Christina Thomas

**** ********** ******

Houston, TX 77030

Email: acgp58@r.postjobfree.com

Ph: 213-***-****

PROFFESSIONAL EXPERIENCE

Project Intern: 22 Sept 2014 - Present (Part time)

Baylor College of Medicine, Dept of Neurology, Houston, TX 77030

Responsibilities: Coordinating the recruiting of research subjects for a

study involving specialized MRI scanning tests.

Research Assistant: 01 June 2011 - 14 Feb 2013

Thrombosis Research Unit, Biomedical Technology Wing, Sree Chitra Tirunal

Institute for Medical Sciences and Technology (SCTIMST), Thiruvanathapuram,

India. Responsibilities: Worked in Indian Council of Medical Research

(ICMR) funded Project to develop an injectable and implantable drug

delivery vehicle using human proteins as agent for immobilizing curcumin

and to attain sustained release which is the basis in cancer therapy.

Achievements:

1. Published Paper:

Thomas, C., Pillai, L.S. and Krishnan, L. (2014) Evaluation of Albuminated

Curcumin as Soluble Drug Form to Control Growth of Cancer Cells in Vitro.

Journal of Cancer Therapy, 5, 723-734.

2. Patent: Indian patent - No. 2200/CHE/2013.

PCT application number: PCT/IN2014/000338 - Filed on 20th May, 2014.

3. Second author research paper under process.

Research Associate: 08 Sept 2010 - 27 May 2011,

Science and Technology Promotion Division (STPD), Kerala State Council for

Science Technology and Environment (KSCSTE), Thiruvanthapuram, India

Program involved- Science research Scheme (SRS) and Scheme for promoting

young talents in Science (SPYTiS).

Responsibilities: Involved in the scientific management with administrative

responsibility of conducting various administrative procedures for

evaluating and recommending the project proposals submitted by various

researchers to KSCSTE for financial and technical assistance pertaining to

areas of Life sciences, Agriculture, Physical and Chemical Sciences, under

the SRS and SPYTiS Scheme.

Assistant Professor: 23Nov 2006 - 31Jan 2010

Department of Biotechnology, Rajiv Gandhi College, Madhya Pradesh, India

- Handled theory classes for undergraduate and postgraduate courses in

Biotechnology and Biochemistry. (Subjects dealt: Immunology, Biochemistry,

Enzymology, and Pharmaceutical Biotechnology).

- Handled Biochemical Practical classes and organized one-day workshop,

'Microbiological World', participated by multiple colleges, at the Rajiv

Gandhi College. -- Led a one-day demonstration on Enzyme Immobilization and

ELISA by students of Rajiv Gandhi College.

ACADEMIC QUALIFICATIONS

2004 BS Chemistry - with subsidiary Mathematics and Physics, Mahatma

Gandhi University, India. GPA: 3.78.

2006 MS Biochemistry, Bharathiar University, India. GPA: 3.85.

- Dissertation Title: Kinetic Parameters of Glutamate Dehydrogenases

Activity in the Cerebellum of Adrenalectomized and Hydrocortisone treated

Mice, Center of Neurosciences, Cochin University of Science and

Technology, India. Description/Objective: Measurement of the activity of

Glutamate Dehydrogenase in Adernalectomized and Hydrocortisone treated

mice, to determine the significance of Hydrocortisone in treating

adrenalectomized mice.

AWARDS

Proficiency Certificate in Biochemistry from Karpagam Arts and Science

College, Coimbatore, India

TRAINING AND SEMINARS

- Underwent 30-day training at C.M.C Hospital, Kottayam, Kerala, India

where I got a thorough exposure to various diagnostic tests.

- Participated in National Conference on 'Technological Advancements in

Clinical Biochemistry' - organized by Karpagam Arts & Science College

(2005)

- Attended State-level Seminar on 'Recent Trends in Biochemistry'-

organized by Dr. N.G.P. Arts and Science College, Coimbatore (2005).

PROFESSIONAL AFFILIATIONS

Life Member, Society of Biotechnologists (India). Regd No.ER57\95.

SKILL SET:

. Isolating primary cells (Human Vein Endothelial Cells, HUVEC),

maintaining and handling of primary cells (Human Fibroblast Cells, Sheep

Fibroblast Cells).

. Handling and maintaining cancer cell lines (Lung, Breast, Glioma,

Prostate, Leukemia, Lymphoma cell lines for study).

. Cryopreservation.

. Apoptosis assay using flow cytometry (Aria, BD and Beckmann coulter).

. Cell cycle arrest using flow cytometry.

. Knowledge of FlowJo software,BD FACS Diva, Leica &Agilent Chem

Station.

. Chromatography

. Gel permeation chromatography - preparation and packing of the column

with Sephadex beads.

. Ion exchange chromatography.

. Paper chromatography - ascending, descending and radial

chromatography, development of chromatogram.

. Thin layer chromatography.

Others:

. Spectrophotometer.

. Protein purification using dialysis.

. Qualitative and quantitative analysis of carbohydrate, proteins and

amino acids.

. Staining techniques.

. Basic microbiology techniques.

. Maintenance of Animal Tissue Culture labs.

. DNA isolation from plants. Immunological assays - single diffusion and

double diffusion.

. Immunological assays - single diffusion and double diffusion.

. Enzyme assay and immobilization in alginate beads.

. Western blotting, Silver staining,PCR

. Handling of various equipments such as ELISA reader, PCR,refrigerated

centrifuge,bioreactor, pH meter, lyophiliser, steam sterilizer,

laminar flow, CO2 incubator, Incubator shaker, shaking water bath, hot

air oven, Bright field and inverted phase contrast microscopes, flow

cytometer, incubator.

. Familiarity with Gravimetric analysis.

AREAS OF RESEARCH INTEREST:

. Cancer Biology and Therapeutics

. Drug targeting

. Immunology

REFRENCES:

1. Dr.Zulfi Haneef, MD, FRCP (UK)

Assistant Professor in Neurology,

Peter Kellaway Section of Neurophysiology

Department of Neurology, Baylor College of Medicine,

One Baylor Plaza, MS: NB302

Houston, TX 77030

Email: acgp58@r.postjobfree.com

2. Dr. Lissy Kalyana Krishnan

Scientist G and Leader

Thrombosis Research Unit

Thrombosis Research Unit

Sree chitra Tirunal Institute for medical sciences and

technology

Poojapura

Thiruvanathapuram, Kerala, India

Email: acgp58@r.postjobfree.com

3. Dr. R Prakash Kumar

Scientist F and Head

Science and Technology Promotion Division

KSCSTE, Thiruvanthapuram, India

Email: acgp58@r.postjobfree.com

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