spectroscopy analysis, NMR,

FTIR, UV/Vis, HPLC (UV/vis, PAD, FLD, RI, ELSD), IC, AA, SFC, GC FID,

GC/MS/MS, LC/MS, LC MS/MS, CE, in pharmaceutical fields;

New drug developments, formulation design/improvments, methods developments/

validations;

Isolation, Purification and structure elucidation of API (active pharmaceutical ingredient)

from natural products using a variety of column chromatography;

DMPK (PK/PD relationships), metabolic/ proteomics on animal models and clinical

patients;

Experiences on handling small animals (dosing and harvesting plasma, urines, feces,

tissues);

Cell cultures, MTT, SRB, Flow Cytometry, Western blot, ELISA, EIA, ELFA,

PATHATRIX, RTPCR, VIDAS, TPC techniques; Establishing animal models of cancer,

hytriglycerides, fatty liver

Familiar with the analytical software of Waters Mass Lynx, Fraction Lynx, Waters Clarity,

Waters Empower II, Agilent MassHunter and ChemiStation;

Familiar with MS software programs (Word, EXCEL, PPT) and ChemDraw;

Familiar with ISO/IEC 17025, ISO 9001 2000, ISO13485 2003, AOAC, FDA, USP, USDA,

IHC documents and requirements; Familiar with USP, EP, JP, AOAC, EPA, ICH, BAM,

ASTM Methods;

Methods Development, validation, modification, Quality control and Quality insurance;

Personal training.

Professional Experience

Analytical laboratories. Burbank, CA.

Senior Chemist 2013 Present,

Chemical and biological analysis on Environments, pharmaceuticals, drug of abuse, food

nutrition panel, dietary supplements, vitamins, minerals, cosmetics, and pesticides,

organic residue solvent, toxins, etc.

Operation and maintenance of HPLCs, Ion Chromatography, SEC, AA, GC FID, GC

headspace, GC/MS, GC/MS/MS, UV, FTIR, Spectrophotometer;

Carry out new Methods Developments, validations, OOS investigations, new personal

training;

CA.

Food Safety Analytics, Turlock,

Lab Manager of Chemistry Department October 2012 March 2013,

Aflatoxins, Mycotoxins methods validations per USDA requirements;

Personal training, instrument maintenance; QA, QC

Development and review food safety analysis SOPs, testing methods and protocols.

School of Chinese Medicine, of Hong Kong Baptist University, HK

Research Associate II, March 2011 September 2012

Pharmacokinetic, Metabolimics/Proteomic research; Cancer, hyperlipidemia research by

LC/MS/MS

Medical School, The Hong Kong University. Hong Kong

Postdoctoral Research Fellowship March 2008 March 2011,

Oncology and PKDM research on clinical patients and animal models by LC/MS/MS

Formulation design and new drug developments;

Mechanism study of Chinese Medicine, Patent drugs, natural herbs and pharmaceuticals;

Biotechnology Research Institute, the HKUST, Hong Kong

Visiting Scholar, September 2006 March 2008

Neurodegenerative diseases research on cells

Isolation, purification and elucidation of regenerative active ingredients from medicinal

herbs by using UV/Vis, FT IR, HRMS, NMR and X ray spectroscopic analysis

Education & Certifications

v Ph.D. majored in Medicinal Chemistry, China Pharmaceutical University, 2003

2006

v Master of Science in Pharmacology, China Pharmaceutical University. 2000 2003

v Bachelor in Science in Chinese Pharmacology at Shandong University of Chinese

Medicine. 1996 2000 (All degrees were evaluated in Sacramento, CA, United States)

Academic Publications

I. Patent

Tang, Chunshan; Ye, Wencai; Hu, Yongmei. Sulfonated andrographolide derivatives

and pharmaceutical

compositions. Chinese Patent (2005), 26 pp. 200*-********

II. SCI Papers Published in 2008~2012

1.Yongmei Hu, Hiu Yee Kan, Journal of proteome Research, 2013, 1(29): A L.

2. Hiu Yee Kwan, Yongmei HU, Journal of Gastroenterology, 2012.

3. Yongmei Hu, Journal of pharmaceutical and Biomedical Analysis, 2011, 56 (2): 210

220

4. Yongmei Hu, Journal of Microbiology and Biotechnology. 2011, 21 (6), 582 589

5. Yongmei Hu. Global journal of Analytical Chemistry, 2011, 2 (2), 214 223

6. Yongmei Hu. Global journal of Analytical Chemistry, 2010, 1 (1), 29 43

7. Yongmei Hu, Dammarane Saponins from Gynostemma pentaphyllum. Phytochemistry,

2010, 71

(10), 1149 1157.

8. Yongmei Hu, Biomedical Chromatography 2010, 24 (4), 438 453.

9. Yongmei Hu, Identification of the major chemical constituents and their metabolites in

rat

plasma. Biomedical Chromatography 2010, 24 (5), 479 489

10. Yongmei Hu, Simultaneous analysis of lipid soluble constituents of ErxianDecoction

by using

gas chromatography and mass spectrometry. Chromatographia 2009, 70,1171 1177

11. Yongmei Hu,. Chromatographia 2009, 70, 613 618

12. Yong mei Hu, A new sesquiterpene from. Natural product Research, 2009, 23 (14)

1279 1283.

13. Yongmei Hu, New Triterpenoid from Stellaria media (L.)Cyr. Natural product

Research, 2009,

23-14-127*-****.

14. Yongmei Hu, Sesquiterpenoids from Homalomena occulta effect osteoblasts

proliferation,

differentiation and mineralization in vitro, Phytochemistry, 2008, 69, 2367 2373

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