REZA NAZARI, PhD

Cell: 647-***-**** Email: acghbp@r.postjobfree.com

Senior Scientist and Marketing Manager, candidate for a position where my knowledge and expertise are useful

HIGHLIGHTS OF QUALIFICATIONS

Posses a PhD in cell and molecular biology and a MSc in genetics

Over 19 years of industrial and academic research and teaching experience in the fields of Molecular

Biology, Cell Biology, Virology, Microbiology, and Therapeutic Natural Agents

Strong marketing and sales skills

Highly experienced in developing projects and writing patent applications, grant applications, research

proposals, protocols, SOPs, study reports, and manuscripts

Excellent knowledge and skills of recent cell and molecular biology and genomics methodology,

biochemical techniques, data analysis, and characterization techniques

Experienced in designing and conducting pre-clinical and pilot clinical trial studies in compliance with

FDA and Health Canada’s regulations

Experienced and knowledgeable in GMP, GLP, ICH-GCP, FDA and Health Canada (PHAC)

regulations

Highly motivated team-player with excellent interpersonal, communication, presentation, organization

and analytical skills, who works well independently and can meet deadlines and adhere to budget

EMPLOYMENT HISTORY

Deputy of Commerce and Head of Marketing Department 2011-2014

Rose Pharmed Biotechnology Co. (previously Pars Roos)

Participated in strategic planning of sales and marketing departments

Directed the marketing department with a team of 19 medreps and administrators

TM TM

Successfully launched NEUROTEC and re-launched ANGIPARS (a declining drug)

Facilitated drugs registrations and distributions in other countries

Managed designing and producing information and advertisement materials, such as catalogs, brochures,

pamphlets, magazine ads, posters, stands, gifts, etc.

Planned, organized and lectured in series of seminars and drug-introduction events

Scientific Consultant 2011-Present

Rose Pharmed Biotechnology Co. (previously Pars Roos)

Participated in developing projects on new drug candidates

Completed three drug-development feasibility studies

TM TM

Wrote and published two drug monographs (for ANGIPARS and NEUROTEC )

TM TM TM

Wrote and published drug catalogs and pamphlets (for ANGIPARS, NEUROTEC, IMOD, and

TM

SEPTIMEB )

Head of Research and Development 2008-2011

Alvi Armani Genomics Inc., Toronto, Canada

Directed the R&D department and established a high-tech molecular and cell biology laboratory in

compliance with GLP, FDA and Health Canada (PHAC) regulations

Provided scientific leadership and technical training for four branches of Alvi Armani Medical Inc.

Defined and led 6 research projects and clinical trials on treatments for hair loss and skin conditions, and

improvement of hair transplant technology, resulted in filing four patent applications

Discovered and examined a botanical extract for hair loss treatment

REZA NAZARI, PhD acghbp@r.postjobfree.com

647-***-**** 2

Designed and improved cell-based and organ-based assay platforms to test therapeutic agents

Developed a method for isolating 4 types of primary cells from a single human hair follicle

Invented a cloning technique for forming a de novo hair follicle

Improved the hair transplant efficiency and retainability by more than 40%

Conducted an infomercial-oriented clinical trial for selling OrigenereTM hair- and skin-care products

Research and Teaching Assistant 1999-2008

HIV Laboratory, Dept. Medical Genetics & Microbiology, University of Toronto, Canada

Participated in designing and conducted five projects on HIV-1 gene therapy strategies using ribozymes,

ribonucleases and introns, resulted in publication of seven peer-reviewed articles

Managed lab certificates renewals, budgeting, and equipments purchasing and maintenance

Trained and supervised more than 10 technicians and research project or summer students

Designed, constructed, utilized, and examined HIV-1-based lentiviral vectors for anti-HIV gene expressions

Isolated and cultured different human lymphoid cells or cell lines, applied cell modification techniques such

as transfection and transduction

Conducted molecular and cellular assays such as Q-PCR, QRT-PCR, Southern, Northern and Western

blotting, in vitro transcription, cleavage reaction, FACS, immunoflowcytometry, IP, ELISA, etc.

Karyotype Screener 1998-1999

Dr. Karimi-Nejad Pathology and Cytogenetics Centre, Tehran, Iran

Research and Teaching Assistant 1995-1997

Plant Pathology and Entomology Research Laboratories, Azad University, Tehran, Iran

VOLUNTEER EXPERIENCE

Marketing Director 2011

B & S Magazine (A Health and Wellness Free Monthly Magazine), Toronto

Directed the marketing department

Contacted health professionals and invited them to contribute in writing articles

Recruited activists and participated in organizing wellness activities

Member of Board of Directors, Coordinator of Material Translation Team 2005-2011

Iranian Cancer Support Group (ICSG), Toronto

Participated in establishing the group, writing the constitution and making the group’s policies

Directed a team for writing, translation, and preparation more than 70 articles and brochures for distribution

to physicians’ offices and main hospitals in GTA

Liaised between ICSG and the Canadian Cancer Society’s National Office to facilitate community outreach

Member of Community Advisory Committee 2007

The Immigrant Women’s Health Centre (IWHC), Toronto

Collaborated in preparing a fact sheet for increasing awareness and knowledge of the Ontario’s Persian

community about HIV/AIDS

Co-founder and Member of Board of Directors 2005-2007

Persian-Canadian Biomedical Scientists (PCBMS), Toronto

Participated in establishing the group, writing the constitution and making the group’s policies

Organized events and recruited speakers for scientific forums

Member of Organizing Committee 2004-2007

Life Science Career Development Seminar series (LSCDS), Toronto

Participated in making the group’s policies and recruiting speakers for by-weekly seminars, networking

workshops and three “Career Development Conferences” at University of Toronto

REZA NAZARI, PhD acghbp@r.postjobfree.com

647-***-**** 3

EDUCATION

Ph.D. in Cell and Molecular Biology 2008

Dept. of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

Thesis title: RNA and DNA Inactivation Strategies to Prevent/Inhibit HIV-1 Replication.

M.Sc. in Genetics 1998

Joint program of Pasteur Institute of Iran and Azad University, Tehran, Iran.

Thesis title: A Study of Recombination in Streptomyces griseoflavus by Intra-Specific Protoplast Fusion and

Its Effect on the Production of Desferrioxamine.

B.Sc. (Hons) in Biology 1995

Azad University, North Tehran Campus, Tehran, Iran

PROFESSIONAL DEVELOPMENT AND TRAININGS

Molecular Docking (Laboratory of System Biology and Bioinformatics, University of Tehran) 2014

Level 2 and 3 (HIV and hepatitis) Laboratory Biosafety, OSHA, WHMIS (University of Toronto) 2007

Radioisotope Safety (University of Toronto) 2005

Handling Laboratory Animals (University of Toronto) 2004

Teaching Assistance Training (University of Toronto) 2003

Advanced Molecular Biology of Viruses (National Center of Biotech. & Genetics Eng. Res., Iran) 1995

TECHNICAL SKILLS

Molecular biology: Highly skilled in molecular assays and techniques such as Q-PCR, QRT-PCR, Real-time

PCR, primer designing, Southern, Northern and Western blotting, ELISA, IP and immunofluorescence

assays, in vitro transcription, TLC, GC and HPLC

Cell biology: Highly experienced in isolating and culturing human stem cells, primary cells and cell lines,

and using them in cell-based assays such as transfection, transduction, flowcytometry, FACS, cytotoxicity,

cell viability, cell proliferation, apoptosis, DNA damage, chromosome staining, karyotyping, G-banding

Computer: Proficient in Microsoft Windows 7 and lower versions; Microsoft Office 2013 and lower

versions (Word, PowerPoint, Excel, Outlook, Access, etc.); On-line programs (NCBI, Gene Bank, DNA

Blast, PrimerDesign, etc.); Devise-specific softwares (Robotic Microplate Handlers, Plate Readers,

Microscopic Imaging, Tricho-scanning)

AWARDS

Ontario Volunteer Service Award for more than 5 years of voluntarily community activities 2011

University of Toronto Life Science Award 2007

University of Toronto, Laboratory Medicine and Pathobiology Fellowship Award 2006

University of Toronto, Laboratory Medicine and Pathobiology Fellowship Award 2005

University of Toronto OSOTF Graduate Award in Laboratory Medicine and Pathobiology 2004

The Ontario HIV Treatment Network (OHTN) Studentship Award 2002-2004

University of Toronto, Laboratory Medicine and Pathobiology Fellowship Award 2002

REZA NAZARI, PhD acghbp@r.postjobfree.com

647-***-**** 4

PATENTS

1. Extracts and compounds from a plant extract for increasing hair growth, Alvi Armani Inc 2013

2. Composition and methods for hair follicle generation, Alvi Armani Genomics Inc. (pending) 2011

3. Personalized composition for increasing hair growth, Alvi Armani Genomics Inc. (pending) 2011

4. Extracts and compounds from a plant extract for removing unwanted hair, AAG Inc. (pending) 2011

PUBLICATIONS

MAPT Gene Polymorphisms in Iranians Suffering from Sporadic Alzheimer’s Disease (in preparation)

1.

Effects of IMODTM and ANGIPARSTM on Progresses of Sporadic Alzheimer’s Disease (in preparation)

2.

3. Khorram Khorshid HR, Arastoo M & Nazari R. Extraction methods, related chemical components, HPLC

analysis, biological evaluation, and the therapeutical role of Melilotus officinalis (L.) (Submitted)

4. Farzamfar B, Nazari R & Bayanolhagh S. “Diabetic Foot Ulcer” in Gangrene Management-New

Advancements and Current Trends, Editor A. Vitin (2013)

5. Nazari R & Joshi S. “HIV-1 Gene Therapy at Pre-Integration and Provirus DNA Levels”. Curr. Gene

Ther. (2009), 9(1):20-5. Review

6. Nazari R & Joshi S. “Exploring the Potential of Group II Introns to Inactivate HIV-1”. J. Gen. Virol.

(2008), 89(Pt 10):2605-10

7. Nazari R, Ma XZ & Joshi S. “Inhibition of HIV-1 Entry Using Vectors Expressing a Multimeric

Hammerhead Ribozyme Targeted Against the CCR5 mRNA”. J. Gen. Virol. (2008), 89(Pt9):2252-61

8. Nazari R & Joshi S. “CCR5 Co-receptor as a Target for Inhibiting HIV-1 Entry”. Curr. Gene Ther.

(2008), 8(4):264-72.

9. Ramezani A, Ma XZ, Nazari R & Joshi S. “Development and Testing of Multimeric Hammerhead

Ribozymes Targeted Against HIV-1 RNA from All Major Subtypes”. Front. Biosci. (2002), 7: 29-36.

10. Ding SF, Lombardi RA, Nazari R & Joshi S. “A Combination Anti-HIV-1 Gene Therapy Approach Using a

Single Transcription Unit that Expresses Antisense, Decoy, and Sense RNAs, and Trans-Dominant Mutant

Gag and Env proteins”. Front. Biosci. (2002), 7: 15-28.

11. Arora A, Nazari R, Lamothe B, Singwi S, Joshi S. “Design and Construction of Oncoretroviral Vectors

Expressing a Packageable Ribonuclease for Use in HIV Gene Therapy”. Gene Ther. Mol. Biol. (2001), 6:

57-67.

PRESENTATIONS

The complete list of 45 international and national presentations will be provided upon request.

REFERENCES

Available upon request.

Contact this candidate